Pharmacogenomics and adverse drug reactions

Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing

(2010) P Lenzini et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Will there be a role for genotyping in warfarin therapy?

(2010) Esteban Gandara et al.   CURRENT OPINION IN HEMATOLOGY

Warfarin Genotyping Reduces Hospitalization Rates

(2010) Robert S. Epstein et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Transporters in drug development: advancing on the Critical Path

(2010) Shiew-Mei Huang et al.   NATURE REVIEWS DRUG DISCOVERY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Drug-induced liver injury: past, present and future

(2010) Ann K Daly   PHARMACOGENOMICS

Genetic Polymorphism of Metabolic Enzymes P450 (CYP) as a Susceptibility Factor for Drug Response, Toxicity, and Cancer Risk

(2009) Nada Božina et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

The genetics of statin-induced myopathy

(2009) Abhijit Ghatak et al.   ATHEROSCLEROSIS

Novel Biomarkers of Acute Kidney Toxicity

(2009) F M Goodsaid et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The International Transporter Consortium: A Collaborative Group of Scientists From Academia, Industry, and the FDA

(2009) S-M Huang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genomic and proteomic approaches for predicting toxicity and adverse drug reactions

(2009) Feng Ge et al.   Expert Opinion on Drug Metabolism & Toxicology

The SLCO1B1*5Genetic Variant Is Associated With Statin-Induced Side Effects

(2009) Deepak Voora et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pharmacogenetics — Tailoring Treatment for the Outliers

(2009) Janet Woodcock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adverse Event Detection in Drug Development: Recommendations and Obligations Beyond Phase 3

(2008) Jesse A. Berlin et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Abacavir Hypersensitivity Reaction: an Update

(2008) Christine A Hughes et al.   ANNALS OF PHARMACOTHERAPY

Integration and use of biomarkers in drug development, regulation and clinical practice: a US regulatory perspective

(2008) Shashi Amur et al.   Biomarkers in Medicine

Is This the Drug or Dose for You?: Impact and Consideration of Ethnic Factors in Global Drug Development, Regulatory Review, and Clinical Practice

(2008) S-M Huang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

(2008) Jessica L. Mega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility

(2008) A R Hughes et al.   PHARMACOGENOMICS JOURNAL

Pharmacogenomic Biomarker Information in Drug Labels Approved by the United States Food and Drug Administration: Prevalence of Related Drug Use

(2008) Felix W Frueh et al.   PHARMACOTHERAPY