Article
Clinical Neurology
Volker A. Coenen, Bastian E. Sajonz, Peter C. Reinacher, Christoph P. Kaller, Horst Urbach, M. Reisert
Summary: The study evaluated the validity of displaying the dentato-rubro-thalamic tract (DRT) using diffusion weighted imaging (dMRI) in different tracking environments. The results show that FT2 and GT methods can depict DRTu with good quality, but the reconstruction of DRTx remains unreliable.
ACTA NEUROCHIRURGICA
(2021)
Article
Clinical Neurology
Nisha Giridharan, Kalman A. Katlowitz, Adrish Anand, Ron Gadot, Ricardo A. Najera, Ben Shofty, Rita Snyder, Christopher Larrinaga, Marc Prablek, Patrick J. Karas, Ashwin Viswanathan, Sameer A. Sheth
Summary: In this study, the accuracy of a streamlined robotic workflow for deep brain stimulation (DBS) lead implantation was compared with data from frame-based and frameless systems in the literature. The results showed that our workflow achieved comparable accuracy and reduced the chance for human errors and training difficulties.
OPERATIVE NEUROSURGERY
(2022)
Article
Clinical Neurology
Sandeep Kandregula, Caio M. Matias, Bhasakara Rao Malla, Michael R. Sperling, Chengyuan Wu, Aswhini D. Sharan
Summary: This study compared the accuracy of SEEG electrodes implanted in lateral versus supine position, finding better target accuracy in lateral position, especially in noninsular electrodes.
WORLD NEUROSURGERY
(2021)
Article
Computer Science, Artificial Intelligence
Andrea Spyrantis, Tirza Woebbecke, Daniel Ruess, Anne Constantinescu, Andreas Gierich, Klaus Luyken, Veerle Visser-Vandewalle, Eva Herrmann, Florian Gessler, Marcus Czabanka, Harald Treuer, Maximilian Ruge, Thomas M. Freiman
Summary: This study compared the mechanical accuracy of the Robotic Surgery Assistant (ROSA) and the Leksell stereotactic frame. The results showed that robotics was significantly more accurate. Procedural factors during surgery may have a more relevant impact on overall accuracy.
FRONTIERS IN NEUROROBOTICS
(2022)
Article
Infectious Diseases
Maria Fernanda Avila Mejia, Pei-Yun Shu, Dar-Der Ji
Summary: Dengue, Chikungunya, and Zika are co-endemic in Honduras and are often misdiagnosed due to similar clinical and epidemiological behavior. Only 30.84% of diagnostic accuracy was observed in physicians in primary care when comparing arboviral clinical diagnosis with RT-qPCR detection. Unspecific symptomatology, overlapping case definitions, and reported close contact to an arboviral patient might contribute to misdiagnosis.
BMC INFECTIOUS DISEASES
(2023)
Review
Clinical Neurology
Kai J. Miller, Anthony L. Fine
Summary: Surgery can cure or significantly improve seizures in patients with medication-refractory epilepsy. It requires a multidisciplinary team and new practices and technologies have expanded the scope of interventions.
Article
Clinical Neurology
Roberto Eleopra, Sara Rinaldo, Grazia Devigili, Massimo Mondani, Stanislao D'Auria, Nico Golfre Andreasi, Miran Skrap, Christian Lettieri
Summary: The study compared the clinical outcomes of two GPi-DBS surgical techniques for primary dystonia patients and found that the frameless technique is safe and well-tolerated, with similar effectiveness to the frame-based technique, without surgical complications.
FRONTIERS IN NEUROLOGY
(2021)
Review
Clinical Neurology
Vyshak Chandra, Justin D. Hilliard, Kelly D. Foote
Summary: This review article provides a historical perspective on the use of DBS for tremor, discusses various etiologies for tremor that can be managed effectively with DBS therapy, and reviews important aspects of DBS surgical technique, including recent technological advances. It is part of the Special Issue Tremor edited by Daniel D. Truong, Mark Hallett, and Aasef Shaikh.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
Ari Williams, Josue D. Ordaz, Hailey Budnick, Virendra R. Desai, Jignesh Tailor, Jeffrey S. Raskin
Summary: This study aimed to investigate the impact of time as a marker of cumulative stereotactic error during robot-assisted stereoelectroencephalography (sEEG). Results showed that there was no decremental accuracy over time, which may be attributed to the workflow prioritizing less error-prone trajectories. Further studies can explore the effect of training level on error rates.
OPERATIVE NEUROSURGERY
(2023)
Article
Neurosciences
Marco Prenassi, Linda Borellini, Tommaso Bocci, Elisa Scola, Sergio Barbieri, Alberto Priori, Roberta Ferrucci, Filippo Cogiamanian, Marco Locatelli, Paolo Rampini, Maurizio Vergari, Stefano Pastore, Bianca Datola, Sara Marceglia
Summary: The presence of post-surgery edema after deep brain stimulation implantation in Parkinson's disease patients is correlated with the quality of local field potential recordings, particularly with the localization of the edema.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Jan Roediger, Till A. Dembek, Gregor Wenzel, Konstantin Butenko, Andrea A. Kuehn, Andreas Horn
Summary: A data-driven model was developed to suggest optimal stimulation parameters for Parkinson's disease patients undergoing deep brain stimulation treatment, improving motor outcomes while minimizing the risk of side effects caused by stimulation. This approach may provide guidance for future DBS programming.
MOVEMENT DISORDERS
(2022)
Article
Clinical Neurology
Jahrane Dale, Stephen L. Schmidt, Kyle Mitchell, Dennis A. Turner, Warren M. Grill
Summary: This review describes the general features, mechanisms, technical recording factors, and clinical applications of brain evoked potentials (EPs) generated by deep brain stimulation (DBS) for Parkinson's disease (PD). DBS-evoked potentials arise from a complex integration of antidromic and orthodromic conduction pathway responses and provide valuable information for understanding the mechanisms and circuits involved in symptom treatment. These signals may serve as biomarkers for improving DBS outcomes and function. However, there are still critical gaps in our understanding of the mechanisms and clinical application of DBS-induced EPs.
Article
Clinical Neurology
Guillemette Clement, Thomas Wirth, Lucile Haumesser, Marie des Neiges Santin, Jimmy Voirin, Ouhaid Lagha-Boukbiza, Celine Labonne, Christine Tranchant, Nadine Longato, Clelie Phillipps, Mathieu Anheim
Summary: Language disorders are common in Parkinson's Disease patients after bilateral subthalamic Nucleus Deep Brain Stimulation (STN-DBS), with declines in phonemic and semantic verbal fluency observed. Other language domains remain stable. Localization outside the dorsolateral sensorimotor STN and high stimulation power may promote the decline in verbal fluency.
PARKINSONISM & RELATED DISORDERS
(2022)
Review
Geriatrics & Gerontology
Markey C. Olson, Holly Shill, Francisco Ponce, Sana Aslam
Summary: This systematic review aims to investigate the complications and risk of hospitalization following deep brain stimulation (DBS) surgery, and it is found that when candidates are carefully screened, DBS is a relatively low-risk procedure, but the hospitalization rate is somewhat increased for DBS patients. Further research is needed to determine the relative influence of more advanced disease vs. DBS itself in the increased rate of hospitalization.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Neurosciences
Constantin Pistol, Andrei Daneasa, Jean Ciurea, Alin Rasina, Andrei Barborica, Irina Oane, Ioana Mindruta
Summary: This study demonstrates the safety and accuracy of a frameless personalized 3D printed stereotactic implantation system for SEEG investigations in children under 4 years of age. Patient-customized stereotactic fixtures are shown to be a safe and accurate option for SEEG exploration in young children.
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY
(2021)
Article
Clinical Neurology
Jun-Pyo Hong, Hanim Kwon, Euyhyun Park, Sun-Uk Lee, Chan-Nyoung Lee, Byung-Jo Kim, Ji-Soo Kim, Kun-Woo Park
Summary: In patients with mild-to-moderate PD, vestibular function assessed by video head-impulse tests appears relatively preserved and has minimal impact on the risk of falls. Risk of postural instability is associated with the severity of clinical symptoms in PD.
PARKINSONISM & RELATED DISORDERS
(2024)
Article
Clinical Neurology
Yaqin Xiang, XiuRong Huang, Qian Xu, Zhenhua Liu, Yase Chen, Qiying Sun, Junling Wang, Hong Jiang, Lu Shen, Xinxiang Yan, Beisha Tang, Jifeng Guo
Summary: Using the novel data-driven method DEBM, this study determined the sequence of several common biomarker changes in Parkinson's disease (PD). The left putamen was found to be the earliest biomarker to become abnormal, followed by the right putamen, CSF alpha-synuclein, right caudate, left caudate, and serum NfL. The estimated disease stages showed significant differences between PD and healthy controls, and achieved a high accuracy for distinguishing PD from HC.
PARKINSONISM & RELATED DISORDERS
(2024)
Article
Clinical Neurology
Yan Li, David J. McLernon, Carl E. Counsell, Angus D. Macleod
Summary: This study aimed to investigate the incidence and risk factors for institutionalisation in Parkinson's disease (PD) and atypical parkinsonism (AP). The study found that institutionalisation was more frequent in AP compared to PD and controls. Age, poorer cognition, and more-severe parkinsonian impairment were independent predictors of institutionalisation.
PARKINSONISM & RELATED DISORDERS
(2024)
