4.4 Review

Experimental and modeling approaches in characterizing coating uniformity in a pan coater: A literature review

Journal

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
Volume 17, Issue 2, Pages 134-147

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/10837450.2011.649852

Keywords

Coating; coefficient of variation; particle tracking techniques; modeling approaches; tablets

Funding

  1. NSF-Center for Pharmaceutical Processing Research (CPPR)
  2. University of Connecticut Research Foundation (UCRF)

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This review provides a comprehensive record of experimental and modeling approaches that can be used to study the effect of critical process parameters affecting the coating uniformity in pharmaceutical coating operation. Explicit reference is given to the development of the approach and its previous usage with particular emphasis on the advantages, limitations and model assumptions.

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