Journal
PEDIATRIC RADIOLOGY
Volume 43, Issue 7, Pages 882-885Publisher
SPRINGER
DOI: 10.1007/s00247-012-2579-8
Keywords
Molybdenum cofactor deficiency; Diffusion-weighted imaging; Cystic encephalomalacia; Ulegyria
Ask authors/readers for more resources
We present a neonate with molybdenum cofactor deficiency imaged at presentation during the first month of life and at 5 months with diffusion-weighted brain MRI. While the imaging features of this disease have previously been reported, this case highlights a distinctive initial pattern of widespread restricted diffusion involving cortex at the depths of sulci. Other case series have published diffusion-weighted images (DWI) with this pattern but never specifically commented on this finding. This distinct DWI pattern also accounts for the configuration of ulegyria frequently described on later imaging. Early recognition of this unique initial DWI pattern could avoid misdiagnosis and better direct counseling and management.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available