MAG-EPA and 17,18-EpETE target cytoplasmic signalling pathways to reduce short-term airway hyperresponsiveness

MAG-EPA resolves lung inflammation in an allergic model of asthma

(2013) C. Morin et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Eicosapentaenoic acid is converted via ω-3 epoxygenation to the anti-inflammatory metabolite 12-hydroxy-17,18-epoxyeicosatetraenoic acid

(2013) Tadafumi Kubota et al.   FASEB JOURNAL

Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone

(2012) George Gallos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Bronchial inflammation induced PKCζ over-expression: involvement in mechanical properties of airway smooth muscle

(2012) Caroline Morin et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Mechanisms of smooth muscle responses to inflammation

(2012) T. Shea-Donohue et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Inhibition of p21 Activated Kinase (PAK) Reduces Airway Responsiveness In Vivo and In Vitro in Murine and Human Airways

(2012) Wyn C. Hoover et al.   PLoS One

Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs

(2012) Dong-Soon Im   PROGRESS IN LIPID RESEARCH

Improved bioavailability of epoxyeicosatrienoic acids reduces TP-receptor agonist-induced tension in human bronchi

(2011) Farid Yannick Senouvo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The sentinel role of the airway epithelium in asthma pathogenesis

(2011) Stephen T. Holgate   IMMUNOLOGICAL REVIEWS

Levosimendan attenuates pulmonary vascular remodeling

(2011) M. Revermann et al.   INTENSIVE CARE MEDICINE

Regulation of Smooth Muscle Contraction by the Epithelium: Role of Prostaglandins

(2011) Ye Chun Ruan et al.   PHYSIOLOGY

Essential role of NF-κB and AP-1 transcription factors in TNF-α-induced TSLP expression in human airway smooth muscle cells

(2010) Naresh Singh Redhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

17,18-Epoxyeicosatetraenoic Acid Targets PPARγ and p38 Mitogen–Activated Protein Kinase to Mediate Its Anti-inflammatory Effects in the Lung

(2009) Caroline Morin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effects of cytokines on mechanical and epithelial bioelectric responses to methacholine and hyperosmolarity in guinea-pig airways: An in vitro study

(2009) Ugur B. Ismailoglu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gamma-Linolenic Acid Inhibits Inflammatory Responses by Regulating NF-κB and AP-1 Activation in Lipopolysaccharide-Induced RAW 264.7 Macrophages

(2009) Cheng-Sue Chang et al.   INFLAMMATION

An Atypical Protein Kinase C (PKC ) Plays a Critical Role in Lipopolysaccharide-Activated NF- B in Human Peripheral Blood Monocytes and Macrophages

(2009) X. Huang et al.   JOURNAL OF IMMUNOLOGY

Relaxing effects of 17(18)-EpETE on arterial and airway smooth muscles in human lung

(2008) Caroline Morin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Guinea Pig as an Animal Model for Asthma

(2008) Fabio Ricciardolo et al.   CURRENT DRUG TARGETS

Molecular mechanisms underlying airway smooth muscle contraction and proliferation: Implications for asthma

(2008) Girolamo Pelaia et al.   RESPIRATORY MEDICINE

EET Displays Anti-Inflammatory Effects in TNF-α–Stimulated Human Bronchi

(2007) Caroline Morin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting TNF-α: A novel therapeutic approach for asthma

(2007) Christopher Brightling et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY