Article
Allergy
Nian-Rong Wang, Shi-Jian Liu, Gui-Yuan Xiao, Hua Zhang, Yu-Jie Huang, Li Wang, Chun-Yan He
Summary: This study investigated the relationship between food allergy and pregnant women and infants in western China. The results showed that winter birth and sufficient levels of vitamin D-3 were independent risk factors for food allergy in infants.
WORLD ALLERGY ORGANIZATION JOURNAL
(2022)
Article
Pediatrics
Andrea Bassi, Fausto Pedaci, Teresa Oranges, Chiara Azzari, Luisa Galli, Silvia Ricci, Cesare Filippeschi, Elisabetta Venturini
Summary: In this study, a significant correlation was found between higher serum IgE levels and the chronic-relapsing course of Gianotti Crosti syndrome (GCS) in children. Those with chronic relapses had significantly elevated IgE levels compared to those without relapses, suggesting a potential relationship between IgE levels and the clinical course of GCS.
FRONTIERS IN PEDIATRICS
(2021)
Article
Pediatrics
Ling-Sai Chang, Jou-Hui Li, Pei-Ming Wang, Chih-Fang Huang, Ho-Chang Kuo
Summary: The study found that there was no association between total IgE levels and body height in preschool-aged children, but there was a correlation with allergen-specific IgE levels. Further research is needed to replicate these results in follow-up allergic cohorts.
Article
Immunology
Lili Zhou, Yuan Li, Zhufei Xu, Xuyun Peng, Xiaoyan Gong, Lin Yang
Summary: This study found that children with Mycoplasma pneumoniae pneumonia and higher serum IgE levels tend to have more severe clinical symptoms and complications, suggesting IgE could serve as a biomarker for complications following MP infection.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Allergy
Noriko Sato, Fumiya Yamaide, Taiji Nakano, Syuji Yonekura, Yoshitaka Okamoto, Naoki Shimojo
Summary: The study examined the association between cord blood TARC and the development of allergic diseases in children. It found that cTARC levels were associated with early onset allergic diseases and allergen sensitization, suggesting that the atopic march may start in fetal life and be reflected in cTARC levels at birth.
ALLERGOLOGY INTERNATIONAL
(2023)
Article
Allergy
Noriyuki Yanagida, Sakura Sato, Ken-ichi Nagakura, Kyohei Takahashi, Naoko Fusayasu, Yoko Miura, Takaaki Itonaga, Kiyotake Ogura, Motohiro Ebisawa
Summary: This study investigated the risk factors for low threshold doses of food allergens and their relationship with specific immunoglobulin E (sIgE) levels. The results showed that high sIgE levels were associated with an increased risk of low threshold dose reactions and anaphylaxis. The potential risks of anaphylaxis should be considered during food allergy testing.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Article
Immunology
Cristina Frias Sartorelli de Toledo Piza, Carolina Sanchez Aranda, Dirceu Sole, Stephen Jolles, Antonio Condino-Neto
Summary: This study analyzed serum protein electrophoresis results in children and adolescents under 18 years old, finding a correlation between calculated globulin and serum gamma globulin fraction with IgG levels. These indicators can serve as screening tools for early diagnosis of antibody deficiency, reducing diagnostic delays and improving patient outcomes.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Allergy
Angela Gaspar, Natacha Santos, Emilia Faria, Ana Margarida Pereira, Eva Gomes, Rita Camara, Rodrigo Rodrigues-Alves, Luis-Miguel Borrego, Isabel Carrapatoso, Leonor Carneiro-Leao, Mario Morais-Almeida, Luis Delgado, Elisa Pedro, Manuel Branco-Ferreira
Summary: This study found that in the Portuguese pediatric population, food is the leading cause of anaphylaxis, with undertreatment with adrenaline and high recurrence rates highlighting the need for improved diagnosis and therapeutic management of this life-threatening condition.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2021)
Article
Cell & Tissue Engineering
Jessica M. Sun, Laura E. Case, Mohamad A. Mikati, Joan M. Jasien, Colleen McLaughlin, Barbara Waters-Pick, Gordon Worley, Jesse Troy, Joanne Kurtzberg
Summary: Studies suggest that appropriately dosed allogeneic sibling HLA-matched umbilical cord blood infusion has the potential to improve motor function in young children with cerebral palsy. This treatment is well tolerated and shows no adverse events related to the infusion.
