The EYA-SO/SIX complex in development and disease

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear

(2012) M. Ahmed et al.   DEVELOPMENT

Eya1-Six1 Interaction Is Sufficient to Induce Hair Cell Fate in the Cochlea by Activating Atoh1 Expression in Cooperation with Sox2

(2012) Mohi Ahmed et al.   DEVELOPMENTAL CELL

SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer

(2012) Chu-An Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome

(2011) Q.-f. Wang et al.   BLOOD

String (Cdc25) regulates stem cell maintenance, proliferation and aging in Drosophila testis

(2011) M. Inaba et al.   DEVELOPMENT

Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis

(2011) Xuguang Nie et al.   DEVELOPMENTAL BIOLOGY

SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation

(2010) X. Nie et al.   DEVELOPMENT

Autoregulatory binding sites in the zebrafish six3a promoter region define a new recognition sequence for Six3 proteins

(2010) Clotilde S. Suh et al.   FEBS Journal

Sipl1 and Rbck1 Are Novel Eya1-Binding Proteins with a Role in Craniofacial Development

(2010) K. Landgraf et al.   MOLECULAR AND CELLULAR BIOLOGY

The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration and invasion of tumor cells

(2010) R N Pandey et al.   ONCOGENE

EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis

(2009) Youe Li et al.   BIOLOGY OF THE CELL

Advances in early kidney specification, development and patterning

(2009) G. R. Dressler   DEVELOPMENT

Ret-Dependent Cell Rearrangements in the Wolffian Duct Epithelium Initiate Ureteric Bud Morphogenesis

(2009) Xuan Chi et al.   DEVELOPMENTAL CELL

Interactions with the Abelson Tyrosine Kinase Reveal Compartmentalization of Eyes Absent Function between Nucleus and Cytoplasm

(2009) Wenjun Xiong et al.   DEVELOPMENTAL CELL

EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts withSIX3both physically and functionally

(2009) Yuichi Abe et al.   HUMAN MUTATION

Dephosphorylation of the C-terminal Tyrosyl Residue of the DNA Damage-related Histone H2A.X Is Mediated by the Protein Phosphatase Eyes Absent

(2009) Navasona Krishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

(2009) Peter J. Cook et al.   NATURE

Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

(2009) S J Miller et al.   ONCOGENE

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

(2008) Akio Kobayashi et al.   Cell Stem Cell

Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney

(2008) Joshua W. Mugford et al.   DEVELOPMENTAL BIOLOGY

Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4

(2008) Binglai Chen et al.   DEVELOPMENTAL BIOLOGY

SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development

(2008) S. Weber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY