Article
Nutrition & Dietetics
Mario Flores-Aldana, Marta Rivera-Pasquel, Armando Garcia-Guerra, Jesus Giovanni Perez-Cortes, Juan E. Barcena-Echegollen
Summary: This study aimed to assess the effect of vitamin D supplementation at different doses on serum 25(OH)D concentrations in preschool children. After three months, there was a significant increase in serum concentrations of 25(OH)D and a decrease in the prevalence of vitamin D deficiency. No adverse effects were observed.
Review
Environmental Sciences
Jutti Levita, Gofarana Wilar, Ika Wahyuni, Lidya Cahyo Bawono, Tiara Ramadaini, Rohani Rohani, Ajeng Diantini
Summary: Intoxication of vitamin D is not commonly seen in pediatrics. This review provides insights into the clinical toxicology of vitamin D in pediatrics, including the mechanism, case reports, and management of vitamin D poisoning.
Review
Nutrition & Dietetics
Rakesh Balachandar, Raghu Pullakhandam, Bharati Kulkarni, Harshpal Singh Sachdev
Summary: This study found that cholecalciferol was more effective than ergocalciferol in improving vitamin D status and regulating PTH levels, regardless of participant demographics, dosage, and vehicle of supplementation.
Review
Medicine, General & Internal
Riccardo Nocini, Brandon M. M. Henry, Camilla Mattiuzzi, Giuseppe Lippi
Summary: This review examined the relationship between vitamin D and tinnitus, and found a link between lower serum vitamin D levels and tinnitus. Further research is needed to explore whether vitamin D supplementation can help prevent and/or improve tinnitus.
Review
Nutrition & Dietetics
Eva Pal, Zoltan Ungvari, Zoltan Benyo, Szabolcs Varbiro
Summary: Deficiency in vitamin D affects a significant portion of the Western population and plays a crucial role in cardiovascular health. This deficiency leads to adverse vascular remodeling, endothelial dysfunction, vascular inflammation, and increased risk for cardiovascular and cerebrovascular diseases. Understanding the complex role of vitamin D deficiency is important for intervention and prevention among cardiologists, dietitians, and geriatricians.
Review
Health Care Sciences & Services
Michael Wakeman
Summary: The potential effects of medications on vitamin D status are varied and may require more research to better understand the interactions between vitamin D and drugs. Healthcare providers should be aware of the potential for vitamin D depletions induced by medications, especially in elderly patients on multiple-drug therapy, and consider supplementation if necessary.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2021)
Article
Cardiac & Cardiovascular Systems
Debasish Banerjee, Nihil Chitalia, Irina Chis Ster, Evan Appelbaum, Ravi Thadhani, Juan Carlos Kaski, David Goldsmith
Summary: A study on vitamin D supplementation in stable, non-diabetic CKD patients showed no beneficial effects on left ventricular mass.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2021)
Article
Endocrinology & Metabolism
Stefano Ciardullo, Emanuele Muraca, Rosa Cannistraci, Silvia Perra, Guido Lattuada, Gianluca Perseghin
Summary: This study analyzes data from a national survey and finds an association between 25(OH)D levels and NAFLD and liver fibrosis, suggesting a potential role of vitamin D in the occurrence and progression of NAFLD.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Article
Spectroscopy
Ojars Balcers, Ulises Miranda, Rita Veilande
Summary: The study aims to explore the feasibility of developing non-invasive optical sensors for Vitamin D2 and D3 by calculating their optical properties and comparing them with traditional mass spectroscopy and immunoassay methods. The findings are significant for the convenience and accuracy of measuring the concentrations of these substances in medical applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Endocrinology & Metabolism
Marco Zaffanello, Angelo Pietrobelli, Luana Nosetti, Giorgio Piacentini, Giuliana Ferrante, Michele Piazza, Alessandra Guzzo, Franco Antoniazzi
Summary: The study found a correlation between the search volume of vitamin D and its adverse biological effects (hypercalcemia, renal failure, kidney stones, bone density). Interest in kidney stones increased more rapidly than other search terms. The highest concentration of interest in vitamin D was in North America, Europe, India, and Australia, while interest in ergocalciferol was higher in Central and South America, Spain, and Thailand.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Review
Food Science & Technology
Joel B. Johnson, C. P. Ekanayake, Federico Caravani, Janice S. Mani, Pawan Lal, Sarah J. Calgaro, Shirtika S. Prasad, Robyn D. Warner, Mani Naiker
Summary: Vitamin D plays crucial roles in various bodily functions, and meat products appear to be a significant source of vitamin D for much of the global population.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Agriculture, Dairy & Animal Science
Miranda C. M. Dosi, Chris M. Riggs, Jessica May, Adele Lee, Eugenio Cillan-Garcia, Joe Pagan, Bruce C. McGorum
Summary: Hong Kong racehorses have low serum vitamin D-2 and total vitamin D concentrations and rely on D-3 supplementation to maintain adequate vitamin D status.
Article
Nutrition & Dietetics
Bridget A. Baxter, Michaela G. Ryan, Stephanie M. LaVergne, Sophia Stromberg, Kailey Berry, Madison Tipton, Nicole Natter, Nikiah Nudell, Kim McFann, Julie Dunn, Tracy L. Webb, Michael Armstrong, Nichole Reisdorph, Elizabeth P. Ryan
Summary: This study investigates the association between vitamin D deficiency and COVID-19 severity among survivors. The findings show a correlation between vitamin D deficiency and severe cases, as well as the presence of post-acute sequelae of COVID-19 (PASC) among survivors. Gender and BMI are also found to be related to vitamin D levels, but not to the presence of PASC.
Article
Transplantation
Arpana Iyengar, Nivedita Kamath, Hamsa Reddy, Jyoti Sharma, Jyoti Singhal, Susan Uthup, Sudha Ekambaram, Sumithra Selvam, Anja Rahn, Dagmar-C Fischer, Mandy Wan, Rukshana Shroff
Summary: In children with chronic kidney disease, different dosing regimens of oral cholecalciferol achieved similar 25OHD concentrations without toxicity. Children with glomerular disease required higher doses of cholecalciferol compared to those with non-glomerular disease.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Pediatrics
Nivedita Kamath, Arpana Iyengar, Hamsa Reddy, Jyoti Sharma, Jyoti Singhal, Sudha Ekambaram, Susan Uthup, Sumithra Selvam, Mandy Wan, Anja Rahn, Dagmar Christiane-Fischer, Rukshana Shroff
Summary: This study analyzed the effects of different dosing regimens of cholecalciferol supplementation on bone biomarkers. The results showed that cholecalciferol supplementation significantly increased bone formation, and the three dosing regimens had similar effects on bone biomarkers.
PEDIATRIC NEPHROLOGY
(2023)
Article
Pharmacology & Pharmacy
Mandy Wan, Bruce Green, Arpana Aprameya Iyengar, Nivedita Kamath, Hamsa V. Reddy, Jyoti Sharma, Jyoti Singhal, Susan Uthup, Sudha Ekambaram, Sumithra Selvam, Greta Rait, Rukshana Shroff, Jignesh P. Patel
Summary: This study developed a population PK model of colecalciferol in children with CKD, finding wide variability in PK related to total body weight and suggesting a weight-based dosing strategy to optimize current dosing recommendations.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Review
Pediatrics
Vanessa Shaw, Caroline Anderson, An Desloovere, Larry A. Greenbaum, Dieter Haffner, Christina L. Nelms, Fabio Paglialonga, Nonnie Polderman, Leila Qizalbash, Jose Renken-Terhaerdt, Stella Stabouli, Jetta Tuokkola, Johan Vande Walle, Bradley A. Warady, Rukshana Shroff
Summary: Proper nutritional management is crucial for children with chronic kidney disease (CKD) to maintain normal growth and development. Infants with CKD have specific nutritional needs, and inadequate nutrition can lead to growth impairment and abnormal neurodevelopment.
