Article
Multidisciplinary Sciences
Shuai Yan, Dong Wang, Junrui Zhang, Xiaojin Mo, Yu Feng, Liling Duan, Deyu Liu, Fan Li, Yongchun Dao, Ting Zhang, Wei Hu, Zheng Feng, Bin Zheng
Summary: The study in east Gansu province of China found that the prevalence of echinococcosis is associated with gender, age, and education level. The cross-sectional survey and prevalence surveillance both showed fluctuating rates of infection over different years.
SCIENTIFIC REPORTS
(2021)
Article
Medical Informatics
Yongfeng Yang, Yangdan Cairang, Tian'an Jiang, Jianhua Zhou, Li Zhang, Baowen Qi, Shumei Ma, Lina Tang, Dong Xu, Lingdai Bu, Rui Bu, Xiang Jing, Hui Wang, Zubang Zhou, Cheng Zhao, Baoming Luo, Liwen Liu, Jianqin Guo, Yuzhen Nima, Guoyong Hua, Zengcheng Wa, Yuying Zhang, Guoyi Zhou, Wen Jiang, Changcheng Wang, Yang De, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Fangyi Liu, Jianping Dou, Hui Feng, Chong Wu, Ruifang Wang, Jie Hu, Qi Yang, Yanchun Luo, Jiapeng Wu, Haining Fan, Ping Liang, Jie Yu
Summary: This study aimed to develop a deep convolutional neural network (DCNN) model based on ultrasonography to identify and classify liver lesions, including echinococcosis. The results showed that the DCNN model demonstrated high accuracy and robustness in diagnosing echinococcosis and its types.
LANCET DIGITAL HEALTH
(2023)
Article
Immunology
Hui Wang, Chuan-Shan Zhang, Bin-Bin Fang, Jiao Hou, Wen-Ding Li, Zhi-De Li, Liang Li, Xiao-Juan Bi, Liang Li, Abuduaini Abulizi, Ying-Mei Shao, Ren-Yong Lin, Hao Wen
Summary: The study reveals that M2 macrophages dominate in hepatic macrophages associated with E. multilocularis infection. Macrophages in the liver tend to polarize towards the M1 phenotype at the early stage of infection, then shift to the M2 phenotype.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Microbiology
Magdalena Stefaniak, Monika Derda, Pawel Zmora, Szymon Pawel Nowak
Summary: This study aimed to assess the risk factors of E. multilocularis infections and describe the clinical course of AE in 36 patients. Results showed that most patients were involved in farming, livestock breeding, forest work, or animal shelters. The majority of patients were diagnosed with E. multilocularis infection within 6 months using imaging and immunoassay techniques. All hospitalized patients initiated anti-parasitic therapy upon diagnosis. The study concludes that regular abdominal imaging examinations and detection of specific antibodies are recommended for individuals at risk, and regular screening tests in hyperendemic areas would improve early detection and clinical prognosis of this life-threatening parasitic disease.
Article
Microbiology
Deping Cao, Mingquan Pang, Defang Wu, Gen Chen, Xiaohong Peng, Kai Xu, Haining Fan
Summary: This study analyzed the gut microbiome composition of patients with alveolar echinococcosis (AE) and cystic echinococcosis (CE), and identified differences in the fecal bacteria between the patients and healthy individuals. The findings contribute to our understanding of the gut microbiome composition of AE and CE patients.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xu Deng, Jing-jing Wang, Zhi-xin Wang, Hai-ning Fan, Hai-jiu Wang, Han-sheng Huang, Kai-qaing Wang, Xiao-zhou Yang, Jun-wei Han, Yangdan Cairang
Summary: This study evaluated the efficacy and safety of microwave ablation (MWA) in the treatment of hepatic alveolar echinococcosis (HAE). The results showed that MWA achieved a complete ablation rate of 100% with a recurrence rate of 13%. There were significant changes in certain laboratory indicators after MWA treatment. The study indicates that MWA may be a safe and effective treatment option for HAE.
BMC MEDICAL IMAGING
(2022)
Article
Parasitology
Ying Ke, Xiaojuan Bi, Ning Yang, Jin Chu, Xiaohong Li, Wenmei Ma, Hui Liu, Hui Wang, Liang Li, Cheng Li, Yongde Qin, Tuerganaili Aji, Yingmei Shao, Guodong Lu, Renyong Lin
Summary: PDGF-BB can serve as a simple, non-invasive, and quick biomarker to assess the metabolic activity of lesions in AE patients. It is significantly negatively correlated with metabolically active AE and positively correlated with metabolic activity, PNM stage, and lesion size.
