Article
Pharmacology & Pharmacy
Qiqi Zhu, Songyi Zhou, Zina Wen, Huitao Li, Bingwu Huang, Yier Chen, Xiaoheng Li, Han Lin, Yiyan Wang, Ren-Shan Ge
Summary: The study reported the impact of xylene exposure on Leydig cell development in male rats during puberty, indicating that xylene can reduce testosterone levels, decrease the number of Leydig cells, and down-regulate gene expression levels.
Article
Environmental Sciences
Tianyu Zhao, Kai Triebner, Iana Markevych, Marie Standl, Hicran Altug, Kees de Hoogh, Tamara Schikowski, Dietrich Berdel, Sibylle Koletzko, Carl-Peter Bauer, Andrea von Berg, Dennis Nowak, Joachim Heinrich
Summary: The study found no significant associations between long-term exposure to air pollutants and pubertal development based on sex hormone concentrations among 10-year-old children. More longitudinal studies are needed to further assess this association due to the limited number of current studies on this topic.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Francesca Castiello, Beatriz Suarez, Andrea Beneito, Maria-Jose Lopez-Espinosa, Loreto Santa-Marina, Aitana Lertxundi, Adonina Tardon, Isolina Riano-Galan, Maribel Casas, Martine Vrijheid, Nicolas Olea, Mariana F. Fernandez, Carmen Freire
Summary: This study examined the associations between urinary metabolites of non-persistent pesticides and pubertal development in children from urban and rural areas in Spain. The results showed that higher concentrations of certain pesticide metabolites were associated with increased odds of pubertal development, especially in girls, and BMI may modify these associations.
ENVIRONMENTAL POLLUTION
(2023)
Article
Neurosciences
Madison H. Fung, Elizabeth Heinrichs-Graham, Brittany K. Taylor, Michaela R. Frenzel, Jacob A. Eastman, Yu-Ping Wang, Vince D. Calhoun, Julia M. Stephen, Tony W. Wilson
Summary: Puberty is a period of significant hormonal fluctuations that can influence the structural and functional changes in the developing brain. This study used MEG technology to investigate the impact of pubertal hormones on motor-related oscillations in 69 youths. The findings revealed that pubertal hormones have complex effects on beta event-related desynchronization and highlight the continued development of motor cortical dynamics during puberty.
Article
Neurosciences
Madison H. Fung, Raeef L. Rahman, Brittany K. Taylor, Michaela R. Frenzel, Jacob A. Eastman, Yu-Ping Wang, Vince D. Calhoun, Julia M. Stephen, Tony W. Wilson
Summary: The adolescent brain undergoes significant changes in structure and function. This study found that pubertal hormones may modulate the development of neural oscillatory activity, especially in visuospatial processing and attention functions during puberty.
HUMAN BRAIN MAPPING
(2022)
Article
Environmental Sciences
Jane S. Burns, Oleg Sergeyev, Mary M. Lee, Paige L. Williams, Lidia Minguez-Alarcon, Bora Plaku-Alakbarova, Sergey Sokolov, Sergey Kovalev, Holger M. Koch, Albert T. Lebedev, Russ Hauser, Susan A. Korrick
Summary: This study examined the association between phthalate metabolite concentrations in prepubertal urine and age at pubertal onset in Russian boys. The results showed that boys with higher concentrations of phthalate metabolites had later pubertal onset, possibly due to disruption of androgen-dependent biological pathways.
ENVIRONMENTAL RESEARCH
(2022)
Article
Endocrinology & Metabolism
Xinyi Liang, Ke Huang, Guangping Dong, Ruimin Chen, Shaoke Chen, Rongxiu Zheng, Chunlin Wang, Haiyan Wei, Bingyan Cao, Yan Liang, Hui Yao, Zhe Su, Mireguli Maimaiti, Feihong Luo, Pin Li, Min Zhu, Hongwei Du, Yu Yang, Lanwei Cui, Shuting Si, Guannan Bai, Yunxian Yu, Er-Gang Wang, Paul L. Hofman, Junfen Fu
Summary: Over the past decade, pubertal development has been occurring earlier in Chinese children. The age for breast development in girls is 9.65 years and for testicular volume ≥ 4 mL in boys is 10.65 years. Obesity and overweight are associated with a higher risk for early puberty onset.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Psychology, Developmental
Alithe L. Van den Akker, Daniel A. Briley, Andrew D. Grotzinger, Jennifer L. Tackett, Elliot M. Tucker-Drob, K. Paige Harden
Summary: Studies have shown that in early adolescence, levels of conscientiousness and agreeableness may temporarily decrease while levels of neuroticism increase, potentially due to pubertal development. Pubertal development can impact the maturity of personality traits, with small associations found between pubertal development and lower levels of conscientiousness and agreeableness.
DEVELOPMENTAL PSYCHOLOGY
(2021)
Review
Endocrinology & Metabolism
Alessandra Mancini, John C. Magnotto, Ana Paula Abreu
Summary: Puberty is a transitional period from childhood to adulthood, characterized by physiological and psychological changes for sexual maturation and fertility. The onset of puberty is regulated by genetic, nutritional, environmental, and socio-economic factors, and approximately 50-80% of the variation in pubertal timing is genetically determined. Insights into the genetic control of pubertal onset have been obtained through large populational studies and patient cohort-based studies, shedding light on potential mechanisms involved.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Reproductive Biology
Hiruni R. Wijesena, Brittney N. Keel, Dan J. Nonneman, Robert A. Cushman, Clay A. Lents
Summary: Through clustering analysis of multi-tissue expression data, it was found that the reasons for poor development in young gilts include reduced expression of key genes for gonadotropin secretion in the hypothalamus and reduced expression of genes affecting follicle development in the ovary.
BIOLOGY OF REPRODUCTION
(2023)
Article
Environmental Sciences
J. S. Burns, J. R. Bather, O. Sergeyev, M. M. Lee, S. A. Korrick, S. Sokolov, S. Kovalev, H. M. Koch, A. T. Lebedev, L. Minguez-Alarcon, R. Hauser, P. L. Williams
Summary: A study on Russian boys found that prepubertal urinary phthalate metabolite concentrations were associated with trajectories of pubertal progression. By collecting and analyzing demographic information and urine samples from boys aged 8-19, it was found that certain phthalate metabolite concentrations were associated with slower or faster pubertal progression trajectories.
ENVIRONMENTAL RESEARCH
(2023)
Review
Public, Environmental & Occupational Health
Zorimar Rivera-Nunez, Carolyn W. Kinkade, Yingting Zhang, Amber Rockson, Elisa V. Bandera, Adana A. M. Llanos, Emily S. Barrett
Summary: Studies have shown that prenatal monoethyl phthalate (MEP) concentrations may be associated with slightly earlier timing of puberty, including age at menarche. However, findings on peri-pubertal phthalate exposures and pubertal outcomes were inconsistent, as were studies on prenatal and peri-pubertal phenol exposures. Limited research has been conducted on parabens in relation to girls' pubertal development.
CURRENT ENVIRONMENTAL HEALTH REPORTS
(2022)
Article
Environmental Sciences
Carmen Freire, Francesca Castiello, Maria-Jose Lopez-Espinosa, Andrea Beneito, Aitana Lertxundi, Alba Jimeno-Romero, Martine Vrijheid, Maribel Casas
Summary: Prenatal exposure to certain phthalates is associated with pubertal development, particularly earlier puberty in boys with normal weight and girls with overweight/obesity.
ENVIRONMENTAL RESEARCH
(2022)
Review
Endocrinology & Metabolism
Giuseppa Patti, Marco Scaglione, Nadia Gabriella Maiorano, Giulia Rosti, Maria Teresa Divizia, Tiziana Camia, Elena Lucia De Rose, Alice Zucconi, Emilio Casalini, Flavia Napoli, Natascia Di Iorgi, Mohamad Maghnie
Summary: In this narrative review, the authors summarized the available data on puberty and gonadal function in Noonan syndrome (NS) subjects and discussed the role of the RAS/mitogen-activated protein kinase (MAPK) signalling pathway in fertility. NS patients tend to have a delay in puberty onset compared to healthy children, and males with NS are at risk of gonadal dysfunction due to factors including cryptorchidism, the MAP/MAPK pathway, and genetics. Long-term studies on a large cohort of NS patients are needed to better understand the impact of delayed puberty on adult height, metabolic profile, and well-being. Genetic counseling and fertility-related issues are crucial.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Io Ieong Chan, Man Ki Kwok, C. Mary Schooling
Summary: This study investigated the association between pubertal maturation timing and adulthood blood pressure using Mendelian randomization (MR) with larger genome-wide association studies (GWAS) data. The results showed a significant correlation between pubertal maturation timing and adulthood blood pressure, independent of childhood body mass index (BMI).
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)