Article
Veterinary Sciences
Dragos Scarlet, Eleni Malama, Sophie Fischer, Barbara Knutti, Heinrich Bollwein
Summary: This study analyzed the effects of the inflammatory reaction on fertility of mares and the clinical uterine findings at the time of artificial insemination. The results showed that age, reproductive status, and cervical tone influenced mare fertility. Using cooled-stored semen and performing the artificial insemination after ovulation increased pregnancy rates. Intrauterine fluid accumulation 12 h after insemination decreased chances of pregnancy, while treatment with oxytocin could slightly improve fertility of affected mares. Age, reproductive status, and clinical findings are useful parameters for assessment of fertility in mares.
VETERINARY SCIENCES
(2023)
Article
Agriculture, Dairy & Animal Science
A. Husnain, U. Arshad, M. B. Poindexter, R. Zimpel, M. Nehme Marinho, M. C. Perdomo, P. Fan, K. C. Jeong, C. D. Nelson, I. M. Sheldon, J. J. Bromfield, J. E. P. Santos
Summary: The objective of this experiment was to study the effect of inducing endometrial inflammation by infusing utero-pathogenic bacteria on productive performance and reproduction in lactating cows. The results showed that induced endometrial inflammation compromised milk production and reproduction in cows.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
A. R. Guadagnin, L. K. Fehlberg, B. Thomas, Y. Sugimoto, I. Shinzato, F. C. Cardoso
Summary: This study aimed to investigate the effects of feeding rumen-protected lysine (RPL) prepartum and postpartum on reproductive performance, uterine health, and gene expression. The results showed that feeding RPL prepartum improved uterine immune status, but had no effect on days to first ovulation postpartum.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Andrea D'Agostino, Tommaso Di Palma, Stefano Cecchini Gualandi, Raffaele Boni
Summary: A new method based on fluorescence spectroscopy is proposed for diagnosing equine endometritis by measuring the hydrogen peroxide content in uterine cells, showing a high correlation with microscopic cytological technique with easy practicality and speed of execution.
Article
Veterinary Sciences
Gianluca Martini, Roberta Bucci, Salvatore Parrillo, Augusto Carluccio, Maria Carmela Pisu
Summary: A 3-year-old Main Coon cat with recurrent pyometra was treated with uterine drainage and flushing, due to its high reproductive value. After the surgery, the cat showed no recurrence and had a successful pregnancy.
VETERINARY SCIENCES
(2023)
Article
Agriculture, Dairy & Animal Science
Wenxiang Shen, Ayodele Olaolu Oladejo, Xiaoyu Ma, Wei Jiang, Juanshan Zheng, Bereket Habte Imam, Shengyi Wang, Xiaohu Wu, Xuezhi Ding, Baohua Ma, Zuoting Yan
Summary: This study found that Cl-amidine effectively alleviated the inflammatory response to LPS-induced endometritis in rats by inhibiting the formation of NETs. Therefore, Cl-amidine could be a potential candidate for the treatment of endometritis.
Article
Agriculture, Dairy & Animal Science
M. Ibrahim, M. S. Ferrer, R. E. Ellerbrock, E. Rollin
Summary: A study compared the effectiveness of collecting endometrial samples using a cytobrush and a cytotape, finding that cytotape samples had better quality and less blood contamination. There were no significant differences in terms of cellularity, neutrophil count, and other aspects between the two collection methods.
ANIMAL REPRODUCTION SCIENCE
(2021)
Review
Immunology
Sana Asif, Talha Umar, Zaima Umar, Huma Jamil, Huili Feng, Peipei Zhang, Saqib Umer
Summary: Endometritis is a significant factor in mare infertility, and miRNA plays a crucial role in regulating inflammatory responses. This review focuses on the pathomorphological findings in equine endometritis, the expression and effects of specific miRNAs (eca-miR-17, eca-miR-223, eca-miR-200a, eca-miR-155, and eca-miR-205) in endometritis, and the therapeutic potential of miRNAs in treating this condition. The study of these noncoding RNA molecules provides insights into the molecular mechanisms by which miRNAs regulate inflammation-related genes.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Article
Microbiology
Elizaveta Koroleva, Heidi Christa Steffen, Caylin Bosch, Leonard Flemming, Alfred Botha
Summary: This study investigated the physiology and potential pathogenicity of Corynebacterium uterequi in mares suffering from reproductive complications. It found that C. uterequi strains possessed virulence-associated characteristics and the ability to form weakly adherent biofilms, potentially leading to chronic infections. Further research is needed to establish C. uterequi as an equine pathogen and understand its role in pregnancy complications.
VETERINARY MICROBIOLOGY
(2022)
Article
Veterinary Sciences
Maria Eduarda Dias, Camila Azevedo Moni, Cassiane Elisabete Lopes, Fabiana Caroline Zempulski Volpato, Afonso Luis Barth, Franciele Maboni Siqueira
Summary: This article describes a case of reproductive failure in a 15-year-old Thoroughbred mare caused by the uncommon bacterium A. hippocoleae. The strain was isolated and identified by MALDI-TOF and 16 S rDNA sequencing, and found to be susceptible to several antimicrobial agents. The study highlights the importance of isolating and identifying infectious agents in cases of reproductive failure in mares.
EQUINE VETERINARY EDUCATION
(2023)
Article
Multidisciplinary Sciences
Jinfeng Wang, Zhanzhan Li, Xiuling Ma, Lifeng Du, Zhen Jia, Xue Cui, Liqun Yu, Jing Yang, Liwen Xiao, Bing Zhang, Huimin Fan, Fangqing Zhao
Summary: The study focuses on the comparative analysis of vaginal and uterine microbiota derived from women with chronic endometritis, and characterizes the microbial translocation in the female reproductive tract and its role in modulating uterine health through animal experiments. With advancing age, there is synchronous variation and increasing convergence of the uterine and vaginal microbiome.
NATURE COMMUNICATIONS
(2021)
Article
Medicine, Research & Experimental
Miaoxin Yang, Suyuan Liu, Jiangxue Cai, Xiaoxiao Sun, Chenxuan Li, Meiling Tan, Bin He
Summary: Bile acids exhibit anti-inflammatory properties by inhibiting the activation of the NLRP3 inflammasome, making them a potential novel therapeutic strategy for endometritis.
Article
Biochemistry & Molecular Biology
Lu Cao, Shouyang Gao, Junbao Liu, Junrong Wang, Rui Qin
Summary: Selenomethionine (SeMet) has protective effects on Escherichia coli-induced endometritis by attenuating inflammation and necroptosis, which is mediated by the PPAR-γ/NF-κB signaling pathway.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Reproductive Biology
Rebeca Martinez-Bovi, Maria Plaza-Davila, Juan Cuervo-Arango
Summary: The use of flunixin-meglumine during the critical period before ovulation leads to ovulatory failure and formation of haemorrhagic anovulatory follicles in mares. The effect of dexamethasone on ovulation blockage following hCG administration has not been determined. Dexamethasone treatment during the critical window did not block or delay ovulation, but resulted in longer inter-ovulatory intervals and reduced endometrial oedema.
Article
Veterinary Sciences
Bingke Wang, Jinbang Xiao, Yongjie Ma, Chuxi Gao, Hanbing Li, Yonghong Jia, Yaping Jin, Pengfei Lin
Summary: This study aimed to compare the effectiveness of the hormone program M+C with the Pre-OvSynch program. The results showed that the M+C program had significantly better pregnancy rates and reduced the number of artificial inseminations compared to the Pre-OvSynch program, while also significantly reducing open days.
FRONTIERS IN VETERINARY SCIENCE
(2022)