Article
Parasitology
Xuhui Zhang, Lamu Suolang, Yelei Ren, Yifei Wang, Yong Jiang, Xiaofei Zhong, Zehui Gou, Wu Zhou, Juan Chen, Yongzhong Li, Diming Cai
Summary: In this study, contrast-enhanced ultrasound (CEUS) was found to be more accurate than conventional ultrasound (US) in differentiating between cystic echinococcosis (CE) and alveolar echinococcosis (AE) in the liver. The accuracy rate for CEUS was 91.3%, while for US it was 65.2%. Therefore, CEUS can be considered a reliable tool for the differentiation of hepatic echinococcosis.
PARASITES & VECTORS
(2023)
Article
Parasitology
Tian Ma, Qian Wang, Mengmeng Hao, Chuizhao Xue, Xu Wang, Shuai Han, Qian Wang, Jiangshan Zhao, Xiao Ma, Xianglin Wu, Xiaofeng Jiang, Lei Cao, Yaming Yang, Yu Feng, Quzhen Gongsang, Juergen Scheffran, Liqun Fang, Richard James Maude, Canjun Zheng, Fangyu Ding, Weiping Wu, Dong Jiang
Summary: This study used the national echinococcosis survey data from 2012 to 2016 to investigate the spatial prevalence, demographic characteristics, and risk factors of cystic and alveolar echinococcosis in China. The results showed that female gender, older age, occupation as a herdsman or religious worker, and illiteracy were identified as risk factors for both types of echinococcosis. The prevalence of the diseases varied geographically, with high endemicity observed in the Tibetan Plateau region. Various environmental, biological, and social factors were found to be associated with the diseases. The findings will contribute to the development of targeted prevention measures and disease control strategies.
PARASITES & VECTORS
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Paul Calame, Mathieu Weck, Andreas Busse-Cote, Eleonore Brumpt, Carine Richou, Celia Turco, Alexandre Doussot, Solange Bresson-Hadni, Eric Delabrousse
Summary: Echinococcosis is a parasitic disease caused by two different tapeworms, and can be classified into two forms. Although their imaging findings differ, they share similarities in management and treatment. Interventional procedures, along with medical treatment and surgery, offer new therapeutic options. Radiologists play a crucial role in multidisciplinary consultation meetings for hepatic echinococcosis, evaluating parasite activity and guiding appropriate therapy choices. This review highlights the importance of radiologists possessing core knowledge to actively participate in these meetings.
INSIGHTS INTO IMAGING
(2022)
Article
Public, Environmental & Occupational Health
A. Jide, Jingni Zhang, Jinping Chai, Shunyun Zhao, Hao Wang, A. Xiangren, Jinyu Yang
Summary: This study compared the efficacy of anatomic and non-anatomic hepatectomy for the treatment of hepatic alveolar echinococcosis (AE). The results showed that anatomic hepatectomy was superior to non-anatomic hepatectomy in terms of intraoperative blood loss, blood transfusion, and porta hepatis occlusion time. There were also significant differences between the two groups in postoperative liver function, surgical complications, and AE recurrence. Anatomic hepatectomy was not only safe for AE but also showed better short-term and long-term superiority than non-anatomic hepatectomy.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Microbiology
Mehdi Borhani, Saeid Fathi, Enayat Darabi, Fatemeh Jalousian, Sami Simsek, Haroon Ahmed, Harun Kaya Kesik, Seyed Hossein Hosseini, Thomas Romig, Majid Fasihi Harandi, Iraj Mobedi
Summary: Echinococcosis, a neglected zoonosis, is endemic in Tibetan, Pamir, and Iranian plateaus. Pakistan, Turkey, and Iran have high endemicity of echinococcosis and share strong cultural and socioeconomic ties. Effective control programs require multi/intersectoral coordination within a One Health approach and enhanced international collaboration.
CLINICAL MICROBIOLOGY REVIEWS
(2021)
Review
Infectious Diseases
Xiao-Kun Yu, Le Zhang, Wen-Jun Ma, Wen-Zhong Bi, Sheng-Gang Ju
Summary: Hepatic echinococcosis is a parasitic infectious disease with a high incidence in pastoral areas, affecting the quality of life for people living in those regions. This study focuses on the radiological characteristics of hepatic echinococcosis, aiming to assist doctors in accurately diagnosing and further investigating the disease.
INFECTION AND DRUG RESISTANCE
(2021)
Article
Microbiology
Mecit Kantarci, Sonay Aydin, Suat Eren, Hayri Ogul, Okan Akhan
Summary: This study retrospectively evaluated the US, CT, and MRI images of 61 patients with liver AE and defined the major imaging findings. The types and subtypes of lesions varied according to different classification methods. These findings may assist radiologists in accurately and timely diagnosing liver AE.
Article
Parasitology
Tatsuro Hifumi, Kohei Akioka, Tetsuya Tanaka, Noriaki Miyoshi
Summary: The developed LAMP assay in this study showed high sensitivity and specificity for the diagnosis of alveolar echinococcosis in horses, which is equivalent to conventional PCR testing and can be used as an alternative for routine genetic diagnosis.
VETERINARY PARASITOLOGY
(2021)
