Identification of GATA6 Sequence Variants in Patients With Congenital Heart Defects

A gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects

(2009) M. G. Posch et al.   JOURNAL OF MEDICAL GENETICS

GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling

(2009) K. Kodo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Gain-of-Function TBX5 Mutation Is Associated With Atypical Holt–Oram Syndrome and Paroxysmal Atrial Fibrillation

(2008) Alex V. Postma et al.   CIRCULATION RESEARCH

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

(2008) Roong Zhao et al.   DEVELOPMENTAL BIOLOGY

Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development

(2008) Meenakshi Maitra et al.   DEVELOPMENTAL BIOLOGY

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling

(2008) K. L. McBride et al.   HUMAN MOLECULAR GENETICS

The developmental genetics of congenital heart disease

(2008) Benoit G. Bruneau   NATURE