Article
Nutrition & Dietetics
Agata Witczak, Anna Pohorylo, Hassan Abdel-Gawad
Summary: The study assessed the safety of infants related to endocrine-disrupting organochlorine pesticides (OCP) in breast milk. It was found that certain dietary habits of pregnant mothers could affect the levels of OCP compounds in breast milk. The consumption of specific food products, such as pork, beef, poultry, eggs, and dairy, was linked to increased pesticide residues in breast milk.
Article
Nutrition & Dietetics
Yifan Zhang, Xiaoxu Zhang, Lijuan Mi, Chuangang Li, Yiran Zhang, Ran Bi, Jinzhu Pang, Yixuan Li
Summary: Breast milk is essential for infants as it provides the necessary nutrients and acquired immunity in the first month. The composition of breast milk protein varies with lactation stage, with colostrum containing the most characteristic proteins. The protein expression in breast milk undergoes significant changes between day 3 and day 14 and stabilizes after 14 days.
Article
Pediatrics
Chitmandeep Josan, Samantha Shiplo, Gerhard Fusch, Sandeep Raha, Alison K. Shea
Summary: This study investigates the effects of maternal cannabis use on the levels of macronutrients and bioactive factors in breast milk. The results show that cannabinoids are present in the milk of cannabis users, accompanied by increased lactose levels and decreased SIgA levels, which may have significant implications for infant health.
PEDIATRIC RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Natalie Dinavitser, Elkana Kohn, Maya Berlin, Nurit Brandriss, Adina Bar-Chaim, Rimona Keidar, Ayelet Livne, David Stepensky, Matitiahu Berkovitch, Revital Sheinberg
Summary: This study examined the excretion of levetiracetam in breastmilk in breastfeeding women with epilepsy, finding that exposure to the drug in breastmilk may lead to infant toxicities. The study also revealed a close correlation between levetiracetam dose, maternal serum concentration, and breastmilk levels. Further studies are needed to assess the short- and long-term safety of levetiracetam in breastfeeding infants.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Medicine, Research & Experimental
Parul Singh, Noora Al Mohannadi, Selvasankar Murugesan, Fajr Almarzooqi, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Annalisa Terranegra, Rose McGready, Francois Nosten, Damien Chaussabel, Souhaila Al Khodor
Summary: This study investigated the microbial communities in breast milk of mothers with preterm deliveries and found that the microbial communities became increasingly diverse and distinct as the breast milk matured. There were significant differences in the community structures between preterm and term breast milk samples. This study highlights the significant influence of pregnancy-related complications on the composition and diversity of breast milk microbiota, paving the way for improving maternal and infant health outcomes.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Review
Nutrition & Dietetics
Yuandi Xi, Xianyun Wang, Kuo Liu, Huanmei Zhang, Xiangnan Ren, Ai Zhao, Jianqiang Lai, Rong Xiao
Summary: This study systematically collected information on vitamin E concentration in healthy breast milk during different stages of lactation. The study found that the concentration of vitamin E in colostrum was lower in Asian countries compared to Western countries, while the concentration in mature milk was similar across regions.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Qiu-Ye Lan, Si-Yu Huang, Chen-Yu Jiang, Meng-Tao Yang, Tong Wu, Xiao-Yan Chen, Zhao-Yan Liu, Wei Wei, Xing-Guo Wang, Hui-Lian Zhu
Summary: This study analyzed the molecular species of TAG in human milk fat and its changes during lactation using UPLC-Q-TOF-MS. The results showed that the changes in TAG mainly occurred in the early stages of lactation, and the TAG profile became stable after 200 days of lactation. Odd chain fatty acids may be important markers for identifying different lactation stages.
Article
Food Science & Technology
Alexandra-Maria Basdeki, Dimitrios G. Fatouros, Costas G. Biliaderis, Thomas Moschakis
Summary: The study revealed that the microstructure and physicochemical properties of human milk are influenced by the stage of lactation. The unique composition and structure of human milk proteins may lead to its special functional characteristics, contributing to the development of innovative products.
