☆ 4.4 Article

Variable response to propranolol treatment of kaposiform hemangioendothelioma, tufted angioma, and Kasabach-Merritt phenomenon

PEDIATRIC BLOOD & CANCER (2012)

Journal

PEDIATRIC BLOOD & CANCER

Volume 59, Issue 5, Pages 934-938

Publisher

WILEY-BLACKWELL

DOI: 10.1002/pbc.24103

Keywords

Kasabach-Merritt; kaposiform hemangioendothlioma; propranolol; treatment; tufted angioma; vascular tumor

Categories

Oncology Hematology Pediatrics

Funding

National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS/NIH) [K23AR060274]

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Abstract

Propranolol is a non-selective beta-adrenergic antagonist successfully used in a case of kaposiform hemangioendothelioma (KHE) associated with KasabachMerritt phenomenon (KMP). We report 11 patients treated with propranolol for KHE and the related variant tufted angioma (TA), six of whom also had KMP. The varied responses to treatment, with only 36% responding in our series, demonstrate the need for further study of this medication before routine use for these indications. Pediatr Blood Cancer 2012; 59: 934938. (C) 2012 Wiley Periodicals, Inc.

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Article Medicine, General & Internal

Prognostic value of pre-operative mean corpuscular volume (MCV) in colorectal cancer

Poorya Shokuhi, Niall J. O'Sullivan, Hugo C. Temperley, Thomas Russell, Philip D. Mcentee, Brian J. Mehigan, Paul H. Mccormick, David Gallagher, Charles Gillham, John Kennedy, Michael E. Kelly, John O. Larkin

Summary: This study investigated the relationship between high pre-operative mean corpuscular volume (MCV) and post-operative outcomes and disease recurrence in colorectal cancer (CRC). The results showed that high pre-operative MCV did not predict negative post-operative or oncological outcomes.

IRISH JOURNAL OF MEDICAL SCIENCE (2023)

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Article Surgery

Multisocietal European consensus on the terminology, diagnosis, and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE

Ajith K. Siriwardena, Alejandro Serrablo, Asmund Avdem Fretland, Stephen J. Wigmore, Jose Manuel-Angel, Hassan Z. Malik, Stefan Staettner, Kjetil Soreide, Oded Zmora, Martijn Meijerink, Nikolaos Kartalis, Mickael Lesurtel, Kees Verhoef, Anita Balakrishnan, Thomas Gruenberger, Eduard Jonas, John Devar, Saurabh Jamdar, Robert Jones, Mohammad Abu Hilal, Bodil Andersson, Karim Boudjema, Saifee Mullamitha, Laurents Stassen, Bobby V. M. Dasari, Adam E. Frampton, Luca Aldrighetti, Gianluca Pellino, Pamela Buchwald, Bengi Gurses, Nir Wasserberg, Birgit Gruenberger, Harry V. M. Spiers, William Jarnagin, Jean-Nicholas Vauthey, Norihiro Kokudo, Sabine Tejpar, Andres Valdivieso, Rene Adam

Summary: This article presents a practical framework for managing patients with synchronous colorectal cancer and liver metastases. It discusses the terminology, diagnosis, and management, providing guidance and recommendations for clinicians.

BRITISH JOURNAL OF SURGERY (2023)

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