Article
Agricultural Economics & Policy
Ceren Mutlu
Summary: The purpose of this study was to produce an enriched honey powder with active compounds from bee pollen and investigate the effects of bee pollen addition as a carrier material on honey powder. The results showed that increasing the concentration of bee pollen in the mixture led to larger particle size, higher phenolic, flavonoid and sugar contents, and increased antioxidant activity of the enriched honey powder. However, it also reduced the flow properties and solubility of the honey powder samples.
BRITISH FOOD JOURNAL
(2023)
Article
Food Science & Technology
Pasquale Filannino, Raffaella Di Cagno, Giuseppe Gambacorta, Ali Zein Alabiden Tlais, Vincenzo Cantatore, Marco Gobbetti
Summary: The study utilized an integrated metabolomic approach to investigate the impact of starter cultures on the volatilome and bioaccessible phenolics profile of fermented bee-collected pollen. Fermentation increased volatile compounds and altered their proportions, with the profile depending on the type of fermentation. Started-BCP had higher levels of esters and alcohols, while both types of fermented BCP showed increased bioaccessible phenolics compared to unprocessed raw BCP.
Article
Biochemistry & Molecular Biology
Angelica Faith L. Suarez, April Dawn G. Tirador, Zenith M. Villorente, Cathrina F. Bagarinao, Jan Vincent N. Sollesta, Gerard G. Dumancas, Zhe Sun, Zhao Qi Zhan, Jonel P. Saludes, Doralyn S. Dalisay
Summary: This study investigated the antibacterial and antioxidant activities of honey from Apis mellifera and Tetragonula biroi in the Philippines, revealing that honey produced by T. biroi has higher flavonoid and phenolic content compared to A. mellifera, and identified the compound responsible for its antibacterial activity. These findings suggest that Philippine honey, particularly from T. biroi, may have potential antibiotic and antioxidant properties.
Article
Biochemistry & Molecular Biology
Celina Habryka, Robert Socha, Leslaw Juszczak
Summary: The study confirmed that enriching honey with bee pollen significantly increased the content of phenolic compounds, improving its antioxidant and antiradical activities, but resulting in a deterioration of its sensory properties.
Article
Biochemistry & Molecular Biology
Aleksandar Z. Kostic, Danijel D. Milincic, Nebojsa Nedic, Uros M. Gasic, Bojana Spirovic Trifunovic, Denis Vojt, Zivoslav Lj. Tesic, Mirjana B. Pesic
Summary: This study investigated the phenolic and fatty acid profile, antioxidant properties, and nutritional characteristics of monofloral bee-collected artichoke pollen for the first time. Results showed that the pollen contained a high concentration of flavonol glycosides and ferulic acid, along with predominantly unsaturated fatty acids. The pollen exhibited strong antioxidant activity and a balanced ratio of omega-6 to omega-3 fatty acids, making it a promising source of antioxidants with potential health benefits. Additional antioxidant studies are recommended to further validate these findings.
Article
Chemistry, Multidisciplinary
Celina Habryka, Robert Socha, Leslaw Juszczak
Summary: The aim of this study was to investigate the influence of bee bread addition on the phenolic content, antioxidant properties, sensory and quality characteristics of the multifloral honey. The results showed that the addition of bee bread significantly increased the phenolic content and antioxidant capacity of the honey. However, it also led to unfavorable changes in the sensory characteristics, such as decreased clarity, color uniformity, and sweetness. Additionally, the addition of bee bread increased water-insoluble substances, free acidity, and proline level, while decreasing glucose and fructose content.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Tomasz Sawicki, Malgorzata Starowicz, Lucyna Klebukowska, Pawel Hanus
Summary: This study aimed to characterize the chemical composition, antioxidant potential, and antimicrobial activity of bee products. The results showed that bee pollen and bee bread had stronger antioxidant potential, while honey was more effective against Gram-positive bacteria.
Article
Biochemistry & Molecular Biology
Vaida Adaskeviciute, Vilma Kaskoniene, Karolina Barcauskaite, Paulius Kaskonas, Audrius Maruska
Summary: Solid-state lactic acid fermentation can enhance the release of bioactive compounds and increase the antioxidant activity of bee-collected pollen. The composition and levels of compounds in the pollen are influenced by geographical regions and fermentation methods.
