Article
Endocrinology & Metabolism
Huan-Huan Yang, Fu-Rong Li, Ze-Kun Chen, Meng-Ge Zhou, Li-Feng Xie, Yuan-Yuan Jin, Zhi-Hui Li, Guo-Chong Chen
Summary: This study found that the risk of heart failure increases with a longer duration of diabetes and increasing levels of glycemic control. Considering this finding may contribute to personalized prevention of heart failure in patients with diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Surgery
Nithya Sridhar, Emily Hetzel, Tammy L. Kindel, Jon C. Gould, Rana M. Higgins
Summary: In primary bariatric surgery patients, pre-operative HbA1c levels higher than 8% did not show a significant association with post-operative outcomes. There were differences in procedure selection and post-operative HbA1c levels between patients with pre-operative HbA1c < 8% and > 8%.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Medicine, General & Internal
Raafia Memon, David Levitt, Silvia R. Salgado Nunez del Prado, Kashif Munir, Elizabeth Lamos
Summary: Patients with diabetes mellitus have a basic understanding of HbA1c definition but lack the ability to correlate it with average blood sugar. Additionally, there is a discrepancy between patients' perceived glycemic control and the actual situation.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Medical Laboratory Technology
Dabao He, Wenbin Kuang, Xiaoling Yang, Miao Xu
Summary: The study found that HbA1c levels were significantly lower in patients with HbH disease compared to healthy individuals, while GA showed no significant difference between the two groups. Using HbA1c as a diagnostic criterion for diabetes may lead to a considerable number of diabetic patients with HbH disease being missed. GA, instead of HbA1c, is suitable for monitoring glycemic control in patients with HbH disease and can modify HbA1c's discriminative ability for diagnosing diabetes.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2021)
Article
Pediatrics
Dan Zhou, Li-Jing Deng, Yun-Fei Ling, Meng-Lin Tang
Summary: In children with cyanotic congenital heart disease, a preoperative Hb x SpO(2) value below the lower limit of normal hemoglobin is associated with worse postoperative outcomes, indicating a potential criterion to evaluate preoperative anemia in this population.
FRONTIERS IN PEDIATRICS
(2022)
Article
Endocrinology & Metabolism
Xu Huang, Cheng Qin, Xiaoxu Guo, Feng Cao, Chengchun Tang
Summary: This study investigated the relationship between HbA1c and the incidence of hypertension in a large prospective cohort. The findings suggest that HbA1c is linearly and positively associated with the risk of hypertension, particularly in female, lower education level, and non-obese subgroups. HbA1c can be considered as a predictor for hypertension risk.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Immunology
Ulrika Snygg-Martin, Kok Wai Giang, Mikael Dellborg, Josefina Robertson, Zacharias Mandalenakis
Summary: Patients with congenital heart disease have a higher cumulative incidence of infective endocarditis compared to controls, and this incidence increases with age. The incidence of infective endocarditis varies by age but not by birth year.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Siegfried Geyer, Katharina Fleig, Kambiz Norozi, Lena Roebbel, Thomas Paul, Matthias Mueller, Claudia Dellas
Summary: Patients of congenital heart disease surgery have good prospects for reaching old age, and the educational and occupational performance of patients over 15 years was examined. While some patients retired prematurely or never entered the labour force, their educational and occupational careers proceeded more favorably than expected.
Article
Medical Laboratory Technology
Rihwa Choi, Mi-Jung Park, Sukjung Lee, Sang Gon Lee, Eun Hee Lee
Summary: This study investigated the associations between glycemic biomarkers in Korean adults, demonstrating that fructosamine and GA could be useful adjuncts to HbA1c in Korean patients.
CLINICAL LABORATORY
(2021)
Review
Cell Biology
Kavitha S. Rao, Vasumathi Kameswaran, Benoit G. Bruneau
Summary: Congenital heart defects are common birth defects with unknown causes. Recent development of experimental models, including mouse models and human cellular models, have helped to enhance our understanding of the molecular basis of these defects. The development of cardiac organoids also shows promise in creating more anatomically informative human models of congenital heart defects.
