Article
Oncology
Subha Perni, Beverly Moy, Ryan D. Nipp
Summary: The study found disparities in phase 1 versus phase 2/3 trial enrollment, with Black, Hispanic/Latino, and male patients being less likely to enroll in phase 1 trials compared to White patients. The findings suggest a need for targeted interventions to improve access to and education about phase 1 trials for Black and Hispanic/Latino patients.
Article
Obstetrics & Gynecology
Jayeon Kim, Brian W. Whitcomb, Brian Kwan, David Zava, Patrick M. Sluss, Andrew Dietz, Ksenya Shliakhtsitsava, Sally A. D. Romero, Loki Natarajan, H. Irene Su
Summary: There was no association found between psychosocial stress and ovarian function in adolescent and young adult cancer survivors.
HUMAN REPRODUCTION
(2021)
Article
Oncology
Mariam F. Eskander, Lindsay Gil, Eliza W. Beal, Yaming Li, Ahmad Hamad, Bridget Oppong, Samilia Obeng-Gyasi, Allan Tsung
Summary: The study found that age, race, insurance, and geography are barriers to clinical trial enrollment for pancreatic cancer patients. Despite an overall increase in enrollment, Black patients and patients on Medicaid remain underrepresented. Social determinants of health are still associated with clinical trial enrollment after adjusting for cancer-specific factors, suggesting the need for targeted interventions.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Medicine, General & Internal
Cristian Ochoa-Arnedo, Joan Carles Medina, Aida Flix-Valle, Dimitra Anastasiadou
Summary: This study aims to evaluate the effectiveness of an e-health platform with integrated and stepped psychosocial services compared to usual psychosocial care, as well as examine its cost-utility. It involves a multicentre randomised controlled trial with primary outcomes including number of clinical cases detected, waiting time from detection to intervention, and successfully treated cases at different steps. Findings will be disseminated through peer-reviewed journals, reports, conferences, workshops, and media press releases.
Article
Medicine, General & Internal
Meltem Dogan, Gerrit Hirschfeld, Markus Blankenburg, Michael Fruhwald, Rosemarie Ahnert, Sarah Braun, Ursula Marschall, Ingo Pfenning, Boris Zernikow, Julia Wager
Summary: This study evaluated the effectiveness of a psychosocial aftercare (PAC) program for pediatric patients with severe chronic pain, showing that PAC improved pain-related and emotional parameters during the 6 months after discharge from IIPT. The randomized clinical trial was conducted at 3 pediatric specialized tertiary care pain centers in Germany, highlighting the benefits of the PAC intervention for improving patient outcomes.
Article
Multidisciplinary Sciences
Cameron Bieganek, Constantin Aliferis, Sisi Ma
Summary: Clinical trials often face the challenge of poor recruitment, resulting in wasted resources. This study utilized a large dataset and machine learning methods to successfully predict the recruitment rate of clinical trials. The findings revealed that study design has a significant impact on recruitment, providing valuable insights for decision-making in clinical trials.
Article
Multidisciplinary Sciences
Grace Yao, Jin-Shei Lai, Sofia F. Garcia, Susan Yount, David Cella
Summary: This study used the PROMIS Psychosocial Illness Impact banks to explore the psychosocial impacts on cancer survivors. The results showed that survivors reported stronger positive impacts than negative impacts, and age, gender, education, and family income influenced the psychosocial impacts reported by survivors.
SCIENTIFIC REPORTS
(2023)
Article
Health Care Sciences & Services
Elizabeth J. Adams, David Tallman, Marcy L. Haynam, Larissa Nekhlyudov, Maryam B. Lustberg
Summary: This study presents a unique methodology to analyze the psychosocial experiences of survivors of gynecological cancer using large amounts of data from internet-based platforms. The study found that survivors frequently discussed the role of friends and family in care, fatigue, the effect of cancer on interpersonal relationships, and health insurance status. The findings contribute valuable insights into the experiences of patients and can be applied to other patient populations.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Clinical Neurology
Suzanne E. Schindler, Yan Li, Melody Li, Alyssa Despotis, Ethan Park, Liberty Vittert, Barton H. Hamilton, Kyle B. Womack, Benjamin Saef, David M. Holtzman, John C. Morris, Randall J. Bateman, Mahendra R. Gupta
Summary: This study developed a web-based application to model the time and financial cost of screening for Alzheimer's disease (AD) clinical trials. The results showed that incorporating an AD blood test into the screening process can reduce the time and financial cost of trial enrollment, and improvements in test accuracy have only minor impact on savings.