Article
Multidisciplinary Sciences
Zahra Shakoori, Ahmadreza Mehrabian, Dariush Minai, Farid Salmanpour, Farzaneh Khajoei Nasab
Summary: Melissopalynological and chemical analysis of honey provide valuable information about its botanical and geographical origin. In this study, honey samples from two main Iranian hubs were evaluated, and all samples were classified as polyfloral honey with the standard amount of pollen. Various chemical analyses were conducted, and the presence of 42 plant families and 55 genera was identified, with Asteraceae, Fabaceae, Rosaceae, Apocynaceae, and Apiaceae being the most common. Evaluation of antioxidant activity, total phenolic content, pH, and moisture content of honey samples was also carried out.
Article
Food Science & Technology
Rabia Yildiz, Medeni Maskan
Summary: The study aimed to develop a product made with green tea, honey, and pollen, and optimized the conditions by selecting the best honey to pollen ratio and total concentration of non-tea substances. The final product exhibited high total phenolics content and total antioxidant capacity.
INTERNATIONAL JOURNAL OF GASTRONOMY AND FOOD SCIENCE
(2022)
Article
Ecology
Brendan A. Daisley, Andrew P. Pitek, Christina Torres, Robin Lowery, Bethany A. Adair, Kait F. Al, Bernardo Nino, Jeremy P. Burton, Emma Allen-Vercoe, Graham J. Thompson, Gregor Reid, Elina Nino
Summary: Optimizing delivery methods can effectively apply beneficial lactobacilli consortium (LX3) to protect honey bees and promote hive health, resulting in increased brood production and colony growth.
Article
Biochemistry & Molecular Biology
Muzamil Shah, Hasnain Jan, Samantha Drouet, Duangjai Tungmunnithum, Jafir Hussain Shirazi, Christophe Hano, Bilal Haider Abbasi
Summary: The study investigated the effects of chitosan on the production of bioactive flavonolignans in Silybum marianum suspension cultures. The results demonstrated that chitosan treatment significantly increased biomass production and the accumulation of active compounds such as flavonolignans.
Article
Biochemistry & Molecular Biology
Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo
Summary: This study comprehensively investigated the physicochemical parameters, chemical composition, and antioxidant capacity of Castanopsis honey (CH), as well as evaluated its anti-inflammatory effects. The results showed that CH has high quality and contains various compounds and phenols, which exhibit significant antioxidant and anti-inflammatory activities.
Article
Entomology
Emily R. Noordyke, Edzard van Santen, James D. Ellis
Summary: The study found that a portion of adult bees consume pollen substitute patties, but do not directly feed them to larvae or store them like bee bread. Pollen substitute patties serve as a supplement, not a replacement, for natural pollen in terms of larval provisioning and long-term storage.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2021)
Article
Multidisciplinary Sciences
Marguerite Matherne, Caroline Dowell-Esquivel, Oliver Howington, Olivia Lenaghan, Gabi Steinbach, Peter J. Yunker, David L. Hu
Summary: Honey bees transport pollen pellets by mixing them with nectar and forming them into a solid, removable form. Slow removal speeds reduce the force and work needed to remove the pellet, which is a viscoelastic material with long relaxation times that enables it to remain solid during transport and removal. This study may inspire further research into viscoelastic materials in nature.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2021)
Article
Chemistry, Applied
Hasan Kirmizibekmez, Yigit Inan, Rengin Reis, Hande Sipahi, Ahmet C. Goren, Erdem Yesilada
NATURAL PRODUCT RESEARCH
(2019)
Article
Plant Sciences
E. Celep, M. Seven, S. Akyuz, Y. Inan, E. Yesilada
SOUTH AFRICAN JOURNAL OF BOTANY
(2019)
Article
Plant Sciences
Engin Sumer, Gozde Erkanli Senturk, Ozlem Unay Demirel, Erdem Yesilada
JOURNAL OF ETHNOPHARMACOLOGY
(2020)
Article
Plant Sciences
Inci Kurt-Celep, Engin Celep, Selin Akyuz, Yigit Inan, Timur Hakan Barak, Galip Akaydin, Dilek Telci, Erdem Yesilada
JOURNAL OF ETHNOPHARMACOLOGY
(2020)
Article
Plant Sciences
Baris Gokalsin, Didem Berber, Gulsah Cobanoglu Ozyigitoglu, Erdem Yesilada, Nuzhet Cenk Sesal
Article
Food Science & Technology
Gunce Alimoglu, Etil Guzelmeric, Parla Isil Yuksel, Cansel Celik, Inci Deniz, Erdem Yesilada
Summary: This study investigated the relationship between the botanical origins, chemical compositions, and biological activities of bee pollen samples. Through palynological and chromatographic analysis, key components in bee pollen were identified, and antioxidant and antimicrobial activities were tested.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemical Research Methods
Esra Sacici, Erdem Yesilada
Summary: This study aimed to develop and validate new HPTLC methods to analyze active components in different Hypericum species. Results showed that hyperforin concentration was highest in H. triquetrifolium, H. scabrum and two H. perforatum samples; hypericin was detected in H. bithynicum, H. perfoliatum, H. triquetrifolium and two H. perforatum samples; and hyperoside was found in all tested specimens. The new HPTLC methods developed in this study may ensure reliable results for the qualification and quantification of hyperforin, hypericin and hyperoside contents in Hypericum species.
