Review
Cardiac & Cardiovascular Systems
Krishnan Warrior, Daniel F. Dilling
Summary: Lymphangioleiomyomatosis (LAM) is a rare cystic lung disease with respiratory symptoms and extra-thoracic manifestations. Lung transplantation can improve the life quality of LAM patients with end-stage lung disease, but there are unique considerations and complications associated with LAM. This review provides an overview of evaluation, management, and outcomes for LAM patients undergoing lung transplantation.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Oncology
Ryota Hamada, Yohei Oshima, Susumu Sato, Yuji Yoshioka, Tatsuya Sato, Manabu Nankaku, Tadakazu Kondo, Toyofumi F. Chen-Yoshikawa, Ryosuke Ikeguchi, Daisuke Nakajima, Hiroshi Date, Shuichi Matsuda
Summary: This study investigated the long-term changes in physical functions of patients who underwent lung transplantation for LONIPCs after allo-HSCT. Results showed that while dyspnea scores and performance status improved after 2 years, physical functions such as knee extensor strength and exercise tolerance gradually recovered over the course of 2 years, with exercise tolerance being influenced by recovery in %VC and KES.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Surgery
Hidenao Kayawake, Toyofumi F. Chen-Yoshikawa, Satona Tanaka, Yuka Tanaka, Hideki Ohdan, Yojiro Yutaka, Yoshito Yamada, Akihiro Ohsumi, Daisuke Nakajima, Masatsugu Hamaji, Hiroto Egawa, Hiroshi Date
Summary: This study found that the R-type single nucleotide polymorphisms in the FCGR2A gene are associated with infectious complications after lung transplantation, suggesting that recipients with the H/R or R/R genotype may require closer attention to infectious complications.
TRANSPLANT INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Ji Zhang, Dong Liu, Bingqing Yue, Le Ban, Min Zhou, Hongmei Wang, Jian Lv, Bo Wu, Zhenguo Zhai, Kai-Feng Xu, Wenhui Chen, Jingyu Chen
Summary: This study summarized the clinical data of 25 patients with pulmonary LAM who underwent lung transplantation at two hospitals in China between 2010 and 2018. The study highlighted the importance of lung transplantation for LAM patients in the Asian population and emphasized the need for further research on sirolimus use and LAM-related complications.
FRONTIERS IN MEDICINE
(2021)
Article
Respiratory System
Peter Riddell, Ram Vasudevan-Nampoothiri, Jin Ma, Lianne G. Singer, Jeff H. Lipton, Stephen C. Juvet
Summary: This study found an increased risk of post-LTx mortality in recipients with previous allo-HSCT, especially related to infections. The 1-year survival rate post-LTx was similar to re-LTx recipients, but the conditional 1-year survival rate was lower. Therefore, optimization of post-LTx immunosuppressive and antimicrobial strategies should be considered in this patient population.
RESPIRATORY RESEARCH
(2021)
Article
Medicine, General & Internal
Anna Munoz-Fos, Paula Moreno, Francisco Javier Gonzalez, Eloisa Ruiz, Jose Manuel Vaquero, Carlos Baamonde, Francisco Cerezo, Javier Algar, Ricard Ramos-Izquierdo, Angel Salvatierra, Antonio Alvarez
Summary: This study retrospectively analyzed patients who received lung transplantation between 2007 and 2019, and found that despite the advances in lung transplantation practice, the incidence and risk factors for airway complications have not changed. Graft dysfunction, infected environment, and the need for prolonged mechanical ventilation remain major risk factors for airway complications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Thomas S. Decates, Andries E. Budding, Peter J. Velthuis, Yara Bachour, Lisanne W. Wolters, Leonie W. Schelke, Tamar E. C. Nijsten, Frank B. Niessen
Summary: This study found that the treatment algorithm for late-onset inflammatory adverse events with soft-tissue fillers depends on the causative factor: immunologic or bacterial. The results showed a high level of Gram-positive bacteria in fillers, suggesting that they were introduced during injection. Contamination from skin microbiota during sampling was excluded.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Yuriko Terada, Tsuyoshi Takahashi, Ramsey R. Hachem, Jingxia Liu, Chad A. Witt, Derek E. Byers, Rodrigo Vazquez Guillamet, Hrishikesh S. Kulkarni, Ruben G. Nava, Benjamin D. Kozower, Bryan F. Meyers, Michael K. Pasque, G. Alexander Patterson, Daniel Kreisel, Varun Puri
Summary: This study analyzed a lung transplant database and found that some single lung transplants were performed after aborted double lung transplants, with acceptable long-term outcomes.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Yugo Tanaka, Hiroyuki Yamamoto, Masami Sato, Shinichi Toyooka, Morihito Okada, Shunsuke Endo, Yukio Sato, Kenji Suzuki, Yoshimasa Maniwa, Eriko Fukuchi, Hiroaki Miyata, Masayuki Chida
Summary: The study showed that preoperative cumulative smoking dose is associated with postoperative mortality and complications after lobectomy for primary lung cancer. The risk of adverse outcomes increases with higher pack-years of smoking before surgery.
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Marco Schiavon, Stefania Camagni, Federico Venuta, Lorenzo Rosso, Massimo Boffini, Francesco Parisi, Alessandro Bertani, Federica Meloni, Piero Paladini, Eleonora Faccioli, Michele Colledan, Daniele Diso, Margherita Cattaneo, Fabrizio Scalini, Sara Alfieri, Domenica Giunta, Monica Morosini, Luca Luzzi, Giulia Lorenzoni, Andrea Dell'Amore, Federico Rea
Summary: This study analyzed the experience of pediatric lung transplantation in Italy and found that the outcomes were comparable to current literature. Attention should be paid to the Oto score and recipient body mass index, and adult donors and graft reductions can be safely used to expand the donor pool.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Infectious Diseases
Eun-Ki Min, Juhan Lee, Su Jin Jeong, Deok-Gie Kim, Seung Hyuk Yim, Mun Chae Choi, Dong Jin Joo, Myoung Soo Kim, Jae Geun Lee
Summary: The risk factors for late-onset Pneumocystis jirovecii pneumonia (PCP) after liver transplantation (LT) have been analyzed in this study. Age >= 65 years at LT, cytomegalovirus infection, steroid pulse therapy, hepatocellular carcinoma recurrence, and lymphocytopenia were identified as independent risk factors for PCP. Targeted prophylaxis considering these risk factors could improve the prevention of this potentially lethal complication.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Clinical Neurology
Dolly Reyes-Dumeyer, Kelley Faber, Badri Vardarajan, Alison Goate, Alan Renton, Michael Chao, Brad Boeve, Carlos Cruchaga, Margaret Pericak-Vance, Jonathan L. Haines, Roger Rosenberg, Debby Tsuang, Robert A. Sweet, David A. Bennett, Robert S. Wilson, Tatiana Foroud, Richard Mayeux
Summary: The NIA-LOAD FBS is the largest collection of familial Alzheimer's disease worldwide, and it focuses on studying the genetic etiology of the disease. The study has identified the association between APOE genotype and age-at-onset, and it has also found novel and known variants associated with early- and late-onset Alzheimer's disease and frontotemporal dementia.
ALZHEIMERS & DEMENTIA
(2022)
Article
Endocrinology & Metabolism
Yongin Cho, Hye-Sun Park, Byung Wook Huh, Seong Ha Seo, Da Hea Seo, Seong Hee Ahn, Seongbin Hong, Young Ju Suh, So Hun Kim
Summary: This study compares the prevalence and risk of diabetic complications between people with young-onset and late-onset type 2 diabetes mellitus. The results show that people with young-onset type 2 diabetes have a higher prevalence of complications, particularly neuropathy.
DIABETES & METABOLISM
(2022)
Article
Medicine, General & Internal
Jalal Heshmatnia, Maryam Sadat Mirenayat, Mitrasadat Rezaei, Felix Bongomin, Mehrdad Bakhshayeshkaram, Payam Tabarsi, Kambiz Sheikhy, Vida Mortezaee
Summary: Pulmonary lymphangioleiomyomatosis (LAM) is a rare disease primarily affecting women of childbearing age, potentially leading to respiratory failure, with lung transplantation being a treatment option for end-stage disease. While LAM-related complications are common, recurrence of LAM following transplantation is rare.
