Article
Psychiatry
Neera Ghaziuddin, Tareq Yaqub, Wael Shamseddeen, Priyanka Reddy, Hannah Reynard, Daniel Maixner
Summary: The study aimed to investigate the naturalistic clinical course in adolescent and young adult patients with developmental delays and catatonia, when maintenance electroconvulsive therapy (M-ECT) frequency was reduced due to COVID-19 restrictions. Participants showed significant decline in symptoms, particularly motor symptoms, leading to rehospitalization for some patients.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Toshinori Nakamura, Misaki Shimizu-Ichikawa, Kazuhito Takahashi, Sari Shimizu, Takashi Ichiyama, Keisuke Todoroki, Masataka Konno, Daisuke Amada, Daimei Sasayama, Shinsuke Washizuka
Summary: This article describes a case of sudden respiratory failure during the treatment of catatonia, which required intensive care. Electroconvulsive therapy (ECT) was successfully administered in the intensive care unit, relieving the catatonia symptoms and improving the respiratory failure. It highlights the importance of monitoring the patient's physical and psychological symptoms, as respiratory status may deteriorate rapidly in a catatonic state.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Psychiatry
Lauren Katzell, Emily Beydler, Amilcar Silva dos Santos, Richa Vijayvargiya, Brent R. Carr
Summary: This article presents the clinical features and treatment methods of neuroleptic malignant syndrome (NMS), emphasizing the effectiveness of electroconvulsive therapy (ECT) in acute treatment. A 52-year-old female patient with NMS-like symptoms induced by discontinuation of medication received urgent ECT and achieved rapid improvement. The study suggests that ECT has potential efficacy in reducing mortality associated with NMS and malignant catatonia.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Aditi Sharma, Vinod Sharma
Summary: This is a case of cannabis-induced catatonia in an 18-year-old Hispanic male with no prior psychiatric history. Electroconvulsive therapy (ECT) proved to be a useful treatment choice, resulting in significant improvement in symptoms. This example emphasizes the potential dangers of cannabis usage, particularly in susceptible individuals, and underscores the importance of recognizing and treating catatonia as a possible side effect of cannabis use.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Clinical Neurology
Phern Chern Tor, Xiao Wei Tan, Donel Martin, Colleen Loo
Summary: Electroconvulsive Therapy (ECT) varies in use and effectiveness for different indications worldwide, but can significantly improve clinical global impression, quality of life, and global functioning for patients with acute psychosis, mania, depression, psychotic depression, and catatonia.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2021)
Article
Clinical Neurology
Adrienne Clermont, Daphne Loubriel, Erin Li, Darlene Mitera, Susan Samuels
Summary: This case highlights the importance of prompt diagnosis and treatment of catatonia in adolescent patients, as well as the safety and efficacy of ECT in this population.
Article
Behavioral Sciences
Rikinkumar S. Patel, Kelsey Hobart, Abhishek Wadhawan, Ankit Chalia, Nagy A. Youssef
Summary: This study aimed to determine the rates of electroconvulsive therapy (ECT) use and its impact on inpatient length of stay and cost in adolescents with catatonia and schizophrenia spectrum disorders. The results showed that the overall utilization rate of ECT was 12.9% in this population. The utilization rate varied by patient demographics and hospital characteristics, with higher rates observed in Whites, private health insurance beneficiaries, and certain regions. Public, teaching, and large bed-size hospitals were more likely to administer ECT to adolescent inpatients with catatonia.
Review
Critical Care Medicine
Jennifer Connell, Mark Oldham, Pratik Pandharipande, Robert S. Dittus, Amanda Wilson, Matthew Mart, Stephan Heckers, E. Wes Ely, Jo Ellen Wilson
Summary: Catatonia is a clinical syndrome characterized by a variety of psychomotor, neurological, and behavioral changes. It can range from decreased movement to extreme agitation. It can occur as a primary psychiatric condition or secondary to a general medical illness, and may co-occur with delirium or coma. Malignant catatonia is a life-threatening form of acute brain dysfunction that manifests with autonomic abnormalities and can be caused by a primary psychiatric condition or a medical cause. Prompt recognition and treatment are crucial because malignant catatonia can be fatal without intervention.
JOURNAL OF INTENSIVE CARE MEDICINE
(2023)
Article
Clinical Neurology
Maria Lidia Gerra, Carlotta Mutti, Lorenzo Luvie, Benyamin Daniel Daniel, Irene Florindo, Edoardo Picetti, Liborio Parrino, Carlo Marchesi, Lucia Zinno
Summary: This study describes a challenging case of a young woman with relapsing-remitting malignant catatonia and emphasizes the importance of interdisciplinary communication between neurologists and psychiatrists.
