Clinical and Molecular Insights into Tuberous Sclerosis Complex Renal Disease

Developments in the management of autosomal dominant polycystic kidney disease

(2016) Robert Schrier   Therapeutics and Clinical Risk Management

Rapamycin Ameliorates PKD Resulting from Conditional Inactivation of Pkd1

(2010) J. M. Shillingford et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Glomerulocystic kidney disease

(2010) John J. Bissler et al.   PEDIATRIC NEPHROLOGY

Ciliary biology: Understanding the cellular and genetic basis of human ciliopathies

(2009) Magdalena Cardenas-Rodriguez et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Renal Angiomyolipoma

(2009) Hakan Aydin et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

(2009) Cleo S. Bonnet et al.   HUMAN MOLECULAR GENETICS

Polycystin-1 Regulates Extracellular Signal-Regulated Kinase-Dependent Phosphorylation of Tuberin To Control Cell Size through mTOR and Its Downstream Effectors S6K and 4EBP1

(2009) G. Distefano et al.   MOLECULAR AND CELLULAR BIOLOGY

FGF signalling during embryo development regulates cilia length in diverse epithelia

(2009) Judith M. Neugebauer et al.   NATURE

Renal involvement in tuberous sclerosis complex and von Hippel–Lindau disease: shared disease mechanisms?

(2009) Brian J Siroky et al.   Nature Reviews Nephrology

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia

(2008) Vishal Patel et al.   HUMAN MOLECULAR GENETICS

Clinical Correlates of Renal Angiomyolipoma Subtypes in 209 Patients: Classic, Fat Poor, Tuberous Sclerosis Associated and Epithelioid

(2008) Brian R. Lane et al.   JOURNAL OF UROLOGY

Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis

(2008) Umut Ozcan et al.   MOLECULAR CELL

Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis

(2008) John J. Bissler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2−/− Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM

(2008) Elena Lesma et al.   PLoS One

Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis

(2007) Tomohiro Nakamura et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY