4.5 Article

LOW DOSAGE CIDOFOVIR WITHOUT PROBENECID AS TREATMENT FOR BK VIRUS HAMORRHAGIC CYSTITIS AFTER HEMOPOIETIC STEM CELL TRANSPLANT

Journal

PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 28, Issue 1, Pages 55-57

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0b013e3181812cb9

Keywords

BK virus; cidofovir; probenecid; hemorrhagic cystitis

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We describe a single-center pediatric experience with 1 mg/kg/wk cidofovir without probenecid in 7 children with BK virus-associated hemorrhagic cystitis. Clinical improvement was observed in all cases, without adverse events, although significant reduction of urinary viral load was observed 2 weeks after the end of cidofovir in 5 out of 6 patients who completed the treatment.

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