CURRENT RESEARCH IN FOOD SCIENCE
(2021)
Article
Multidisciplinary Sciences
Anna Ziomkiewicz, Magdalena Babiszewska, Anna Apanasewicz, Magdalena Piosek, Patrycja Wychowaniec, Agnieszka Cierniak, Olga Barbarska, Marek Szoltysik, Dariusz Danel, Szymon Wichary
Summary: The study examined the impact of perinatal psychosocial stress on breast milk composition in a sample of 146 Polish breastfeeding mothers and their infants. Stress reactivity was found to be associated with milk fat and fatty acids, and negatively correlated with milk lactose. Maternal psychological status during the peripartum period should be monitored to promote breastfeeding and infant nutrition.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Naina Dwivedi, Abbas Ali Mahdi, Sujata Deo
Summary: The present study aimed to assess the safety of infants in North India in relation to the presence of persistent organochlorine pesticides (OCPs) in breast milk, which could transfer endocrine-disrupting chemicals to newborns. Samples of colostrum and breast milk were collected and analyzed for pesticide concentration. Results showed that OCPs concentration was higher in breast milk compared to colostrum, indicating an increase in pesticides contamination over lactation. The study also found that women consuming non-vegetarian food had higher exposure to OCPs, and factors such as mother's age, gestational age, and infant birth weight were associated with OCPs levels in colostrum and breast milk. The study highlights the need for regulation and further research on the relationship between pesticide residues in breast milk and maternal and child health.
ENVIRONMENTAL RESEARCH
(2023)
Review
Microbiology
Sophie I. S. Wedekind, Natalie S. Shenker
Summary: Humans have always coexisted with viruses, and evolutionary pressure has shaped the intrinsic properties of lactation and milk to support the neonate's immune system and protect against pathogens. Human milk contains specific components that support immune learning and maturation, as well as provide direct protection against microorganisms. However, there is a lack of awareness among the public and healthcare professionals about the specific antiviral properties of human milk beyond the production of maternal antibodies.
Article
Food Science & Technology
Miaomiao Zhou, Fei Huang, Xinyi Du, Changfa Wang, Guiqin Liu
Summary: This study examines the effects of different lactation stages on the composition and function of donkey milk microbiota. The results show that the microbial composition and functions of donkey milk are significantly influenced by lactation stages. Donkey milk contains beneficial bacteria but also poses potential health risks.
Article
Nutrition & Dietetics
Blanca Grases-Pinto, Mar Abril-Gil, Paulina Torres-Castro, Margarida Castel, Maria J. Rodriguez-Lagunas, Francisco J. Perez-Cano, Angels Franch
Summary: The study analyzed the content of immunoglobulins and key adipokines and growth factors in rat breast milk throughout the lactation period, comparing them with corresponding plasma levels. Changes were observed in the levels of certain factors, including an increase in TGF-beta 2 and -beta 3 in the first week, and a decrease in FGF21 in the second period. Positive correlations were found between milk and plasma levels of IgM, IgG, and adipokines.
Article
Biochemistry & Molecular Biology
Ce Qi, Jingbo Zhou, Huayu Tu, Rundan Tu, Hong Chang, Jie Chen, Duo Li, Jin Sun, Renqiang Yu
Summary: Key anaerobic gut-associated bacteria are transmitted from the mother to the infant's gut during lactation, particularly in the colostrum phase. Other bacteria, such as Streptococcus salivarius, Bifidobacterium longum, and Lactobacillus gasseri, can also be transferred between the maternal gut, breast milk, and newborn gut depending on specific amplicon sequence variants. This suggests that targeted isolation of key microorganisms from breast milk could be used to manipulate the microbiota of either breast milk or newborns for promoting neonatal health.
Article
Agriculture, Dairy & Animal Science
Lea A. Rempel, William T. Oliver, Jeremy R. Miles
Summary: Preweaning piglet growth is associated with milk quality and consumption, with specific milk traits linked to piglet growth.
JOURNAL OF ANIMAL SCIENCE
(2023)