ALZHEIMERS & DEMENTIA
(2023)
Article
Oncology
Annekathrin Sender, Michael Friedrich, Katja Leuteritz, Erik Stuckenberg, Diana Richter, Yve Stoebel-Richter, Florian Lordick, Kristina Geue
Summary: This study systematically assessed the awareness of, utilization of and satisfaction with psychosocial care for adolescents and young adult (AYA) cancer survivors in aftercare. The results showed that survivors who were aware of psychosocial services were more likely to use them and expressed satisfaction with their use. Female gender and high anxiety were identified as common factors associated with the utilization of psychosocial services.
Article
Oncology
Elizabeth J. Siembida, Holli A. Loomans-Kropp, Irene Tami-Maury, David R. Freyer, Lillian Sung, Howland E. Crosswell, Brad H. Pollock, Michael E. Roth
Summary: This study examines the patterns of barriers and facilitators between high- and low-enrolling community-based clinics for AYA patients with cancer. High-enrolling clinics face more barriers downstream in the enrollment process, such as physician gatekeeping, while low-enrolling clinics struggle with earlier steps in the CCT enrollment process, such as identifying eligible trials. These findings highlight the need for multi-level, tailored interventions to improve AYA enrollment in the community setting.
Article
Oncology
Nicole Cameron, Kirsty Ross, Don Baken, David Bimler
Summary: The study found that themes such as personal privacy and controlled sharing of information, independence, identity formation, positivity, acknowledgment of cancer versus being treated normally, and receiving support instead of supporting others have a significant impact on interactions and development of AYA cancer survivors. These themes changed over a 1-year follow-up period, highlighting the evolving nature of social interactions and developmental effects of cancer.
Article
Pediatrics
Elliott Mark Weiss, Katherine F. Guttmann, Aleksandra E. Olszewski, Brooke E. Magnus, Sijia Li, Scott Y. H. Kim, Anita R. Shah, Sandra E. Juul, Yvonne W. Wu, Kaashif A. Ahmad, Ellen Bendel-Stenzel, Natalia A. Isaza, Andrea L. Lampland, Amit M. Mathur, Rakesh Rao, David Riley, David G. Russell, Zeynep N. Salih, Carrie B. Torr, Joern-Hendrik Weitkamp, Uchenna E. Anani, Taeun Chang, Juanita Dudley, John Flibotte, Erin M. Havrilla, Alexandra C. O'Kane, Krystle Perez, Brenda J. Stanley, Seema K. Shah, Benjamin S. Wilfond
Summary: The study revealed that the parental experience of recruitment varied by enrollment status. Parents who declined to enroll preferred to be approached by clinical team members rather than research team members, while enrolled parents more frequently reported positive initial impressions. Many parents in both groups made their decision early in the recruitment process.
JOURNAL OF PEDIATRICS
(2021)
Article
Immunology
Stephen M. Bart, John J. Farley, Shukal Bala, Thushi Amini, Edward Cox
Summary: As drug development becomes more globalized, geographical recruitment trends for recent antibacterial clinical trials vary by indication, but demographic characteristics and microbiology are broadly similar across regions, alleviating concerns about generalizability due to shifting enrollment trends.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Oncology
Karen Y. Y. Wonders, Kathryn Schmitz, Robert Wise, Ronald Hale
Summary: The study found that providing individualized exercise programs for early-stage breast cancer patients can significantly improve their fitness parameters and decrease healthcare utilization.
JCO ONCOLOGY PRACTICE
(2022)
