Journal
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
Volume 106, Issue 3, Pages 172-176Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.pestbp.2013.03.010
Keywords
Human head louse; Pediculus humanus capitis; Human body louse; Pediculus humanus humanus
Categories
Funding
- NIH/NHGRI
- NIH/NIAID [R01 AI045062-04A3, 1 R56AI081933-01A2]
- USDA - National Institute of Food and Agriculture [2009-51104-05780]
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Human lice represent a unique ectoparasitic relationship with humans. Head lice, which do not vector human diseases, exist in many human populations where they represent a considerable nuisance. However, body lice tend to appear when social economic conditions that allow opportunities for significantly reduced hygiene in individuals or populations and they vector human bacterial diseases. There are limited control options for human lice coupled with the emergence of pesticide resistance in insect populations. A better understanding of insect genomes has been proposed as a starting point for the development of novel insect control strategies. In this review, we summarize the findings of the body louse genome project, subsequent work, and its impact on new insights into human lice with the potential for long-term novel pest control strategies. RNAi is also discussed, including the potential for resistance using this strategy. (C) 2013 Published by Elsevier Inc.
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