Successful use of ofatumumab in two cases of early-onset juvenile SLE with thrombocytopenia caused by a mutation in protein kinase C δ

Short-term efficacy and safety of rituximab therapy in refractory systemic lupus erythematosus: results from the British Isles Lupus Assessment Group Biologics Register

(2017) Eoghan M McCarthy et al.   RHEUMATOLOGY

Clinical impact of a targeted next-generation sequencing gene panel for autoinflammation and vasculitis

(2017) Ebun Omoyinmi et al.   PLoS One

Ofatumumab in two pediatric nephrotic syndrome patients allergic to rituximab

(2016) Marina Vivarelli et al.   PEDIATRIC NEPHROLOGY

Early-Onset Juvenile SLE Associated With a Novel Mutation in Protein Kinase C δ

(2016) Sira Nanthapisal et al.   PEDIATRICS

Successful treatment of life-threatening autoimmune haemolytic anaemia with ofatumumab in a patient with systemic lupus erythematosus

(2016) Theofanis Karageorgas et al.   RHEUMATOLOGY

Potentially Beneficial Effect of Hydroxychloroquine in a Patient with a Novel Mutation in Protein Kinase Cδ Deficiency

(2015) Ayca Kiykim et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Safety and efficacy of ofatumumab in relapsing-remitting multiple sclerosis: A phase 2 study

(2014) P. S. Sorensen et al.   NEUROLOGY

Ofatumumab: a novel treatment for severe systemic lupus erythematosus

(2014) C. C. Thornton et al.   RHEUMATOLOGY

Protein Kinase Cδ Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell-Defective Apoptosis and Hyperproliferation

(2013) Alexandre Belot et al.   ARTHRITIS AND RHEUMATISM

B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C  

(2013) E. Salzer et al.   BLOOD

Loss-of-function of the protein kinase C   (PKC ) causes a B-cell lymphoproliferative syndrome in humans

(2013) H. S. Kuehn et al.   BLOOD

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: data from the European Group for Blood and Marrow Transplantation registry

(2012) B Alchi et al.   LUPUS

Monogenic forms of systemic lupus erythematosus: new insights into SLE pathogenesis

(2012) Alexandre Belot et al.   Pediatric Rheumatology

Ofatumumab, a fully human anti-CD20 monoclonal antibody, in biological-naive, rheumatoid arthritis patients with an inadequate response to methotrexate: a randomised, double-blind, placebo-controlled clinical trial

(2011) P. C. Taylor et al.   ANNALS OF THE RHEUMATIC DISEASES

Ofatumumab

(2010) Michael J. Keating et al.   NATURE REVIEWS DRUG DISCOVERY

First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: results of a phase 1/2 trial

(2008) A. Hagenbeek et al.   BLOOD

Phosphorylation of Protein Kinase Cδ on Distinct Tyrosine Residues Induces Sustained Activation of Erk1/2 via Down-regulation of MKP-1

(2008) Stephanie L. Lomonaco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY