☆ 4.5 Article

VISCERAL LEISHMANIASIS ASSOCIATED HEMOPHAGOCYTIC SYNDROME IN PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2009)

Journal

PEDIATRIC INFECTIOUS DISEASE JOURNAL

Volume 28, Issue 8, Pages 753-754

Publisher

LIPPINCOTT WILLIAMS & WILKINS

DOI: 10.1097/INF.0b013e31819c6f3a

Keywords

chronic granulomatous disease; hemophagocytic syndrome; visceral leishmaniasis; interferon-gamma

Categories

Immunology Infectious Diseases Pediatrics

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Abstract

Visceral leishmaniasis is a severe form of infection caused by a parasite endemic along the Mediterranean coast, Complications such as infection-associated hemophagocytic syndrome can occur despite correct therapy. We report visceral leishmaniasis-associated infection-associated hemophagocytic syndrome in 3 patients with chronic granulomatous disease.

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Aebi-Popp, A. Anagnostopoulos, S. Asner, M. Battegay, M. Baumann, E. Bernasconi, J. Boni, D. L. Braun, H. C. Bucher, A. Calmy, M. Cavassini, A. Ciuffi, A. Duppenthaler, G. Dollenmaier, M. Egger, L. Elzi, J. Fehr, J. Fellay, K. Francini, H. Furrer, C. A. Fux, C. Grawe, H. F. Gunthard, D. Haerry, B. Hasse, H. H. Hirsch, M. Hoffmann, I Hosli, M. Huber, C. R. Kahlert, L. Kaiser, O. Keiser, T. Klimkait, L. Kottanattu, R. D. Kouyos, H. Kovari, B. Ledergerber, G. Martinetti, Martinez B. de Tejada, C. Marzolini, K. J. Metzner, N. Mueller, D. Nicca, P. Paioni, G. Pantaleo, M. Perreau, Polli Ch, A. Rauch, C. Rudin, A. U. Scherrer, P. Schmid, R. Speck, M. Stockle, P. Tarr, Thanh M. Lecompte, A. Trkola, P. Vernazza, N. Wagner, G. Wandeler, R. Weber, C. A. Wyler, S. Yerly, Pornpun Wannarit, Pornchai Techakunakorn, Rawiwan Hansudewechakul, Chiang Kham, Vanichaya Wanchaitanawong, Sookchai Theansavettrakul, Mae Sai, Sirisak Nanta, Chaiwat Ngampiyaskul, Siriluk Phanomcheong, Suchat Hongsiriwon, Warit Karnchanamayul, Bhuddasothorn Chacheongsao, Ratchanee Kwanchaipanich, Suparat Kanjanavanit, Somdej Prapinklao, Nareerat Kamonpakorn, Maneeratn Nantarukchaikul, Bhumibol Adulyadej, Prapaisri Layangool, Jutarat Mekmullica, Paiboon Lucksanapisitkul, Sudarat Watanayothin, Narong Lertpienthum, Hat Yai, Boonyarat Warachit, Khon Kaen, Sansanee Hanpinitsak, Nong Khai, Sathit Potchalongsin, Pimpraphai Thanasiri, Sawitree Krikajornkitti, Pornsawan Attavinijtrakarn, Sakulrat Srirojana, Suthunya Bunjongpak, Achara Puangsombat, Sathaporn Na-Rajsima, Pornchai Ananpatharachai, Noppadon Akarathum, Vachira Phuket, Weerasak Lawtongkum, Prapawan Kheunjan, Thitiporn Suriyaboon, Airada Saipanya, Kanchana Than-In-At, Nirattiya Jaisieng, Rapeepan Suaysod, Sanuphong Chailoet, Naritsara Naratee, Suttipong Kawilapat, T. Kaleeva, Y. Baryshnikova, S. Soloha, N. Bashkatova, I. Raus, O. Glutshenko, Z. Ruban, N. Prymak, G. Kiseleva, Alla Volokha, Ruslan Malyuta, H. Bailey, Claire Thorne, Hermione Lyall, Alasdair Bamford, Karina Butler, Katja Doerholt, Conor Doherty, Caroline Foster, Ian Harrison, Julia Kenny, Nigel Klein, Gillian Letting, Paddy McMaster, Fungai Murau, Edith Nsangi, Katia Prime, Andrew Riordan, Fiona Shackley, Delane Shingadia, Sharon Storey, Gareth Tudor-Williams, Anna Turkova, Steve Welch, Intira Jeannie Collins, Claire Cook, Siobhan Crichton, Donna Dobson, Keith Fairbrother, Diana M. Gibb, Ali Judd, Marthe Le Prevost, Nadine Van Looy, Helen Peters, Kate Francis, Claire Thorne, L. Thrasyvoulou, S. Welch, K. Fidler, J. Bernatoniene, F. Manyika, G. Sharpe, B. Subramaniam, R. Hague, V. Price, J. Flynn, A. Cardoso, M. Abou-Rayyah, N. Klein, A. Bamford, D. Shingadia, S. Yeadon, S. Segal, S. Hawkins, M. Dowie, S. Bandi, E. Percival, M. Eisenhut, K. Duncan, L. Anguvaa, L. Wren, T. Flood, A. Pickering, P. McMaster, C. Murphy, J. Daniels, Y. Lees, F. Thompson, A. Williams, B. Williams, S. Pope, S. Libeschutz, L. Cliffe, S. Southall, A. Freeman, H. Freeman, S. Christie, A. Gordon, D. Rosie Hague, L. Clarke, L. Jones, L. Brown, M. Greenberg, M. Greenberg, C. Benson, A. Riordan, L. Ibberson, F. Shackley, S. Patel, J. Hancock, K. Doerholt, K. Prime, M. Sharland, S. Storey, E. G. H. Lyall, C. Foster, P. Seery, G. Tudor-Williams, N. Kirkhope, S. Raghunanan, Julia Kenny, A. Callaghan, A. Bridgwood, P. McMaster, J. Evans, E. Blake, A. Yannoulias

Summary: The study investigated trends and predictors of malignancies among children and young people with HIV. Results showed a decrease in AIDS-defining malignancies (ADM) and an increase in non-AIDS-defining malignancies (NADM) over time. Risk factors for a malignancy diagnosis included male sex, European cohort, vertically acquired HIV, current severe immunosuppression, high viral load, older age, and earlier calendar year for those not on treatment.

AIDS (2021)

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Article Genetics & Heredity

Newborn Screening for SCID: Experience in Spain (Catalonia)

Ana Argudo-Ramirez, Andrea Martin-Nalda, Jose Manuel Gonzalez De Aledo-Castillo, Rosa Lopez-Galera, Jose Luis Marin-Soria, Sonia Pajares-Garcia, Monica Martinez-Gallo, Marina Garcia-Prat, Roger Colobran, Jacques G. Riviere, Yania Quintero, Tatiana Collado, Antonia Ribes, Judit Garcia-Villoria, Pere Soler-Palacin

Summary: Newborn screening for severe combined immunodeficiency (SCID) was initiated in Catalonia in 2017, making it the first region in Spain and Europe to include this testing universally. The results from Catalonia show that early diagnosis and treatment through newborn screening programs can benefit patients with SCID and non-SCID, highlighting the importance of a national screening program in Spain to better understand the exact incidence of SCID.

INTERNATIONAL JOURNAL OF NEONATAL SCREENING (2021)

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