GENES & DEVELOPMENT
(2022)
Article
Endocrinology & Metabolism
Elizabeth Selvin
Summary: The discovery of HbA(1c) as a measure of average glucose exposure was a significant advancement in diabetes care. It is now widely used for monitoring and diagnosing diabetes due to its convenience, reliability, and standardization. Epidemiologic studies have shown strong links between HbA(1c) and complications, making it a cornerstone in modern diabetes care.
Article
Medical Laboratory Technology
Yu Jeong Choi, Hyein Kang, Chan-Ik Cho, John Hoon Rim, Sang-Guk Lee, Jong-Baeck Lim
Summary: The performance of the DxC 700 AU immunoassay device in measuring HbA1c was evaluated. The device showed accuracy, precision, and linearity over a wide concentration range of HbA1c, but caution is needed in cases of high HbF and HbH concentrations.
ANNALS OF LABORATORY MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Giulia Poretti, Stiljan Hoxha, Antonio Segreto, Gardellini Jacopo, Camilla Sandrini, Giuseppe Faggian, Alessandro Varrica, Massimo Chessa, Alessandro Giamberti, Giovanni Battista Luciani
Summary: Cryoablation for supraventricular arrhythmias in ACHD patients is a safe and effective procedure with a low risk of recurrence, and surgical treatment should be considered when further open-heart repair is needed.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Marie Tindborg, Anders Koch, Mikael Andersson, Klaus Juul, Uka Wilhjelm Geisler, Bolette Soborg, Sascha Wilk Michelsen
Summary: The incidence rates of heart disease (HD) and congenital heart disease (CHD) were compared between young Inuit populations in Greenland and Denmark. It was found that the incidence rate of HD was lower in Greenland compared to Denmark, while the incidence rates of CHD were similar in both countries. Individuals of Inuit/mixed ethnicity had a higher risk of both HD and CHD compared to non-Inuit individuals in both countries.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Shannon L. Son, Lauren L. Hosek, Miranda C. Stein, Amanda A. Allshouse, Anna B. Catino, Arvind K. Hoskoppal, Daniel A. Cox, Kevin J. Whitehead, Ian M. Lindsay, Sean Esplin, Torri D. Metz
Summary: This retrospective longitudinal cohort study found an association between pregnancy and subsequent long-term adverse cardiovascular outcomes in individuals with congenital heart disease. These findings can provide important information for counseling and guidance of individuals with congenital heart disease who are considering pregnancy.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Yassaman Vafai, Edwina H. Yeung, Rajeshwari Sundaram, Melissa M. Smarr, Nicole Gerlanc, William A. Grobman, Daniel Skupski, Edward K. Chien, Stefanie N. Hinkle, Roger B. Newman, Deborah A. Wing, Angela C. Ranzini, Anthony Sciscione, Jagteshwar Grewal, Cuilin Zhang, Katherine L. Grantz
Summary: This study investigated the quantity and type of supplements and medications used during pregnancy in a low-risk cohort and found that supplement intake was nearly universal, while medication use differed by race/ethnicity.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Maria Andrikopoulou, Elisa T. Bushman, Madeline M. Rice, William A. Grobman, Uma M. Reddy, Robert M. Silver, Yasser Y. El-Sayed, Dwight J. Rouse, George R. Saade, John M. Thorp, Suneet P. Chauhan, Maged M. Costantine, Edward K. Chien, Brian M. Casey, Sindhu K. Srinivas, Geeta K. Swamy, Hyagriv N. Simhan
Summary: This study aimed to evaluate the impact of different cervical ripening methods on maternal and neonatal outcomes among low-risk nulliparous individuals. The results showed that compared to using prostaglandin only, using Foley catheter with prostaglandin or Foley catheter alone was associated with a lower risk of adverse neonatal outcomes. Moreover, labor induction with Foley catheter and concurrent oxytocin resulted in the shortest duration of labor and delivery stay.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Letter
Obstetrics & Gynecology
