Journal
PEDIATRIC BLOOD & CANCER
Volume 60, Issue 3, Pages 357-362Publisher
WILEY PERIODICALS, INC
DOI: 10.1002/pbc.24407
Keywords
Africa; Burkitt lymphoma; limited resources; treatment
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Treatment recommendations for endemic Burkitt lymphoma (BL) in settings with only minimum requirements for curative treatment (PODC setting 1) are described. The reported cure rate for endemic BL is usually <50%. Facilities within setting 1 differ. Three treatment schedules are proposed based on: (1) when accurate staging is not possible, (2) when staging is possible and for (3) relapses and poor responders to primary therapy. A literature review and personal experience were used to formulate the recommendations. Recorded 1-year event free survival was 48% for treatment 1, 61% for treatment 2, and 35% for the rescue treatment. Pediatr Blood Cancer 2013; 60: 357362. (C) 2012 Wiley Periodicals, Inc.
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