Activation of TRPM7 channels by small molecules under physiological conditions

Classics in Chemical Neuroscience: Clozapine

(2013) Cody J. Wenthur et al.   ACS Chemical Neuroscience

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway

(2013) Xiaojing Meng et al.   CANCER LETTERS

Timing of Myocardial Trpm7 Deletion During Cardiogenesis Variably Disrupts Adult Ventricular Function, Conduction, and Repolarization

(2013) Rajan Sah et al.   CIRCULATION

Dopamine D3 receptor as a new pharmacological target for the treatment of depression

(2013) Gian Marco Leggio et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity

(2013) R. Sah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural and synthetic modulators of SK (Kca2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7

(2012) V Chubanov et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPM7 Is Required for Breast Tumor Cell Metastasis

(2012) Jeroen Middelbeek et al.   CANCER RESEARCH

Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C γ2 (PLCγ2) using TRPM7-kinase

(2012) Francina Deason-Towne et al.   CELLULAR SIGNALLING

Upregulation of TRPM7 Channels by Angiotensin II Triggers Phenotypic Switching of Vascular Smooth Muscle Cells of Ascending Aorta

(2012) Zheng Zhang et al.   CIRCULATION RESEARCH

Cleavage of TRPM7 Releases the Kinase Domain from the Ion Channel and Regulates Its Participation in Fas-Induced Apoptosis

(2012) Bimal N. Desai et al.   DEVELOPMENTAL CELL

TRPM7: A unique channel involved in magnesium homeostasis

(2012) Tamara M. Paravicini et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration

(2012) Pierre Rybarczyk et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of podosome formation, microglial migration and invasion by Ca2+-signaling molecules expressed in podosomes

(2012) Tamjeed A Siddiqui et al.   Journal of Neuroinflammation

KCa3.1 and TRPM7 Channels at the Uropod Regulate Migration of Activated Human T Cells

(2012) Zerrin Kuras et al.   PLoS One

TRPM7 regulates polarized cell movements

(2011) Li-Ting Su et al.   BIOCHEMICAL JOURNAL

Phosphorylation of Annexin A1 by TRPM7 Kinase: A Switch Regulating the Induction of an α-Helix

(2011) Maxim V. Dorovkov et al.   BIOCHEMISTRY

Role of Melastatin Transient Receptor Potential 7 Channels in the Osteoblastic Differentiation of Murine MC3T3 Cells

(2011) Elie Abed et al.   CALCIFIED TISSUE INTERNATIONAL

EGF enhances the migration of cancer cells by up-regulation of TRPM7

(2011) Haixia Gao et al.   CELL CALCIUM

Waixenicin A Inhibits Cell Proliferation through Magnesium-dependent Block of Transient Receptor Potential Melastatin 7 (TRPM7) Channels

(2011) Susanna Zierler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy of Antidepressants as Analgesics: A Review

(2011) Pinky Dharmshaktu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The channel kinase, TRPM7, is required for early embryonic development

(2011) J. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca2+ influx

(2010) Jian-Peng Chen et al.   CELL CALCIUM

The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k

(2010) Anne-Laure Perraud et al.   CELLULAR SIGNALLING

TRPM7-Mediated Ca 2+ Signals Confer Fibrogenesis in Human Atrial Fibrillation

(2010) Jianyang Du et al.   CIRCULATION RESEARCH

TRPM6 and TRPM7: A Mul-TRP-PLIK-Cation of Channel Functions

(2010) Loren W. Runnels   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Comparative gene expression analysis in mouse models for multiple sclerosis, Alzheimer's disease and stroke for identifying commonly regulated and disease-specific gene changes

(2010) Vivian Tseveleki et al.   GENOMICS

TRPM7 is essential for Mg2+ homeostasis in mammals

(2010) Lillia V. Ryazanova et al.   Nature Communications

Evidence that TRPM7 is required for breast cancer cell proliferation

(2009) Arnaud Guilbert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Calcium flickers steer cell migration

(2009) Chaoliang Wei et al.   NATURE

Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension

(2008) Rhian M. Touyz   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

PIP2 Is a Necessary Cofactor for Ion Channel Function: How and Why?

(2008) Byung-Chang Suh et al.   Annual Review of Biophysics

Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer

(2008) Byung Joo Kim et al.   CANCER SCIENCE

TRPM7 Ion Channels Are Required for Sustained Phosphoinositide 3-Kinase Signaling in Lymphocytes

(2008) Jaya Sahni et al.   Cell Metabolism

Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells

(2008) Thomas F.J. Wagner et al.   NATURE CELL BIOLOGY

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Massive Autophosphorylation of the Ser/Thr-Rich Domain Controls Protein Kinase Activity of TRPM6 and TRPM7

(2008) Kristopher Clark et al.   PLoS One

TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane

(2008) S. Brauchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of Trpm7 Disrupts Embryonic Development and Thymopoiesis Without Altering Mg2+ Homeostasis

(2008) J. Jin et al.   SCIENCE

Evolutionary determinants of divergent calcium selectivity of TRPM channels

(2007) Michael Mederos y Schnitzler et al.   FASEB JOURNAL