Journal
PARASITOLOGY INTERNATIONAL
Volume 61, Issue 1, Pages 10-16Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.parint.2011.08.014
Keywords
Opisthorchis viverrini; Clonorchis sinensis; Prevalence; Lower Mekong Basin; Current statatus
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Funding
- International Development and Research Centre (IDRC)
- Office of the Higher Education Commission, through the Health Cluster (SHeP-GMS), Khon Kaen University
- National Institutes of Health, USA [UO1-AI065871, R01CA155297]
- Faculty of Medicine, Resident International Professor Program
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This review highlights the current status and control of liver fluke infections in the Mekong Basin countries where Opisthorchis and Clonorchis are highly endemic. Updated data on prevalence and distribution have been summarized from presentations in the 96 Years of Opisthorchiasis. International Congress of Liver Flukes. It is disturbing that despite treatment and control programs have been in place for decades, all countries of the Lower Mekong Basin are still highly endemic with O. viverrini and/or C. sinensis as well as alarmingly high levels of CCA incidence. A common pattern that is emerging in each country is the difference in transmission of O. viverrini between lowlands which have high prevalence versus highlands which have low prevalence. This seems to be associated with wetlands, flooding patterns and human movement and settlement. A more concerted effort from all community, educational, public health and government sectors is necessary to successfully combat this fatal liver disease of the poor. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
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