Heterogeneity in primary tumors and corresponding metastases: could it provide us with any hints to personalize cancer therapy?

The heterogeneity of epithelial ovarian cancer

(2010) David M. Gershenson   CANCER

Patient-Derived First Generation Xenografts of Non-Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy

(2010) X. Dong et al.   CLINICAL CANCER RESEARCH

Prevalence and Heterogeneity of KRAS, BRAF, and PIK3CA Mutations in Primary Colorectal Adenocarcinomas and Their Corresponding Metastases

(2010) S. E. Baldus et al.   CLINICAL CANCER RESEARCH

Genetic heterogeneity and chromatin modifiers in renal clear cell carcinoma

(2010) Peter Staller   Future Oncology

Intratumor Heterogeneity and Precision of Microarray-Based Predictors of Breast Cancer Biology and Clinical Outcome

(2010) William T. Barry et al.   JOURNAL OF CLINICAL ONCOLOGY

Intratumoural cytogenetic heterogeneity of sporadic colorectal carcinomas suggests several pathways to liver metastasis

(2010) José María Sayagués et al.   JOURNAL OF PATHOLOGY

Discordance of Molecular Biomarkers Associated with Epidermal Growth Factor Receptor Pathway between Primary Tumors and Lymph Node Metastasis in Non-small Cell Lung Cancer

(2010) Sarah Park et al.   Journal of Thoracic Oncology

Quantum-dot-based immunofluorescent imaging of HER2 and ER provides new insights into breast cancer heterogeneity

(2010) Chuang Chen et al.   NANOTECHNOLOGY

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

(2010) S L Cooke et al.   ONCOGENE

Personalized cancer therapy using a patient-derived tumor tissue xenograft model: a translational field worthy of exploring further?

(2010) Ketao Jin et al.   Personalized Medicine

Genotypic Intratumoral Heterogeneity in Breast Carcinoma With HER2/neuAmplification

(2009) Matteo Brunelli et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant

(2009) F Molinari et al.   BRITISH JOURNAL OF CANCER

A comparison of EGFR and KRAS status in primary lung carcinoma and matched metastases

(2009) Sara E. Monaco et al.   HUMAN PATHOLOGY

PTEN Expression and KRAS Mutations on Primary Tumors and Metastases in the Prediction of Benefit From Cetuximab Plus Irinotecan for Patients With Metastatic Colorectal Cancer

(2009) Fotios Loupakis et al.   JOURNAL OF CLINICAL ONCOLOGY

Gene therapy as an adjuvant treatment for malignant gliomas: from bench to bedside

(2009) Isabelle M. Germano et al.   JOURNAL OF NEURO-ONCOLOGY

Intratumoral Heterogeneity for Expression of Tyrosine Kinase Growth Factor Receptors in Human Colon Cancer Surgical Specimens and Orthotopic Tumors

(2008) Toshio Kuwai et al.   AMERICAN JOURNAL OF PATHOLOGY

Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases

(2008) Argun Akcakanat et al.   CANCER

Intertumor and Intratumor NY-ESO-1 Expression Heterogeneity Is Associated with Promoter-Specific and Global DNA Methylation Status in Ovarian Cancer

(2008) A. Woloszynska-Read et al.   CLINICAL CANCER RESEARCH

Heterogeneity of Breast Cancer Metastases: Comparison of Therapeutic Target Expression and Promoter Methylation Between Primary Tumors and Their Multifocal Metastases

(2008) J. M. Wu et al.   CLINICAL CANCER RESEARCH

Tumor heterogeneity in ovarian cancer as demonstrated by in vitro chemoresistance assays

(2008) J.N. McAlpine et al.   GYNECOLOGIC ONCOLOGY

Evaluation of human brain tumor heterogeneity using multipleT1-based MRI signal weighting approaches

(2008) Manus J. Donahue et al.   MAGNETIC RESONANCE IN MEDICINE