Article
Neuroimaging
Qiang Wei, Yang Ji, Tongjian Bai, Meidan Zu, Yuanyuan Guo, Yuting Mo, Gongjun Ji, Kai Wang, Yanghua Tian
Summary: Recent studies have found that ECT reorganizes dysregulated cerebral networks, including the affective network, CCN, and DMN, and little is known about the relationship between cerebro-cerebellar connectivity alterations following ECT and antidepressant effects or cognitive impairment. The study identified enhanced cerebro-cerebellar functional connectivity from left lobule VI to left sgACC, which may ameliorate cognitive impairment induced by ECT. The findings suggest a potential neural pathway for mitigating cognitive impairment following ECT.
BRAIN IMAGING AND BEHAVIOR
(2021)
Article
Clinical Neurology
Margot J. Wagenmakers, Mardien L. Oudega, Federica Klaus, David Wing, Gwendolyn Orav, Laura K. M. Han, Julia Binnewies, Aartjan T. F. Beekman, Dick J. Veltman, Didi Rhebergen, Eric van Exel, Lisa T. Eyler, Annemieke Dols
Summary: This study investigated the BrainAge gap in patients with late-life depression (LLD) and its associations with clinical characteristics. The results showed that LLD patients had an older BrainAge than their chronological age, with a gap of 1.8 years. However, there was high variability and no significant associations with clinical measures were found. Larger samples are needed for further research on brain aging and the usability of BrainAge gap as a potential biomarker in LLD.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Ken Wada, Akiko Kurata, Takashi Iwamoto, Junji Gon, Hiroma Shimizu
Summary: The study reviewed medical records of patients undergoing ECT and found that oral theophylline augmentation technique was effective in achieving better outcomes, with the majority of patients completing the treatment course successfully.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Pharmacology & Pharmacy
Sigrid Breit, Agnes Meyer, Wolfgang Schmitt, Tobias Bracht, Sebastian Walther
Summary: ECT has been proven to be highly effective in the treatment of catatonia, achieving response rates of about 80 to 100%. This retrospective study analyzed data from 20 patients with catatonia who underwent ECT from 2008 to 2021. The results showed excellent response to ECT, particularly for motor inhibition symptoms such as stupor and mutism. The presence of grasp reflex was identified as a predictor of late response.
PHARMACOPSYCHIATRY
(2023)
Review
Psychiatry
Tuna Hasoglu, Andrew Francis, Charles Mormando
Summary: This article provides a review of ECT-resistant catatonia and presents a new treatment approach. The study found that in some patients, lorazepam and ECT were not effective in fully alleviating catatonic symptoms, but symptoms improved after memantine treatment.
JOURNAL OF THE ACADEMY OF CONSULTATION-LIAISON PSYCHIATRY
(2022)
Article
Psychiatry
Maximilian Cronemeyer, Carlos Schoenfeldt-Lecuona, Maximilian Gahr, Ferdinand Keller, Alexander Sartorius
Summary: This study compared the effectiveness of different MC treatment approaches and found that combining benzodiazepines and electroconvulsive therapy (ECT) had the most favorable outcomes, with early initiation of benzodiazepines being associated with favorable outcomes. Patients with severe MC were more likely to receive intensive care treatment and had a higher risk of death compared to those with moderate MC.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2022)
Article
Clinical Neurology
Ani Gok, Seha Kamil Saygili, Sebuh Kurugoglu, Sema Saltik, Nur Canpolat
Summary: This study examines the occurrence of nephrolithiasis in children with type 1 SMA and identifies hypercalciuria and high urine specific gravity as common risk factors. The study suggests that children with SMA type 1 may have an increased risk of nephrolithiasis compared to the general population.
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Glenn S. Rivera, Jesse A. Stokum, Janet Dean, Cristina L. Sadowsky, Allan J. Belzberg, Matthew J. Elrick
Summary: This study evaluated the surgical efficacy of nerve transfer surgery in patients with acute flaccid myelitis (AFM) and found that preoperative clinical and neurophysiological data play a valuable role in preoperative planning and patient selection. The postoperative outcomes demonstrated that nerve transfer surgery is an effective strategy to restore strength.
PEDIATRIC NEUROLOGY
(2024)
Review
Clinical Neurology
Tristan T. Sands, Jennifer N. Gelinas
Summary: This review explores the concept of epileptic encephalopathy (EE) in pediatric epilepsy, discussing the potential impact of epileptic activity on normal brain development and mechanisms underlying cognitive and behavioral impairments. The findings highlight the threat of epileptic activity to normal brain physiology and development.
