Increased susceptibility of a triclabendazole (TCBZ)-resistant isolate of Fasciola hepatica to TCBZ following co-incubation in vitro with the P-glycoprotein inhibitor, R(+)-verapamil

An amino acid substitution in Fasciola hepatica P-glycoprotein from triclabendazole-resistant and triclabendazole-susceptible populations

(2012) Richard Wilkinson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate

(2012) D.J. Bartley et al.   VETERINARY PARASITOLOGY

The role of several ABC transporter genes in ivermectin resistance in Caenorhabditis elegans

(2012) Ruofeng Yan et al.   VETERINARY PARASITOLOGY

Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin

(2012) Bernadette F. Ardelli et al.   VETERINARY PARASITOLOGY

ABC transporters influence sensitivity of Brugia malayi to moxidectin and have potential roles in drug resistance

(2011) L.E. Stitt et al.   EXPERIMENTAL PARASITOLOGY

Pharmacology and potential physiological significance of schistosome multidrug resistance transporters

(2011) Ravi S. Kasinathan et al.   EXPERIMENTAL PARASITOLOGY

Cytochrome P450 in fluke Opisthorchis felineus: Identification and characterization

(2011) Maria Y. Pakharukova et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica

(2011) C. Devine et al.   PARASITOLOGY RESEARCH

Erratum to: Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica

(2011) C. Devine et al.   PARASITOLOGY RESEARCH

The role of Brugia malayi ATP-binding cassette (ABC) transporters in potentiating drug sensitivity

(2011) Jeffrey B. Tompkins et al.   PARASITOLOGY RESEARCH

Reducing the future threat from (liver) fluke: realistic prospect or quixotic fantasy?

(2011) Ian Fairweather   VETERINARY PARASITOLOGY

Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole

(2011) C. Devine et al.   VETERINARY PARASITOLOGY

Raising the bar on reporting 'triclabendazole resistance'

(2011) I. Fairweather   VETERINARY RECORD

Genetic Knockdown and Pharmacological Inhibition of Parasite Multidrug Resistance Transporters Disrupts Egg Production in Schistosoma mansoni

(2011) Ravi S. Kasinathan et al.   PLoS Neglected Tropical Diseases

P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance

(2011) Anne Lespine et al.   International Journal for Parasitology-Drugs and Drug Resistance

Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells

(2010) Jacques Dupuy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cattle nematodes resistant to macrocyclic lactones: Comparative effects of P-glycoprotein modulation on the efficacy and disposition kinetics of ivermectin and moxidectin

(2010) A. Lifschitz et al.   EXPERIMENTAL PARASITOLOGY

Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel

(2010) Ravi S. Kasinathan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Piperonyl butoxide enhances triclabendazole action against triclabendazole-resistant Fasciola hepatica

(2010) C. DEVINE et al.   PARASITOLOGY

Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole

(2010) Catherine Devine et al.   PARASITOLOGY RESEARCH

Potentiation of triclabendazole sulphoxide-induced tegumental disruption by methimazole in a triclabendazole-resistant isolate of Fasciola hepatica

(2010) Catherine Devine et al.   PARASITOLOGY RESEARCH

Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep

(2010) A. Lifschitz et al.   VETERINARY PARASITOLOGY

Enhancement of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica by co-treatment with ketoconazole

(2010) C. Devine et al.   VETERINARY PARASITOLOGY

Liver fluke isolates: a question of provenance

(2010) I. Fairweather   VETERINARY PARASITOLOGY

In vitrooxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxideex vivo

(2010) Hana Bártíková et al.   XENOBIOTICA

A Review of the Pharmacological Interactions of Ivermectin in Several Animal Species

(2009) Aranzazu Gonzalez-Canga et al.   CURRENT DRUG METABOLISM

Interaction of Macrocyclic Lactones with the Multidrug Transporters: The Bases of the Pharmacokinetics of Lipid-Like Drugs

(2009) A. Lespine et al.   CURRENT DRUG METABOLISM

Xenobiotic metabolizing enzymes and metabolism of anthelminthics in helminths

(2009) Viktor Cvilink et al.   DRUG METABOLISM REVIEWS

Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel

(2009) Ravi S. Kasinathan et al.   FASEB JOURNAL

Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility

(2009) Shanta M. Messerli et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A scanning electron microscope study on the route of entry of triclabendazole into the liver fluke, Fasciola hepatica

(2009) E. TONER et al.   PARASITOLOGY

Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica

(2009) L. HALFERTY et al.   PARASITOLOGY

A transmission electron microscope study on the route of entry of triclabendazole into the liver fluke, Fasciola hepatica

(2009) E. TONER et al.   PARASITOLOGY

Inhibition of cytochrome P450-mediated metabolism enhances ex vivo susceptibility of Fasciola hepatica to triclabendazole

(2009) C. DEVINE et al.   PARASITOLOGY

P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus

(2009) D. J. BARTLEY et al.   PARASITOLOGY

Surface changes in adult Fasciola hepatica following treatment in vivo with the experimental fasciolicide, compound alpha

(2009) M. McConville et al.   PARASITOLOGY RESEARCH

An update on P-glycoprotein and drug resistance in Schistosoma mansoni

(2009) Catherine E. James et al.   TRENDS IN PARASITOLOGY

Inhibition and induction of human cytochrome P450 enzymes: current status

(2008) Olavi Pelkonen et al.   ARCHIVES OF TOXICOLOGY

Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans

(2008) Catherine E. James et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep

(2008) G. VIRKEL et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Fasciola hepatica expresses multiple α- and β-tubulin isotypes

(2008) Louise A. Ryan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Expression of ATP-binding cassette multidrug transporters in the giant liver fluke Fasciola gigantica and their possible involvement in the transport of bile salts and anthelmintics

(2008) Supeecha Kumkate et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Effect of the metabolic inhibitor, methimazole on the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica

(2008) C. DEVINE et al.   PARASITOLOGY

Phase I biotransformation of albendazole in lancet fluke (Dicrocoelium dendriticum)

(2008) V. Cvilink et al.   RESEARCH IN VETERINARY SCIENCE

ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics

(2008) Anne Lespine et al.   TRENDS IN PARASITOLOGY

Ketoconazole increases the plasma levels of ivermectin in sheep

(2008) Michel Alvinerie et al.   VETERINARY PARASITOLOGY

Albendazole enantiomeric metabolism and binding to cytosolic proteins in the liver fluke Fasciola hepatica

(2008) H. Solana et al.   VETERINARY RESEARCH COMMUNICATIONS