Article
Food Science & Technology
Aysen Melda Colak, Kerem Mertoglu, Fatma Alan, Tuba Esatbeyoglu, Ibrahim Bulduk, Erten Akbel, Ibrahim Kahramanoglu
Summary: It is important to provide species with high nutritional value as fresh or processed products for human consumption in order to achieve balanced nutrition. In this study, 15 naturally grown European Cranberry bush (ECB) genotypes were characterized in terms of horticultural characteristics, and it was found that they have significant levels of organic acids, total phenolic content, and total flavonoid content. Pomological characteristics were positively correlated with each other, but negatively correlated with chemical properties. Low pH was identified as an important factor for obtaining higher amounts of phytochemicals and strong antioxidant effects.
Article
Biochemistry & Molecular Biology
Sylwia Golawska, Iwona Lukasik, Adrian Arkadiusz Chojnacki, Grzegorz Chrzanowski
Summary: Guelder rose (Viburnum opulus L.) is a plant known for its health benefits due to the presence of phenolic compounds. This study aimed to compare the phenolic acids and flavonoids content in the leaves of cultivated and wild V. opulus, and investigate the effects of temperature and place of occurrence on their content and composition.
Article
Chemistry, Multidisciplinary
Monika Mazur, Anna Marietta Salejda, Kinga Maria Pilarska, Grazyna Krasnowska, Agnieszka Nawirska-Olszanska, Joanna Kolniak-Ostek, Przemyslaw Babelewski
Summary: The addition of freeze-dried guelder rose fruit powder can reduce the microbial count in meat products, but high amounts may increase cooking loss and impact taste and smell. Future research will focus on freeze-dried encapsulation and other solutions to address these issues.
APPLIED SCIENCES-BASEL
(2021)
Article
Agricultural Engineering
Tugba Dursun Capar, Tugba Dedebas, Hasan Yalcin, Lutfiye Ekici
Summary: This study investigated the impact of different extraction techniques on European cranberrybush seed oil, finding that ultrasound-assisted extraction and microwave-assisted extraction could effectively increase oil yield without deteriorating oil quality. The extraction method did not significantly alter the fatty acid composition and oil quality.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Chemistry, Applied
Lijana Dienaite, Renata Baranauskiene, Petras Rimantas Venskutonis
Summary: In this study, lipophilic extracts from Viburnum opulus and Hippophae rhamnoides berries were recovered using supercritical CO2 extraction method, and their composition was analyzed. It was found that the diversity of triacylglycerols was higher in Hippophae rhamnoides, while the fatty acid composition was more balanced in Viburnum opulus. All extracts showed improved oxidative stability of mayonnaise.
Article
Food Science & Technology
Gizem Ozan, Alev Cumbul, Engin Sumer, Ahmet Aydin, F. Yesim Ekinci
Summary: The acute and subacute oral toxicities of European cranberrybush (ECB) fruit juice were evaluated in rats and mice. The study found that high doses of ECB juice were toxic to the kidney, liver, and adipose tissue in mice. It emphasizes the importance of considering the dosage of dietary supplements containing high levels of phenolic compounds.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Review
Food Science & Technology
Maria C. Tenuta, Brigitte Deguin, Monica R. Loizzo, Claire Cuyamendous, Marco Bonesi, Vincenzo Sicari, Lorenza Trabalzini, Anne-Claire Mitaine-Offer, Jianbo Xiao, Rosa Tundis
Summary: Cornus species, including Cornus mas and Cornus officinalis, are widely distributed in Europe, Africa, Asia, and America, and their edible fruits are known for their nutritional and medicinal values. These fruits contain various secondary metabolites with nutritional and functional properties. Although there is limited information available on the phytochemicals and biological activities of Cornus species, their potential for applications in the food industry and traditional medicine is of growing interest.
Article
Plant Sciences
Vasileia Chioti, Konstantina Zeliou, Aikaterini Bakogianni, Charikleia Papaioannou, Antonis Biskinis, Constantinos Petropoulos, Fotini N. Lamari, Vasileios Papasotiropoulos
Summary: Eggplant is a vegetable with high nutritional value and antioxidant content. The levels of carbohydrates, proteins, phenolics, anthocyanins, flavonoids, chlorogenic acid, and antioxidant capacity vary among different cultivars. The cultivars 'EMI' and 'Lagkada' have higher levels of phenolics, anthocyanins, ascorbic acid, caffeoylquinic acid, and antioxidant capacity. Sequence analysis reveals polymorphisms in key regulating genes of the phenylpropanoid pathway. These polymorphisms can potentially be used as molecular markers in eggplant breeding.