PEDIATRIC NEPHROLOGY
(2023)
Letter
Urology & Nephrology
Rizky I. Sugianto, Nima Memaran, Bernhard M. W. Schmidt, Anke Doyon, Daniela Thurn-Valsassina, Harika Alpay, Ali Anarat, Klaus Arbeiter, Karolis Azukaitis, Aysun K. Bayazit, Ipek K. Bulut, Salim Caliskan, Nur Canpolat, Ali Duzova, Jutta Gellerman, Jerome Harambat, Denise Homeyer, Mieczyslaw Litwin, Francesca Mencarelli, Lukasz Obrycki, Dusan Paripovic, Bruno Ranchin, Rukshana Shroff, Uwe Tegtbur, Jeannine von der Born, Ebru Yilmaz, Uwe Querfeld, Elke Wuehl, Franz Schaefer, Anette Melk
KIDNEY INTERNATIONAL
(2022)
Article
Transplantation
Mehmet S. Sever, Raymond Vanholder, Valerie Luyckx, Kai-Uwe Eckardt, Mykola Kolesnyk, Andrzej Wiecek, Ewa Pawlowicz-Szlarska, Daniel Gallego, Rukshana Shroff, Andrej Skoberne, Ionut Nistor, Mohamed Sekkarie, Dmytro Ivanov, Edita Noruisiene, Serhan Tuglular
Summary: During conflicts, people with kidney disease may face additional threats due to medical and logistical challenges. Acute kidney injury and treatment interruptions can worsen kidney function, and limitations in dialysis and availability of immunosuppressive medications increase the risk of complications. Local preparedness, adjustments in treatment, telemedicine support, and referrals to higher-level hospitals are important measures to address these challenges.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Pediatrics
Nivedita Kamath, Arpana Iyengar, Hamsa Reddy, Jyoti Sharma, Jyoti Singhal, Sudha Ekambaram, Susan Uthup, Sumithra Selvam, Mandy Wan, Anja Rahn, Dagmar Christiane-Fischer, Rukshana Shroff
Summary: This study analyzed the effects of different dosing regimens of cholecalciferol supplementation on bone biomarkers. The results showed that cholecalciferol supplementation significantly increased bone formation, and the three dosing regimens had similar effects on bone biomarkers.
PEDIATRIC NEPHROLOGY
(2023)
Review
Pediatrics
Lale Sever, Gulseren Pehlivan, Nur Canpolat, Seha Saygili, Ayse Agbas, Ebru Demirgan, Jun Oh, Elena Levtchenko, Dymtro D. Ivanov, Rukshana Shroff
Summary: Pediatric patients on kidney replacement therapy are highly vulnerable during disasters due to limitations in dialysis treatments and shortage of medical resources. Proper measures and support are crucial to mitigate risks and provide necessary care.
PEDIATRIC NEPHROLOGY
(2023)
Article
Pediatrics
Yesim Ozdemir Atikel, Claus Peter Schmitt, Eszter Levai, Shazia Adalat, Rukshana Shroff, Nadine Goodman, Ismail Dursun, Ayse Seda Pinarbasi, Burcu Yazicioglu, Fabio Paglialonga, Karel Vondrak, Isabella Guzzo, Nikoleta Printza, Aleksandra Zurowska, Ilona Zagozdzon, Aysun Karabay Bayazit, Bahriye Atmis, Marcin Tkaczyk, Maria do Sameiro Faria, Ariane Zaloszyc, Augustina Jankauskiene, Mesiha Ekim, Alberto Edefonti, Sevcan A. Bakkaloglu
Summary: This study analyzed the impact of hospital and dialysis unit characteristics on hospitalizations for access-related complications in pediatric dialysis patients. The results showed that children's hospitals and pediatric-specific dialysis units were associated with a higher prevalence of automated peritoneal dialysis and hemodiafiltration use, and lower hospitalization rates.
PEDIATRIC NEPHROLOGY
(2023)
Review
Pediatrics
Mandy Wan, Lillian King, Natasha Baugh, Zainab Arslan, Evelien Snauwaert, Fabio Paglialonga, Rukshana Shroff
Summary: Functional constipation is a common problem in healthy children, and it poses even more risks for children with chronic kidney disease (CKD) and on dialysis. Constipation can have negative effects on catheter function and ultrafiltration in children on peritoneal dialysis. There may be a bidirectional relationship between constipation and CKD, with gut dysbiosis potentially playing a role. However, there is limited data on the safety and effectiveness of constipation treatments in patients with CKD.
