Review
Multidisciplinary Sciences
Melisa Medina-Rivera, Elizabeth Centeno-Tablante, Julia L. Finkelstein, Pura Rayco-Solon, Juan Pablo Pena-Rosas, Maria N. Garcia-Casal, Lisa Rogers, Pratiwi Ridwan, Sabrina Sales Martinez, Joyce Andrade, Alexander J. Layden, Juan Chang, Mildred P. Zambrano, Kate Ghezzi-Kopel, Saurabh Mehta
Summary: This systematic review examined the presence of EBOV in breast milk and the risk of viral transmission to infants through breastfeeding. The study found that most EBOV-positive breast milk samples led to EBOV infection in breastfed infants, resulting in fatality. However, due to the presence of EBOV in other bodily fluids, it is inconclusive whether breast milk is the main route of transmission.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2021)
Article
Nursing
Katherine R. Standish, Ginny Combs, Marcy Mcmahon, Cheryl Slater, Lisa Zani, Christina Pindar, Karol Serafin, Margaret G. Parker, Barbara L. Philipp
Summary: Late preterm infants have lower breastfeeding rates and there are few interventions or guidelines for managing them in non-intensive nursery settings. This study developed and implemented an interdisciplinary breastfeeding support program, which increased nurses' attentiveness and confidence in caring for late preterm infants. However, well-designed clinical studies are needed to identify effective breastfeeding support practices.
JOURNAL OF HUMAN LACTATION
(2023)
Article
Medicine, General & Internal
Manuela Arbune, Alina Mihaela Calin, Alina Viorica Iancu, Caterina Nela Dumitru, Anca Adriana Arbune
Summary: This study assesses the effectiveness of a perinatal infection prevention program in a single center in southeast Romania. The study found that there was zero transmission rate from HIV-positive mothers to living children, but neonatal mortality, preterm birth, and birth defects were still high.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Jane R. Millar, Isabella Fatti, Noxolo Mchunu, Nomonde Bengu, Nicholas E. Grayson, Emily Adland, David Bonsall, Moherndran Archary, Philippa C. Matthews, Thumbi Ndung'u, Philip Goulder
Summary: The global incidence of pregnancy among women with perinatal HIV infection is increasing, leading to a growing risk of second-generation mother-to-child HIV transmission. Clinical outcomes for infants born in this context were found to be poor, with mothers facing difficulties in administering antiretroviral therapy to their infants.
Review
Obstetrics & Gynecology
Anne Esther Njom Nlend
Summary: This literature review examines the issue of HIV transmission through breastfeeding and proposes strategies to address the key challenges, including improving testing and treatment adherence, strengthening care for mother-baby pairs, and implementing pre-exposure prophylaxis for high-risk women.
INTERNATIONAL JOURNAL OF WOMENS HEALTH
(2022)
Article
Food Science & Technology
Lan Yang, Hafiz Arbab Sakandar, Zhihong Sun, Heping Zhang
Summary: This study reviewed the characteristics, influencing factors, and effects of pregnant women on offspring, the establishment and development of intestinal microbiota in infants, and the significance of mother-to-infant transmission. The aim was to provide new research impetus on the establishment of intestinal microbiota in infants.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Biochemistry & Molecular Biology
Lukas Cerveny, Padma Murthi, Frantisek Staud
Summary: HIV infection has adverse effects on pregnancy outcomes, necessitating antiretroviral treatment for pregnant women to reduce mother-to-child transmission. However, uncertainties remain regarding changes in drug metabolism during pregnancy and the long-term effects of antiretrovirals on fetuses.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2021)
Review
Microbiology
Carolina Rosadas, Graham P. Taylor
Summary: This systematic review examined interventions to prevent HTLV-1 mother-to-child transmission and found that avoiding breastfeeding is an effective strategy with a transmission prevention rate of 85%. It is currently recommended in several countries and regions.
Review
Public, Environmental & Occupational Health
Maria-Lauretta Orji, Oluchukwu Cecilia Oyim-Elechi, Joseph Agboeze, Matthew Igwe Nwali
Summary: This article reports four cases of HIV-infected infants claimed to be delivered by HIV-negative mothers. These mothers are above 40 years old and have been infertile for 9 to 18 years in marriage. The cryptic pregnancy scam was not confirmed by pregnancy tests or obstetric scans. HIV infection in the infants was only diagnosed after birth. Conclusion: The cryptic pregnancy scam in Nigeria undermines the efforts made in HIV prevention and control. Desperate infertile women are deceived into believing that they are pregnant, and babies are bought and given to them on the specified delivery date. These mothers never received proper prenatal care and were not screened for HIV. Awareness and education on the harm of cryptic pregnancy scam are necessary.
JOURNAL OF PUBLIC HEALTH
(2023)
Article
Infectious Diseases
An-qun Hu, Qian-ying Cai, Miao Zhang, Hai-yan Liu, Tian-lei Wang, Wen-hui Han, Qing Li, Wei Fan, Yi-jie Li, Yi-ning He, Ying-jie Zheng
Summary: This study investigated different types of hepatitis B infection among mothers and infants, evaluating the effectiveness of vaccination against hepatitis B infection. The refinement of classification based on transmission types improved the estimate of vaccine effectiveness, particularly for certain types of transmission.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Nutrition & Dietetics
Dominick J. Lemas, Xinsong Du, Bethany Dado-Senn, Ke Xu, Amanda Dobrowolski, Marina Magalhaes, Juan J. Aristizabal-Henao, Bridget E. Young, Magda Francois, Lindsay A. Thompson, Leslie A. Parker, Josef Neu, Jimena Laporta, Biswapriya B. Misra, Ismael Wane, Samih Samaan, Timothy J. Garrett
Summary: This study aims to identify unique metabolites that may impact infant health outcomes by analyzing the metabolome of human and bovine milk at 2 weeks of life. The results showed that more than 80% of the milk metabolome is shared between human and bovine milk during early lactation. These findings highlight untargeted metabolomics as a potential strategy to identify unique and shared metabolites in bovine and human milk that may relate to and impact infant health outcomes.
Review
Infectious Diseases
Anna L. Funk, Ying Lu, Kyoko Yoshida, Tianshuo Zhao, Pauline Boucheron, Judith van Holten, Roger Chou, Marc Bulterys, Yusuke Shimakawa
Summary: Through analyzing 129 studies, we found that peripartum antiviral prophylaxis can significantly reduce the risk of HBV mother-to-child transmission, especially when using tenofovir disoproxil fumarate. There was no significant increase in any infant or maternal safety risks.
LANCET INFECTIOUS DISEASES
(2021)
Article
Immunology
Jesse F. Mangold, Ria Goswami, Ashley N. Nelson, David R. Martinez, Genevieve G. Fouda, Sallie R. Permar
Summary: While widespread availability of antiretroviral therapy has greatly reduced HIV mother-to-child transmission, progress towards global targets for pediatric HIV infections has stalled at a high estimate. Additional strategies beyond maternal antiretroviral therapy are needed to eliminate MTCT of HIV.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Article
Immunology
Jesse F. Mangold, Ria Goswami, Ashley N. Nelson, David R. Martinez, Genevieve G. Fouda, Sallie R. Permar
Summary: The widespread availability of antiretroviral therapy among pregnant women living with HIV has significantly reduced the rate of mother-to-child transmission of the virus globally. However, progress towards reducing new pediatric HIV infections has plateaued at a high level. Additional strategies beyond expanding maternal antiretroviral therapy will be needed to eliminate mother-to-child transmission of HIV.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Article
Infectious Diseases
Joseph Simbaya, Patricia Funjika, Arthur Moonga, John Mwale, Chipepo Kankasa
Summary: The study successfully estimated MTCT rates using infant testing in Zambia, with findings showing that most mothers of HIV-exposed infants attended ANC visits more than two times and exclusive breastfeeding rates decreased with infant age.
BMC INFECTIOUS DISEASES
(2021)