Katherine L. Grantz, Jagteshwar Grewal, Sungduk Kim, William A. Grobman, Roger B. Newman, John Owen, Anthony Sciscione, Daniel Skupski, Edward K. Chien, Deborah A. Wing, Ronald J. Wapner, Angela C. Ranzini, Michael P. Nageotte, Sabrina Craigo, Stefanie N. Hinkle, Mary E. D'Alton, Dian He, Fasil Tekola-Ayele, Mary L. Hediger, Germaine M. Buck Louis, Cuilin Zhang, Paul S. Albert
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Maged M. Costantine, Madeline Murguia Rice, Mark B. Landon, Michael W. Varner, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, Dwight J. Rouse, Alan T. N. Tita, John M. Thorp, Edward K. Chien, Alan M. Peaceman, Sean C. Blackwell
Summary: This study aims to evaluate whether the values and shape of the glucose curve during an oral glucose tolerance test (OGTT) in pregnancy can identify women at risk of developing hypertension later in life. The results suggest that the 2-hour OGTT value was positively associated with the primary outcome, while the 3-hour OGTT value was negatively associated. Furthermore, a monophasic OGTT response was associated with an increased risk of hypertension.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Jessica Pippen, Bethany Stetson, Lindsay Doherty, Michael W. Varner, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, Dwight J. Rouse, Alan T. N. Tita, John M. Thorp, Edward K. Chien, George R. Saade, Sean C. Blackwell
Summary: The study found that birthweight and early infancy feeding practices are not associated with alterations in leptin and adiponectin levels in children of women with mild GDM.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Michal Fishel Bartal, Ashish Premkumar, Madeline Murguia Rice, Uma M. Reddy, Alan T. N. Tita, Robert M. Silver, Yasser Y. El-Sayed, Ronald J. Wapner, Dwight J. Rouse, George R. Saade, John M. Thorp, Maged M. Costantine, Edward K. Chien, Brian M. Casey, Sindhu K. Srinivas, Geeta K. Swamy, Hyagriv N. Simhan
Summary: This secondary analysis of a randomized trial found that almost 14% of low-risk nulliparous women who were expectantly managed at or after 39 weeks developed hypertensive disorders of pregnancy (HDP), and they were more likely to experience adverse maternal outcomes compared to those who did not develop HDP.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Dwight J. Rouse, Lida M. Fette, Brenna L. Hughes, George R. Saade, Mara J. Dinsmoor, Uma M. Reddy, Robert Pass, Donna Allard, Gail Mallett, Rebecca G. Clifton, Frances M. Saccoccio, Sallie R. Permar, Cynthia Gyamfi-Bannerman, Michael W. Varner, William H. Goodnight, Alan T. N. Tita, Maged M. Costantine, Geeta K. Swamy, Kent D. Heyborne, Edward K. Chien, Suneet P. Chauhan, Yasser Y. El-Sayed, Brian M. Casey, Samuel Parry, Hyagriv N. Simhan, Peter G. Napolitano, George A. Macones
Summary: We developed and internally validated a non-invasive method for predicting congenital CMV infection after primary maternal CMV infection. The models showed moderate discriminatory ability and can be useful for patient counseling and decision making.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Michelle P. Debbink, Lynda G. Ugwu, William A. Grobman, Uma M. Reddy, Alan T. N. Tita, Yasser Y. El-Sayed, Ronald J. Wapner, Dwight J. Rouse, George R. Saade, John M. Thorp, Suneet P. Chauhan, Maged M. Costantine, Edward K. Chien, Brian M. Casey, Sindhu K. Srinivas, Geeta K. Swamy, Hyagriv N. Simhan
Summary: This study found that non-Hispanic Black and Hispanic low-risk nulliparous individuals at term undergo cesarean birth more frequently than low-risk non-Hispanic White nulliparous individuals. This difference accounts for a modest portion of excess maternal morbidity.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Beth A. Plunkett, Steven J. Weiner, George R. Saade, Michael A. Belfort, Sean C. Blackwell, John M. Thorp, Alan T. N. Tita, Russell S. Miller, David S. McKenna, Edward K. S. Chien, Dwight J. Rouse, Yasser Y. El-Sayed, Yoram Sorokin, Steve N. Caritis
