Journal
PEDIATRIC ANESTHESIA
Volume 22, Issue 2, Pages 150-155Publisher
WILEY
DOI: 10.1111/j.1460-9592.2011.03707.x
Keywords
tramadol; sedation; endoscopy
Categories
Ask authors/readers for more resources
Aim: This study was conducted to compare the efficacy and safety of tramadol with those of fentanyl and to evaluate the impact of age in pediatric patients undergoing upper gastrointestinal endoscopy (UGIE). Methods: Eighty patients with ASA I-II, aged 1-16 years, undergoing UGIE were included in this study. Baseline anesthesia was maintained with 1 mg.kg(-1) propofol, and then, the patients were randomly assigned to receive 2 mu g.kg(-1) fentanyl (group F, n = 40) or 2 mg.kg(-1) tramadol (group T, n = 40). Additional propofol, 0.5-1 mg.kg(-1), was administered when needed. Heart rate, mean arterial pressure, oxygen saturation (SpO(2)), and sedation scores were recorded at baseline, induction, and every 5 min. Endoscopy duration, recovery time, and adverse effects were recorded. The data were separated for subgroup analyses based on the age of 0-2, 2-12, and over 12 years. Results: Fentanyl significantly decreased the saturation at induction, 5th min and 10th min in patients of 0-2 years; at 5th and 10th min in 212 years; and at 5th min in > 12 years. In all age subgroups, sedation scores at 10th, 15th, and 20th min, the overall frequency of adverse effects, and the recovery time were significantly lower in group T compared with group F. Conclusion: Tramadol in pediatric patients undergoing UGIE provided sedation as efficient as fentanyl with a better hemodynamic and respiratory stability and provided a superior safety and tolerance in younger children.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available