Journal
PEPTIDES
Volume 34, Issue 1, Pages 51-56Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.peptides.2011.08.005
Keywords
Cardioacceleratory; Kynurenine; Tryptophan; Heart; Lipid
Funding
- Natural Sciences and Engineering Research Council of Canada
- National Research Foundation of the Republic of South Africa [FA 2007021300002, IFR 2008071500048]
- University of Cape Town (University Research Council)
Ask authors/readers for more resources
The corpora cardiaca of the Vietnamese stick insect, Baculum extradentatum, contain a member of the adipokinetic hormone/red pigment-concentrating hormone/hypertrehalosemic hormone (AKH/RPCH/HrTH) family of peptides whose sequence is identical to that originally described for the Indian stick insect, Carausius morosus. This decapeptide, Carmo-HrTH-II (pELTFTPNWGTa), has both hypertrehalosemic and cardioacceleratory activity in B. extradentatum, and hyperlipaemic activity in locusts. Reversed-phase high performance liquid chromatography (RP-HPLC) of corpora cardiaca extract followed by MALDI-TOF MS/MS also revealed a novel modification of a second peptide in B. extradentatum: the tryptophan residue at position 8 is post-translationally modified to kynurenine. (C) 2011 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available