Summary: ST changes in fetal ECG occur more frequently in fetuses of diabetic mothers during labor. This may indicate fetal cardiac hypoxia.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Roger B. Newman, Danielle R. Stevens, Kelly J. Hunt, William A. Grobman, John Owen, Anthony Sciscione, Ronald J. Wapner, Daniel Skupski, Edward K. Chien, Deborah A. Wing, Angela C. Ranzini, Manuel Porto, Katherine L. Grantz
Summary: This study aimed to evaluate fetal biometrics as predictors of shoulder dystocia (SD) in a low-risk obstetrical population. The results showed that, apart from the use of epidural anesthesia, there were no significant associations between sociodemographic or maternal anthropometrics and SD in this low-risk population. Fetal biometrics had limited ability to predict SD and lack clinical usefulness.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Sport Sciences
Susanna D. Mitro, Shyamal Peddada, Jessica L. Gleason, Dian He, Brian Whitcomb, Lindsey Russo, Jagteshwar Grewal, Cuilin Zhang, Samrawit F. Yisahak, Stefanie N. Hinkle, Germaine M. Buck Louis, Roger Newman, William Grobman, Anthony C. Sciscione, John Owen, Angela Ranzini, Sabrina Craigo, Edward Chien, Daniel Skupski, Deborah Wing, Katherine L. Grantz
Summary: This study investigated longitudinal activity during singleton and twin pregnancies by activity domain and maternal characteristics. The findings showed that household/caregiving activity accounted for the largest fraction of reported activity, followed by occupational activity. However, overall activity levels declined significantly during pregnancy. Non-Hispanic Black women reported higher activity levels than other racial/ethnic groups at baseline. Nulliparous women and women with singleton gestations reported lower activity levels compared to parous women and women with twins, respectively.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Obstetrics & Gynecology
Maged M. Costantine, Grecio J. Sandoval, William A. Grobman, Uma M. Reddy, Alan T. N. Tita, Robert M. Silver, Yasser Y. El-Sayed, Ronald J. Wapner, Dwight J. Rouse, George R. Saade, John M. Thorp, Suneet P. Chauhan, Edward K. Chien, Brian M. Casey, Sindhu K. Srinivas, Geeta K. Swamy, Hyagriv N. Simhan
Summary: Among low-risk nulliparous people, higher BMI was associated with a longer time from admission to delivery, longer total hospital LOS, and more frequent utilization of intrapartum and postpartum resources.
OBSTETRICS AND GYNECOLOGY
(2022)
Letter
Obstetrics & Gynecology
Katherine L. Grantz, Jagteshwar Grewal, Sungduk Kim, William A. Grobman, Roger B. Newman, John Owen, Anthony Sciscione, Daniel Skupski, Edward K. Chien, Deborah A. Wing, Ronald J. Wapner, Angela C. Ranzini, Michael P. Nageotte, Sabrina Craigo, Stefanie N. Hinkle, Mary E. D'Alton, Dian He, Fasil Tekola-Ayele, Mary L. Hediger, Germaine M. Buck Louis, Cuilin Zhang, Paul S. Albert
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Erin M. Cleary, Douglas A. Kniss, Lida M. Fette, Brenna L. Hughes, George R. Saade, Mara J. Dinsmoor, Uma M. Reddy, Cynthia Gyamfi-Bannerman, Michael W. Varner, William H. Goodnight, Alan T. N. Tita, Geeta K. Swamy, Kent D. Heyborne, Edward K. Chien, Suneet P. Chauhan, Yasser Y. El-Sayed, Brian M. Casey, Samuel Parry, Hyagriv N. Simhan, Peter G. Napolitano
Summary: In a cohort of parturients with primary CMV infection, nicotine exposure was not associated with offspring hearing dysfunction assessed with DPOAEs.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Ashley N. Battarbee, Lisa Mele, Mark B. Landon, Michael W. Varner, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, Dwight J. Rouse, John M. Thorp, Edward K. Chien, George Saade, Beth A. Plunkett, Sean C. Blackwell
Summary: The objective of this study was to evaluate the association between mild gestational diabetes mellitus (GDM) and obesity with metabolic and cardiovascular markers 5 to 10 years after pregnancy. The results showed that prior GDM and obesity were associated with increased insulin resistance but no consistent cardiovascular dysfunction or alterations in insulin secretion.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