Article
Forestry
Guijun Han, Guoqing Bai, Yongpeng Wu, Yafu Zhou, Wenjing Yao, Long Li
Summary: This study compared the levels of CGA and flavonoids accumulation in the rhizomes of I. germanica and I. pallida at the transcriptome and metabolome levels. The results revealed the differences in the biosynthesis and regulation of CGA and flavonoids between the two species. Key genes and transcription factors related to this process were identified.
Article
Nutrition & Dietetics
Patrick Solverson, George P. Albaugh, Hawi A. Debelo, Mario G. Ferruzzi, David J. Baer, Janet A. Novotny
Summary: Berries and other foods rich in anthocyanins show anti-obesity effects but their bioactive components and mechanisms are not well understood. An intervention study was conducted on overweight and obese adults to study the effects of different berry components on cellular respiration. Results showed that high-anthocyanin, low-fiber treatment (berry juice) and low-anthocyanin, high-fiber treatment (fiber-enriched gelatin) had opposite effects on cellular respiration.
Article
Biochemistry & Molecular Biology
Cecilia Georgescu, Adina Frum, Lidia-Ioana Virchea, Anastasiia Sumacheva, Mark Shamtsyan, Felicia-Gabriela Gligor, Neli Kinga Olah, Endre Mathe, Monica Mironescu
Summary: The aim of this study was to investigate the chemical composition, antioxidant and antimicrobial activities of eight types of berries from Romania and Russia. The results showed that berries from Romania were richer in antioxidant compounds compared to berries from Russia. The antioxidant activity and chemical composition of the berries were influenced by cultivation conditions.
Article
Agriculture, Multidisciplinary
Andre Seco, Nuno Basilio, Natercia F. Bras, Kumi Yoshida, Tadao Kondo, Kin-ichi Oyama, Fernando Pina
Summary: This study investigated the copigmentation constant between delphinidin 3-O-glucoside and chlorogenic acid using UV-vis measurements and stopped flow technique. The results showed that the interactions of flavylium cation and quinoidal base with the neutral or the negatively charged forms of the copigment have different geometries. Computational calculations also predicted identical relative order for the binding energies of the four adducts.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Chemistry, Applied
Onur Sevindik, Gamze Guclu, Bilal Agirman, Serkan Selli, Pinar Kadiroglu, Matteo Bordiga, Esra Capanoglu, Hasim Kelebek
Summary: This study compared synthetic juice and fermented juices with three commercial lactic acid bacteria. It found that fermented juice samples had higher levels of phenolics and volatiles, but lower amino acid contents. Juices produced with L. plantarum and L. delbrueckii showed better sensory properties.
Article
Biology
Berna Erdal, Seydi Yikmis, Nazan Tokatli Demirok, Esra Bozgeyik, Okan Levent
Summary: This study evaluated the characteristics and activities of gilaburu vinegar prepared using different methods. Ultrasound treatment showed better enrichment of phenolic compounds and amino acids compared to thermal pasteurization. Gilaburu vinegar was found to be rich in important minerals, and ultrasound treatment increased the iron content. Gilaburu vinegar exhibited antimicrobial and anticancer activities. Therefore, ultrasound treatment is of great significance in terms of the bioactivity and nutritional value of gilaburu vinegar.
Review
Biochemistry & Molecular Biology
Bogdan-Stefan Negreanu-Pirjol, Ovidiu Cristian Oprea, Ticuta Negreanu-Pirjol, Florentina Nicoleta Roncea, Ana-Maria Prelipcean, Oana Craciunescu, Andreea Iosageanu, Victoria Artem, Aurora Ranca, Ludmila Motelica, Anca-Cristina Lepadatu, Madalina Cosma, Dan Razvan Popoviciu
Summary: Lonicera caerulaea L. and Aronia melanocarpa (Michx.) Elliot fruits are rich in bioactive compounds and have numerous health benefits. L. caerulea has higher antioxidant activity and ascorbic acid level compared to commonly consumed berries like blackberries and strawberries. A. melanocarpa is known for its high antioxidants content, surpassing other fruits like currants, cranberries, blueberries, elderberries, and gooseberries. This review aims to highlight the potential health benefits of these fruits and promote their cultivation and processing as nutraceutical sources.
