Risk Factors for Hospital Readmission Within 30 Days: A New Quality Measure for Children With Sickle Cell Disease

Background. The National Association of Children's Hospitals and Related Institutions (NACHRI) established hospital readmission within 30 clays as a benchmark for quality care in children with Sickle Cell Disease (SCD). Among children with SCD, limited data exists to identify risk factors for readmission and whether they are modifiable. Procedure. We performed a retrospective cohort study 10 identify risk factors for readmission. All admissions for children with SCD in a 1-year period were reviewed; cases were defined as children with SCD readmitted within 30 clays after their first admission during the Study period and controls, children with SCD who were not readmitted. Results. We identified 30 cases and 70 controls. No difference in demographic data Was found between groups. The most common admission and readmission diagnosis was pain, 78 and 70%, respectively. The greatest risk factor for readmission was no outpatient hematology follow-up within 30 days of discharge (OR 7.7, 95% CI 2.4-24.4). A diagnosis of asthma was also a risk factor for readmission (OR 2.9, 95%, C1 1.2-7.3). Patients who required supplemental oxygen to maintain saturations in the normal range and were oil loom air for <= 24 hr at discharge were also more likely to be readmitted (OR 3.3, 95% CI 1.1-9.7). Multivariate analysis identified lack of outpatient follow-up and disease severity, defined as >= 3 admissions in the previous 12 months as predictors for readmission (R-2=0.41). Conclusions. potentially modifiable risk factors exist to decrease the rate of readmission of children with SCD admitted to the hospital for pain. Pediatr Blood Cancer 2009; 52:481-485. (c) 2008 Wiley-Liss, Inc.