PEDIATRIC NEUROLOGY
(2024)
Editorial Material
Clinical Neurology
Grace Gombolay, Melissa A. Walker
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Salman Rashid, Monisha Goyal, Kathryn Lalor, Khaled Al-Robaidi, Vivek Shukla, Fazlur Rahman, Manimaran Ramani
Summary: This study investigated the seizure risk in asymptomatic preterm infants with high-grade intraventricular hemorrhage who underwent long-term video electroencephalographic monitoring. The findings showed that approximately 16% of these infants had seizures, and those with seizures were younger and more likely to be remonitored.
PEDIATRIC NEUROLOGY
(2024)
Letter
Clinical Neurology
Bernadeta Zabielska, Natalia Rzewuska, Sergiusz Jozwiak
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Kelly C. Burk, Maki Kaneko, Catherine Quindipan, My H. Vu, Maritza Feliz Cepin, Jonathan D. Santoro, Michele Van Hirtum-Das, Deborah Holder, Gordana Raca
Summary: This study compared the diagnostic yields of chromosomal microarray (CMA) and epilepsy-genes sequencing (EGS) for genetic epilepsy etiologies. It found that EGS had a significantly higher diagnostic yield than CMA, especially for patients with infantile seizure onset and additional neurological findings.
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Ursula Thome, Larissa A. Batista, Renata P. Rocha, Vera C. Terra, Ana Paula A. Hamad, Americo C. Sakamoto, Antonio C. Santos, Marcelo Santos, Helio R. Machado
Summary: Rasmussen encephalitis (RE) is a characterized by pharmacoresistant epilepsy and progressive neurological deficits. Surgical disconnection of the affected hemisphere is considered the treatment of choice, although the precise etiology is still unknown. This study reports the clinical, electrographic, and neuroimaging features of children and adolescents who underwent hemispheric surgery (HS) for the treatment of RE.
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Michal Tzadok, Rotem Gur-Pollack, Hadar Florh, Yael Michaeli, Tal Gilboa, Mirit Lezinger, Eli Heyman, Veronika Chernuha, Irina Gudis, Andreea Nissenkorn, Tally Lerman-Sagie, Bruria Ben Zeev, Shimrit Uliel-Sibony
Summary: Purified CBD is well-tolerated and effective in reducing seizure frequency in children and young adults with drug-resistant epilepsy.
PEDIATRIC NEUROLOGY
(2024)
Editorial Material
Clinical Neurology
Zimeng Ye, Sufang Lin, Xia Zhao, Mathew Wallis, Xinyi Gao, Li Sun, Jiarui Wu, Jing Duan, Yi Yao, Lin Li, Li Chen, Dezhi Cao, Zhanqi Hu, Victor W. Zhang, Samuel F. Berkovic, Ingrid E. Scheffer, Jianxiang Liao, Michael S. Hildebrand
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Nicolas J. Abreu, Madeline Chiujdea, Shanshan Liu, Bo Zhang, Sarah J. Spence
Summary: This study found a low completion rate of chromosomal microarray (CMA) testing for patients with autism spectrum disorder (ASD). Provider recommendation and more follow-up visits were associated with CMA completion. Age, intellectual disability or global developmental delay, first-degree relative with ASD, and public insurance were all related to CMA completion. Parental concern and cost/insurance coverage were the most frequently documented barriers.
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Wafa Bouchaala, Sirine Laroussi, Yosra Mzid, Imen Maaloul, Olfa Jallouli, Salma Zouari, Sihem Ben Nsir, Zeineb Mnif, Fatma Kammoun, Chahnez Triki
Summary: Moyamoya angiopathy is a rare but serious cerebrovascular disease in children, which may result in arterial ischemic stroke. The clinical and radiological presentations can vary and are often overlooked. Early diagnosis and treatment are crucial.
PEDIATRIC NEUROLOGY
(2024)
Letter
Clinical Neurology
Eline M. C. Hamilton, Pinar Topaloglu, Jigyasha Sinha, Francesco Nicita, Genevieve Bernard, S. Ali Fatemi, Marjo S. van der Knaap
PEDIATRIC NEUROLOGY
(2024)
Article
Clinical Neurology
Muhamad Azamin Anuar, Muhammad'Adil Zainal Abidin, Soo Hong Tan, Cai Fong Yeap, Nor Azni Yahaya
Summary: This study conducted in Malaysia found that most infants with epilepsy can achieve seizure remission. However, poor seizure control and developmental delay are associated with abnormal EEG background and neuroimaging abnormalities.
PEDIATRIC NEUROLOGY
(2024)