Article
Biochemical Research Methods
Alexey V. Kozlov, Galina V. Ramenskaya, Dmitry A. Sychev, Alexander M. Vlasov, Lyubov M. Makarenkova, Elena S. Stepanova, Vladimir I. Gegechkori, Snezana Agatonovic-Kustrin, Victor V. I. Chistyakov
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2019)
Article
Chemistry, Medicinal
M. D. Khorol'skii, O. V. Anan'ina, A. A. Chaplenko, I. V. Nedkov, N. V. Maslennikova, G. V. Ramenskaya
PHARMACEUTICAL CHEMISTRY JOURNAL
(2019)
Article
Chemistry, Medicinal
N. E. Uvarova, N. N. Eremenko, G. V. Ramenskaya, D. V. Goryachev, V. V. Smirnov
PHARMACEUTICAL CHEMISTRY JOURNAL
(2019)
Article
Chemistry, Medicinal
N. E. Uvarova, N. N. Eremenko, G. V. Ramenskaya, D. V. Goryachev
PHARMACEUTICAL CHEMISTRY JOURNAL
(2020)
Article
Chemistry, Medicinal
P. A. Kakorin, T. Fateeva, O. Tereshkina, I. B. Perova, G. Ramenskaya, S. S. Sologova, K. Eller
PHARMACEUTICAL CHEMISTRY JOURNAL
(2020)
Article
Chemistry, Analytical
Snezana Agatonovic-Kustrin, Galina Ramenskaya, Ella Kustrin, Davoud Babazadeh Ortakand, David W. Morton
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2020)
Article
Biochemical Research Methods
Snezana Agatonovic-Kustrin, Galina Ramenskaya, Ella Kustrin, David W. Morton
Summary: A high-performance thin-layer chromatography method coupled with microchemical derivatization and bioassay was used for bioanalytical profiling of selected marigold plant extracts. Different extracts showed variations in antioxidant activity and alpha-amylase inhibition, and the main components responsible for these activities were identified through detailed analysis.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Chemistry, Medicinal
N. E. Uvarova, N. N. Eremenko, G. V. Ramenskaya, D. V. Goryachev
Summary: A bioequivalence (BE) study is crucial for the registration of oral generic drugs, with the planning influenced by factors such as the linearity of pharmacokinetics. Regulatory requirements for drugs with non-linear pharmacokinetics, like atazanavir and valaciclovir, must be considered in planning BE studies. Differences in tested drug dosages and number of tests performed were found in analysis of protocols and reports of BE studies, highlighting the importance of taking into account all characteristics of the active substance for BE studies of drugs with non-linear pharmacokinetics.
PHARMACEUTICAL CHEMISTRY JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Makar A. Gerasimov, Irina B. Perova, Konstantin I. Eller, Michail Y. Akimov, Anna M. Sukhanova, Galina M. Rodionova, Galina V. Ramenskaya
Summary: The purpose of this study was to investigate the qualitative and quantitative composition of biologically active substances in the fresh fruits of five different varieties of black chokeberry. Samples were obtained from the Michurin Federal Scientific Center in the Tambov region of Russia. Using modern chemical-analytical methods, the content and profiles of various compounds were determined, including anthocyanin pigments, proanthocyanidins, flavonoids, hydroxycinnamic acids, organic acids, monosaccharides, disaccharides, and sorbitol. The most promising varieties in terms of bioactive substance content were identified based on the results.
Meeting Abstract
Toxicology
A. K. Taldaev, E. V. Melnik, M. V. Belova, S. V. Kozin, G. V. Ramenskaya
TOXICOLOGY LETTERS
(2021)
Meeting Abstract
Toxicology
Elizaveta V. Melnik, Maria V. Belova, Igor A. Tyurin, Mikhail M. Potskhveriya, Anastasia Yu Simonova, Yuri N. Ostapenko, Galina N. Sukhodolova, Galina V. Ramenskaya
CLINICAL TOXICOLOGY
(2021)
Meeting Abstract
Allergy
V Kovchina, I Shilovskiy, V Smirnov, G. Ramenskaya, E. Egorenkov, V Turenko, O. Koloskova, Y. Sebyakin, D. Kudlay, M. Khaitov
Article
Medicine, Research & Experimental
V. G. Kukes, O. K. Parfenova, B. K. Romanov, A. B. Prokofiev, E. Parfenova, N. G. Sidorov, A. A. Gazdanova, L. Pavlova, V. Zozina, A. D. Andreev, T. Aleksandrova, S. Chernova, G. Ramenskaya
SOVREMENNYE TEHNOLOGII V MEDICINE
(2020)
Review
Biochemistry & Molecular Biology
Valeriy V. Smirnov, Evgenii A. Egorenkov, Tatiana N. Myasnikova, Alexey E. Petukhov, Vladimir I. Gegechkori, Anna M. Sukhanova, Galina V. Ramenskaya
Review
Pharmacology & Pharmacy
Elizaveta Fisher, Kirill Pavlenko, Alexander Vlasov, Galina Ramenskaya
PHARMACEUTICAL MEDICINE
(2019)