PEDIATRIC NEPHROLOGY
(2023)
Review
Pediatrics
Evelien Snauwaert, Fabio Paglialonga, Johan Vande Walle, Mandy Wan, An Desloovere, Nonnie Polderman, Jose Renken-Terhaerdt, Vanessa Shaw, Rukshana Shroff
Summary: Dietary fiber is an essential part of a healthy child's diet, and children with adequate fiber intake have higher diet quality and nutrient density. However, many children, especially those with kidney diseases, do not meet the recommended fiber intake. Recent studies suggest that dietary fiber is important for children with kidney diseases, as it provides various health benefits and does not increase the risk of hyperkalemia or nutritional deficits. New studies and guidelines are needed to address dietary fiber intake in these children.
PEDIATRIC NEPHROLOGY
(2023)
Article
Pediatrics
Justine Bacchetta, Claus Peter Schmitt, Sevcan A. Bakkaloglu, Shelley Cleghorn, Maren Leifheit-Nestler, Agnieszka Prytula, Bruno Ranchin, Anne Schoen, Stella Stabouli, Johan van de Walle, Enrico Vidal, Dieter Haffner, Rukshana Shroff
Summary: Infants with CKD are highly susceptible to mineral and bone disorders, and this position paper provides guidelines for diagnosing and managing CKD-MBD in infants. The paper includes 34 clinical practice points, such as dietary control of calcium and phosphate, and medication recommendations. The strength of the statements in the paper may vary and should be tailored to individual patient needs by the treating physician.
PEDIATRIC NEPHROLOGY
(2023)
Article
Pediatrics
Molly R. Wong Vega, Dana Cerminara, An Desloovere, Fabio Paglialonga, Jose Renken-Terhaerdt, Johan Vande Walle, Vanessa Shaw, Stella Stabouli, Caroline Elizabeth Anderson, Dieter Haffner, Christina L. Nelms, Nonnie Polderman, Leila Qizalbash, Jetta Tuokkola, Bradley A. Warady, Rukshana Shroff, Larry A. Greenbaum
Summary: The nutritional management of children with AKI is complex due to the dynamic nature of the condition. The PRNT has developed CPRs to guide dietitians in providing optimal nutrition support in line with AKI medical treatments. Collaboration between dietitians and physicians is crucial in addressing challenges in nutrition assessment and adapting recommendations to individual patient needs.
PEDIATRIC NEPHROLOGY
(2023)
Article
Transplantation
Pieter Evenepoel, Hanne Skou Jorgensen, Jordi Bover, Andrew Davenport, Justine Bacchetta, Mathias Haarhaus, Ditte Hansen, Carolina Gracia-Iguacel, Markus Ketteler, Louise McAlister, Emily White, Sandro Mazzaferro, Marc Vervloet, Rukshana Shroff, European Renal Osteodystrophy EUROD, European Renal Assoc ERA, European Soc Pediat Nephrology ESPN
Summary: Mineral and bone disorders are commonly seen in patients with chronic kidney disease, which can lead to adverse health outcomes. The management of calcium intake is crucial for maintaining a neutral calcium balance and preventing bone diseases and fractures. However, current clinical practice guidelines lack specific recommendations on calcium intake. Therefore, experts in the field have provided key practice points to assist healthcare professionals, but these recommendations should be individualized based on patient needs.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Editorial Material
Transplantation
Rukshana Shroff, Carlo Basile, Frank van der Sande, Sandip Mitra
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Pediatrics
Priyanka Khandelwal, Sarit Shah, Louise Mcalister, Shelley Cleghorn, Lillian King, Rukshana Shroff
Summary: This study retrospectively analyzed the medical records of pediatric patients with CKD4-5/5D who received SZC treatment. The study found that both short-term and long-term use of SZC can safely and effectively control hyperkalemia and help relax dietary restrictions. This study is important for understanding the application of SZC in pediatric patients with CKD.
PEDIATRIC NEPHROLOGY
(2023)
Meeting Abstract
Pediatrics
Fabio Paglialonga, Rukshana Shroff, Ilona Zagozdzon, Sevcan Bakkaloglu, Ariane Zaloszyc, Augustina Jankauskiene, Alejandro Cruz, Silvia Consolo, Alberto Edefonti
PEDIATRIC NEPHROLOGY
(2022)