ARCHIVES OF IRANIAN MEDICINE
(2021)
Article
Multidisciplinary Sciences
Shihwan Chang, Ji Soo Choi, Ah Young Leem, Su Hwan Lee, Sang Hoon Lee, Song Yee Kim, Kyung Soo Chung, Ji Ye Jung, Young Ae Kang, Young Sam Kim, Jin Gu Lee, Hyo Chae Paik, Hyo Sup Shim, Eun Hye Lee, Moo Suk Park
Summary: This study aims to describe the clinical features of LAM in Korean patients and identify factors associated with progressive disease. The study found that pneumothorax and abdominal lymphadenopathy are common features, and some patients had stable disease after initial treatment. Patients treated with sirolimus had a higher proportion of stable disease, while baseline lung function and lung function changes were associated with disease progression.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Tomoyuki Nakagiri, Soichiro Funaki, Yoshihisa Kadota, Yukiyasu Takeuchi, Hiroyuki Shiono, Akinori Akashi, Meinoshin Okumura
ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY
(2014)
Editorial Material
Cardiac & Cardiovascular Systems
Tomoyuki Nakagiri, Masayoshi Inoue, Junichiro Nakagawa, Meinoshin Okumura
ANNALS OF THORACIC SURGERY
(2011)
Article
Immunology
Jihye Lee, Tomoyuki Nakagiri, Daisuke Kamimura, Masaya Harada, Takahiro Oto, Yoshiyuki Susaki, Yasushi Shintani, Masayoshi Inoue, Shinichiro Miyoshi, Eiichi Morii, Toshio Hirano, Masaaki Murakami, Meinoshin Okumura
INTERNATIONAL IMMUNOLOGY
(2013)
Article
Surgery
Tomoyuki Nakagiri, Gregor Warnecke, Murat Avsar, Stefanie Thissen, Bianca Kruse, Christian Kuehn, Petra Ziehme, Ann-Kathrin Knoefel, Nodir Madrahimov, Meinoshin Okumura, Yoshiki Sawa, Jens Gottlieb, Andre R. Simon, Axel Haverich, Martin Strueber
Article
Surgery
Tomoyuki Nakagiri, Masayoshi Inoue, Masato Minami, Yasushi Hoshikawa, Masayuki Chida, Toru Bando, Takahiro Oto, Takeshi Shiraishi, Naoya Yamasaki, Juntaro Ashikari, Yoshiki Sawa, Meinoshin Okumura
Article
Surgery
Tomoyuki Nakagiri, Masayoshi Inoue, Yasushi Shintani, Soichiro Funaki, Tomohiro Kawamura, Masato Minami, Mitsunori Ohta, Yoshihisa Kadota, Hiroyuki Shiono, Meinoshin Okumura
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2015)
Article
Immunology
T. Nakagiri, M. Inoue, M. Minami, Y. Shintani, M. Okumura
TRANSPLANTATION PROCEEDINGS
(2012)
Article
Cardiac & Cardiovascular Systems
Tomoyuki Nakagiri, Noriyoshi Sawabata, Souichirou Funaki, Masayoshi Inoue, Yoshihisa Kadota, Yasushi Shintani, Meinoshin Okumura
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2011)
Article
Respiratory System
Tomoyuki Nakagiri, Sabine Wrenger, Kokilavani Sivaraman, Fabio Ius, Tobias Goecke, Patrick Zardo, Veronika Grau, Tobias Welte, Axel Haverich, Ann-Kathrin Knofel, Sabina Janciauskiene
Summary: Therapy with AAT suppresses acute rejection after LuTx in a mouse model, with beneficial effects involving anti-protease and immunomodulatory activities of AAT.
RESPIRATORY RESEARCH
(2021)
Article
Oncology
Tomoyuki Nakagiri, Tomio Nakayama, Toshiteru Tokunaga, Akemi Takenaka, Hidenori Kunoh, Hiroto Ishida, Yasuhiko Tomita, Shin-ichi Nakatsuka, Harumi Nakamura, Jiro Okami, Masahiko Higashiyama
Article
Oncology
Tomoyuki Nakagiri, Tornio Nakayama, Toshiteru Tokunaga, Akemi Takenaka, Hidenori Kunoh, Hiroto Ishida, Yasuhiko Tomita, Shin-ichi Nakatsuka, Harumi Nakamura, Jiro Okami, Masahiko Higashiyama
Article
Cardiac & Cardiovascular Systems
Tomoyuki Nakagiri, Noriyoshi Sawabata, Eiichi Morii, Masayoshi Inoue, Yasushi Shintani, Soichiro Funaki, Meinoshin Okumura
GENERAL THORACIC AND CARDIOVASCULAR SURGERY
(2014)
Article
Medicine, General & Internal
Tomoyuki Nakagiri, Meinoshin Okumura
CLINICAL CASE REPORTS
(2013)
Article
Oncology
Tomoyuki Nakagiri, Toshiteru Tokunaga, Hidenori Kunoh, Shingo Noura, Hiroto Ishida, Norikatsu Miyoshi, Masayuki Ohue, Jiro Okami, Masahiko Higashiyama
CASE REPORTS IN ONCOLOGY
(2018)