Regulation of ClC-2 gating by intracellular ATP

Sequential interaction of chloride and proton ions with the fast gate steer the voltage-dependent gating in ClC-2 chloride channels

(2012) Jorge E. Sánchez-Rodríguez et al.   JOURNAL OF PHYSIOLOGY-LONDON

GlialCAM, a Protein Defective in a Leukodystrophy, Serves as a ClC-2 Cl− Channel Auxiliary Subunit

(2012) Elena Jeworutzki et al.   NEURON

Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy

(2011) Tara Klassen et al.   CELL

Binding of ATP to the CBS domains in the C-terminal region of CLC-1

(2011) Pang-Yen Tseng et al.   JOURNAL OF GENERAL PHYSIOLOGY

ATP Induces Conformational Changes in the Carboxyl-terminal Region of ClC-5

(2010) Leigh Wellhauser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Barttin Activates ClC-K Channel Function by Modulating Gating

(2010) M. Fischer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Structure of a Eukaryotic CLC Transporter Defines an Intermediate State in the Transport Cycle

(2010) Liang Feng et al.   SCIENCE

Intracellular regulation of human ClC-5 by adenine nucleotides

(2009) Giovanni Zifarelli et al.   EMBO REPORTS

Two novelCLCN2mutations accelerating chloride channel deactivation are associated with idiopathic generalized epilepsy

(2009) C��cile Saint-Martin et al.   HUMAN MUTATION

Isolation and Characterization of a High Affinity Peptide Inhibitor of ClC-2 Chloride Channels

(2009) Christopher H. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of ClC-1 and KATPchannels in action potential–firing fast-twitch muscle fibers

(2009) Thomas Holm Pedersen et al.   JOURNAL OF GENERAL PHYSIOLOGY

Channel-like slippage modes in the human anion/proton exchanger ClC-4

(2009) Alexi K. Alekov et al.   JOURNAL OF GENERAL PHYSIOLOGY

Voltage-dependent and -independent titration of specific residues accounts for complex gating of a ClC chloride channel by extracellular protons

(2009) María Isabel Niemeyer et al.   JOURNAL OF PHYSIOLOGY-LONDON

CLCN2 variants in idiopathic generalized epilepsy

(2009) Ailing Kleefuß-Lie et al.   NATURE GENETICS

Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains

(2008) Jennie Garcia-Olivares et al.   JOURNAL OF PHYSIOLOGY-LONDON