Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors

Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer

(2010) Avaniyapuram Kannan Murugan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IDH1 Mutations in Gliomas: When an Enzyme Loses Its Grip

(2010) Christian Frezza et al.   CANCER CELL

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

(2010) Patrick S. Ward et al.   CANCER CELL

An overview of L-2-hydroxyglutarate dehydrogenase gene (L2HGDH) variants: a genotype-phenotype study

(2010) Marjan E. Steenweg et al.   HUMAN MUTATION

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

(2010) Stefan Gross et al.   JOURNAL OF EXPERIMENTAL MEDICINE

L-2-Hydroxyglutaric Aciduria and Multiple Acyl-coenzyme A Dehydrogenase Deficiency Are Distinct Metabolic Disorders

(2010) Dinesh Rakheja   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Somatic Mutations ofIDH1andIDH2in the Leukemic Transformation of Myeloproliferative Neoplasms

(2010) Anthony Green et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wilms Tumor in a Child with L-2-hydroxyglutaric Aciduria

(2010) Robert E. Rogers et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

IDH1mutations at residue p.R132 (IDH1R132) occur frequently in high-grade gliomas but not in other solid tumors

(2009) Fonnet E. Bleeker et al.   HUMAN MUTATION

Evidence for genetic heterogeneity in D-2-hydroxyglutaric aciduria

(2009) Martijn Kranendijk et al.   HUMAN MUTATION

L-2-Hydroxyglutaric Aciduria and Brain Tumors

(2009) Nalan Yazici et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

Two eminently treatable genetic metabolic myopathies

(2009) Woon-Chee Yee   NEUROLOGY INDIA

Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

(2009) Elaine R. Mardis et al.   NEW ENGLAND JOURNAL OF MEDICINE

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wilms tumor genetics: Mutations inWT1,WTX, andCTNNB1 account for only about one-third of tumors

(2008) E. Cristy Ruteshouser et al.   GENES CHROMOSOMES & CANCER

l-2-Hydroxyglutaric aciduria, a disorder of metabolite repair

(2008) E. Van Schaftingen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review

(2008) Mahdi Aghili et al.   JOURNAL OF NEURO-ONCOLOGY

L-2-Hydroxyglutaric Aciduria and Brain Tumors in Children with Mutations in theL2HGDHGene: Neuroimaging Findings

(2008) G. Haliloglu et al.   NEUROPEDIATRICS

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Risk of sudden death and acute life-threatening events in patients with glutaric acidemia type II

(2007) Brad Angle et al.   MOLECULAR GENETICS AND METABOLISM