PHYTOCHEMICAL ANALYSIS
(2022)
Article
Medicine, General & Internal
Husamettin Ekici, Ali Kumandas, Abdullah Canberk Ozbaykus, Hazal Dizdaroglu, Ahmet Midi, Mehmet Sabri Balik, Erdem Yesilada
Summary: This study evaluates the efficacy of the Algan Hemostatic Agent (AHA) in three different physical forms in a rat femoral artery incision model. The results show that all forms of AHA are able to significantly reduce bleeding time, with the powder form being the most effective.
Article
Pharmacology & Pharmacy
Juste Baranauskaite, Mehmet Ali Ockun, Burcu Uner, Burcin Gungor, Gulengul Duman, Cetin Tas, Erdem Yesilada
Summary: The objective of this research was to produce fast dissolving oral films containing freeze-dried ginseng root extract and evaluate the effect of pullulan on the films. The results showed that the films with ginseng extract had desirable physicomechanical properties and fast drug release. The extract also exhibited antioxidant and anticancer effects, providing a foundation for future studies and development.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Review
Integrative & Complementary Medicine
Erdem Yesilada
Summary: Plants are important sources of drug development, but searching for phytochemicals with specific pharmacological activity is expensive and tedious. Traditional information has been recognized as significant, leading to increased interest in field surveys for traditional medicines. A survey on plants used in Turkish folk medicine found that most of them have potential antiviral activity.
CURRENT TRADITIONAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Nisa Beril Sen, Etil Guzelmeric, Irena Vovk, Vesna Glavnik, Hasan Kirmizibekmez, Erdem Yesilada
Summary: This study compared the chemical profiles, phenolic marker compounds, and pharmacological activities of ivy bee pollen samples from Turkey and Slovenia, as well as ivy flower pollen grains. The pollen samples from different locations had similar chemical profiles due to the same botanical origins. Marker compounds common to both bee pollen and flower pollen were isolated and their structures were elucidated. In vitro tests were conducted to evaluate the xanthine oxidase inhibition and antioxidant activity of the marker compounds and extracts.
Meeting Abstract
Plant Sciences
M. Erdogan, B. Aru, S. T. Yilmaz, E. Yesilada, Yanikkaya G. Demirel, H. Kirmizibekmez
Article
Pharmacology & Pharmacy
T. Yildirim, E. Yesilada, F. Eren, H. Apaydin, G. Gulbay
Summary: The study identified abnormal miRNA expressions in the plasma of patients with radiographic axial spondyloarthropathy, indicating a potential for these miRNAs to serve as diagnostic biomarkers for disease activity in ankylosing spondylitis.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2021)
Article
Chemistry, Medicinal
Ayse Esra Karadag, Aysegul caskurlu, Mehmet Evren Okur, Etil Guzelmeric, Neslihan Ustundag Okur, Fatma Tosun, Erdem Yesilada, Fatih Demirci
Summary: Preparations from the aerial parts of Cistus creticus L., traditionally used as a hemostatic agent in Anatolia, were extracted and formulated into gels. The 2.5% extract gel was found to be more effective in reducing bleeding time and amount. Major constituents responsible for the hemostatic properties were identified as hyperoside and tiliroside.
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
(2020)
Article
Pharmacology & Pharmacy
Etil Guzelmeric, Dicle Cevik, Erdem Yesilada
JOURNAL OF RESEARCH IN PHARMACY
(2020)