4.6 Editorial Material

Targeting female hormone receptors as cervical cancer therapy

Journal

TRENDS IN ENDOCRINOLOGY AND METABOLISM
Volume 26, Issue 8, Pages 399-401

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tem.2015.06.004

Keywords

human papillomavirus; estrogen receptor alpha; progesterone receptor; cervical cancer; hormonal therapy

Funding

  1. NCI NIH HHS [CA188646, R01 CA188646] Funding Source: Medline

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While preventive methods for cervical cancer are effective, available therapies for advanced cervical cancers are ineffective. New experimental evidence points to weaknesses of prior studies and provides fresh molecular insights on the opposing roles of estrogen receptor alpha (ER alpha) and the progesterone receptor (PR) that may be translated into valuable treatments for a subset of cervical cancers.

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