STEM CELLS TRANSLATIONAL MEDICINE
(2021)
Article
Agriculture, Dairy & Animal Science
Lina Hoerner-Schmid, Jelena Palic, Ralf S. Mueller, Bianka Schulz
Summary: The etiology of feline inflammatory bronchial disease is poorly understood. This study compared the degree of allergen-specific serum IgE responses between cats with different types of inflammatory bronchial disease and clinically healthy cats. The results showed that cats with mixed inflammation had significantly more positive reactions against mite allergens compared to healthy cats. Blood eosinophils were inversely correlated with the amount of allergen-specific serum IgE. Sensitization to dust mites seems to be more prevalent in cats with mixed inflammation. However, positive IgE reactions can be observed in both healthy and diseased cats, and should be interpreted in the context of clinical findings and environmental conditions.
Article
Immunology
Lenka Sukenikova, Viktor Cerny, Tomas Thon, Radka Roubalova, Zuzana Jiraskova Zakostelska, Olga Novotna, Petra Petraskova, Kristyna Borakova, Ingrid Kocourkova, Raja Lodinova-Zadnikova, Zdenek Musil, Libuse Kolarova, Ludmila Prokesova, Zdenek Valenta, Jiri Hrdy
Summary: Probiotic supplementation with Escherichia coli O83:K24:H31 (EcO83) in neonates of allergic mothers (AMs) was found to decrease allergy incidence and modulate immune markers, possibly through modulation of dendritic cell (DC) functional capacities. However, EcO83 supplementation had no significant impact on the microbiota composition in 10-year-old children.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Endocrinology & Metabolism
Seung Eun Lee, Ji Yeon Baek, Kyungdo Han, Eun Hee Koh
Summary: The study found that in premenopausal women, obesity and insulin resistance were positively correlated with elevated total IgE and atopy. However, no significant associations were found between metabolic status, obesity, and atopy in men and postmenopausal women.
DIABETES & METABOLISM JOURNAL
(2021)
Article
Allergy
Ioana Maris, Sabine Doelle-Bierke, Jean-Marie Renaudin, Lars Lange, Alice Koehli, Thomas Spindler, Jonathan Hourihane, Kathrin Scherer, Katja Nemat, C. Kemen, Irena Neustaedter, Christian Vogelberg, Thomas Reese, Ismail Yildiz, Zsolt Szepfalusi, Hagen Ott, Helen Straube, Nikolaos G. Papadopoulos, Susanne Haemmerling, Ute Staden, Michael Polz, Tihomir Mustakov, Ewa Cichocka-Jarosz, Renata Cocco, Alessandro Giovanni Fiocchi, Montserrat Fernandez-Rivas, Margitta Worm
Summary: The study showed that peanut allergy is a major cause of severe allergic reactions in European children, with characteristics such as asthma comorbidity and a higher rate of biphasic reactions. The use of intramuscular adrenaline as first-line treatment is low and needs improvement. The European Anaphylaxis Registry provides a valuable tool for continuous assessment of anaphylactic reactions.
Article
Biochemistry & Molecular Biology
Karla Rio-Aige, Ignasi Azagra-Boronat, Malen Massot-Cladera, Marta Selma-Royo, Anna Parra-Llorca, Sonia Gonzalez, Izaskun Garcia-Mantrana, Margarida Castell, Maria J. Rodriguez-Lagunas, Maria Carmen Collado, Francisco Jose Perez Cano
Summary: The study reveals that mothers pass natural passive immunity to their infants during gestation through the transplacental pathway, with differences in the plasma profile of immunoglobulins and cytokines between mothers and babies at birth. Additionally, maternal diet and microbiota composition have an impact on the levels and relationships of immune factors.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Health Care Sciences & Services
Nikolaos Pyrpyris, Maria Kritikou, Xenofon Aggelidis, Ioanna Manolaraki, Michael Makris, Nikolaos G. Papadopoulos, Paraskevi Xepapadaki
Summary: This study analyzes the characteristics of anaphylaxis in a pediatric cohort in Greece and finds a low rate of adrenaline autoinjector administration by lay people. However, drug prescription and counseling after the reaction could help improve correct acute anaphylaxis management in the future.
JOURNAL OF PERSONALIZED MEDICINE
(2022)