Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies

Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches

(2015) Andrew J. Copas et al.   Trials

Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014

(2015) Emma Beard et al.   Trials

Pressure ulcer multidisciplinary teams via telemedicine: a pragmatic cluster randomized stepped wedge trial in long term care

(2014) Anita Stern et al.   BMC HEALTH SERVICES RESEARCH

Evaluation of a structured goal planning and tailored follow-up programme in rehabilitation for patients with rheumatic diseases: protocol for a pragmatic, stepped-wedge cluster randomized trial

(2014) Ingvild Kjeken et al.   BMC MUSCULOSKELETAL DISORDERS

The practice of ‘doing’ evaluation: lessons learned from nine complex intervention trials in action

(2014) Joanna Reynolds et al.   Implementation Science

Launching a salt substitute to reduce blood pressure at the population level: a cluster randomized stepped wedge trial in Peru

(2014) Antonio Bernabe-Ortiz et al.   Trials

The prevention and reduction of weight loss in an acute tertiary care setting: protocol for a pragmatic stepped wedge randomised cluster trial (the PRoWL project)

(2013) Alison L Kitson et al.   BMC HEALTH SERVICES RESEARCH

Protocol-driven primary care and community linkages to improve population health in rural Zambia: the Better Health Outcomes through Mentoring and Assessment (BHOMA) project

(2013) Jeffrey SA Stringer et al.   BMC HEALTH SERVICES RESEARCH

Stores Healthy Options Project in Remote Indigenous Communities (SHOP@RIC): a protocol of a randomised trial promoting healthy food and beverage purchases through price discounts and in-store nutrition education

(2013) Julie Brimblecombe et al.   BMC PUBLIC HEALTH

Evaluation of an interactive program for preventing adverse drug events in primary care: study protocol of the InPAct cluster randomised stepped wedge trial

(2013) Maud Keriel-Gascou et al.   Implementation Science

A multifaceted strategy using mobile technology to assist rural primary healthcare doctors and frontline health workers in cardiovascular disease risk management: protocol for the SMARTHealth India cluster randomised controlled trial

(2013) Devarsetty Praveen et al.   Implementation Science

Effect of improved tuberculosis screening and isoniazid preventive therapy on incidence of tuberculosis and death in patients with HIV in clinics in Rio de Janeiro, Brazil: a stepped wedge, cluster-randomised trial

(2013) Betina Durovni et al.   LANCET INFECTIOUS DISEASES

Community resource centres to improve the health of women and children in Mumbai slums: study protocol for a cluster randomized controlled trial

(2013) Neena Shah More et al.   Trials

Pro’s and con’s of the stepped wedge design in cluster randomised trials of quality improvement interventions: two current examples

(2013) Tobias Dreischulte et al.   Trials

Researchers’ perceptions of ethical challenges in cluster randomized trials: a qualitative analysis

(2013) Andrew D McRae et al.   Trials

The impact of an exercise physiologist coordinated resistance exercise program on the physical function of people receiving hemodialysis: a stepped wedge randomised control study

(2013) Paul N Bennett et al.   BMC Nephrology

The effect of training doctors in communication skills on women’s satisfaction with doctor–woman relationship during labour and delivery: a stepped wedge cluster randomised trial in Damascus

(2013) Hyam N Bashour et al.   BMJ Open

In search of social equipoise

(2013) M. Petticrew et al.   BMJ-British Medical Journal

The Ottawa Statement on the ethical design and conduct of cluster randomised trials: precis for researchers and research ethics committees

(2013) M. Taljaard et al.   BMJ-British Medical Journal

Quasi-experimental trial of diabetes Self-Management Automated and Real-Time Telephonic Support (SMARTSteps) in a Medicaid managed care plan: study protocol

(2012) Neda Ratanawongsa et al.   BMC HEALTH SERVICES RESEARCH

The Devon Active Villages Evaluation (DAVE) trial: Study protocol of a stepped wedge cluster randomised trial of a community-level physical activity intervention in rural southwest England

(2012) Emma Solomon et al.   BMC PUBLIC HEALTH

Mixed methods evaluation of targeted case finding for cardiovascular disease prevention using a stepped wedged cluster RCT

(2012) Tom Marshall et al.   BMC PUBLIC HEALTH

Universal HIV testing in London tuberculosis clinics: a cluster randomised controlled trial

(2012) Anjana Roy et al.   EUROPEAN RESPIRATORY JOURNAL

A cluster randomised stepped wedge trial to evaluate the effectiveness of a multifaceted information technology-based intervention in reducing high-risk prescribing of non-steroidal anti-inflammatory drugs and antiplatelets in primary medical care: The DQIP study protocol

(2012) Tobias Dreischulte et al.   Implementation Science

The effect of a complementary e-learning course on implementation of a quality improvement project regarding care for elderly patients: a stepped wedge trial

(2012) Lotte Van de Steeg et al.   Implementation Science

Use of the stepped wedge design cannot be recommended: A critical appraisal and comparison with the classic cluster randomized controlled trial design

(2012) Daniel Kotz et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

The Feedback Intervention Trial (FIT) — Improving Hand-Hygiene Compliance in UK Healthcare Workers: A Stepped Wedge Cluster Randomised Controlled Trial

(2012) Christopher Fuller et al.   PLoS One

What is the role and authority of gatekeepers in cluster randomized trials in health research?

(2012) Antonio Gallo et al.   Trials

The longitudinal prevalence of MRSA in care home residents and the effectiveness of improving infection prevention knowledge and practice on colonisation using a stepped wedge study design

(2012) C Horner et al.   BMJ Open

The case study approach

(2011) Sarah Crowe et al.   BMC Medical Research Methodology

Act In case of Depression: The evaluation of a care program to improve the detection and treatment of depression in nursing homes. Study Protocol

(2011) Debby L Gerritsen et al.   BMC Psychiatry

A knowledge translation collaborative to improve the use of therapeutic hypothermia in post-cardiac arrest patients: protocol for a stepped wedge randomized trial

(2011) Katie N Dainty et al.   Implementation Science

Implementation Science for the US Presidentʼs Emergency Plan for AIDS Relief (PEPFAR)

(2011) Nancy S Padian et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Systematic review of stepped wedge cluster randomized trials shows that design is particularly used to evaluate interventions during routine implementation

(2011) Noreen D. Mdege et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Equipoise and the Dilemma of Randomized Clinical Trials

(2011) Franklin G. Miller et al.   NEW ENGLAND JOURNAL OF MEDICINE

Does clinical equipoise apply to cluster randomized trials in health research?

(2011) Ariella Binik et al.   Trials

Ethical issues posed by cluster randomized trials in health research

(2011) Charles Weijer et al.   Trials

When is informed consent required in cluster randomized trials in health research?

(2011) Andrew D McRae et al.   Trials

Impact of a multifaceted program to prevent postoperative delirium in the elderly: the CONFUCIUS stepped wedge protocol

(2011) Christelle Mouchoux et al.   BMC Geriatrics

Intervenção comunitária para prevenção de acidentes de trânsito entre trabalhadores ciclistas

(2010) Giancarlo Bacchieri et al.   REVISTA DE SAUDE PUBLICA

Antiretroviral therapy in antenatal care to increase treatment initiation in HIV-infected pregnant women: a stepped-wedge evaluation

(2009) William P Killam et al.   AIDS

Ethical challenges in cluster randomized controlled trials: experiences from public health interventions in Africa and Asia

(2009) David Osrin et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Developing and evaluating complex interventions: the new Medical Research Council guidance

(2008) Peter Craig et al.   BMJ-British Medical Journal