Article
Medicine, General & Internal
Carlo Bienkowski, Malgorzata Aniszewska, Monika Kowalczyk, Jolanta Popielska, Konrad Zawadka, Agnieszka Oldakowska, Maria Pokorska-Spiewak
Summary: This study aimed to evaluate the risk factors associated with Toxoplasma gondii infection in pregnant women. The results showed that living in rural areas and eating raw meat were independent risk factors for T. gondii infection during pregnancy.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Lokman Galal, Frederic Ariey, Meriadeg Ar Gouilh, Marie-Laure Darde, Azra Hamidovic, Franck Letourneur, Franck Prugnolle, Aurelien Mercier
Summary: This study analyzes 156 genomes of Toxoplasma gondii and provides estimates of the parasite's mutation rate and generation time. It reveals that a specific haplotype is associated with the spread of the parasite through cats, indicating its role in sexual reproduction.
NATURE COMMUNICATIONS
(2022)
Article
Veterinary Sciences
Ningbo Xia, Nuo Ji, Longjiao Li, Yuan Huang, Congshan Yang, Xuefang Guo, Qinghong Guo, Bang Shen, Lihua Xiao, Yaoyu Feng
Summary: This study investigated the seroprevalence and risk factors of T. gondii infection in cats across China. The study found higher infection rates in Sichuan, Chongqing, and Hunan, and reported the seroprevalence in Qinghai, Anhui, Jiangxi, Shaanxi, and Ningxia for the first time. Age and lifestyle (stray or pet) of cats were identified as risk factors for T. gondii infection.
BMC VETERINARY RESEARCH
(2022)
Article
Multidisciplinary Sciences
Iti Saraav, Luisa Cervantes-Barragan, Philipp Olias, Yong Fu, Qiuling Wang, Leran Wang, Yi Wang, Matthias Mack, Megan T. Baldridge, Thaddeus Stappenbeck, Marco Colonna, L. David Sibley
Summary: Oral infection with Toxoplasma gondii exacerbates damage to the colon caused by chemical irritant and impairs wound healing by suppressing stem cell regeneration. Enhanced tissue damage is due to inflammatory monocytes releasing inflammatory mediators.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Microbiology
Idessania Nazareth Costa, Mayara Ribeiro, Priscila Silva Franco, Rafaela Jose da Silva, Thadia Evelyn de Araujo, Iliana Claudia Balga Milian, Luana Carvalho Luz, Pamela Mendonca Guirelli, Gerson Nakazato, Jose Roberto Mineo, Tiago W. P. Mineo, Bellisa Freitas Barbosa, Eloisa Amalia Vieira Ferro
Summary: The study revealed that AgNp-Bio can reduce T. gondii infection in trophoblast cells and villous explants, while also increasing the production of inflammatory mediators in the cells.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Heloise Debare, Nathalie Moire, Firmin Baron, Louis Lantier, Bruno Heraut, Nathalie Van Langendonck, Caroline Denevault-Sabourin, Isabelle Dimier-Poisson, Francoise Debierre-Grockiego
Summary: SP230, a specific inhibitor of TgCDPK1, showed significant efficacy in reducing parasite burdens in both dams and foetuses in a mouse model of congenital toxoplasmosis, making it a promising candidate for alternative therapeutics for infected pregnant women.
Review
Food Science & Technology
Pablo-Jesus Marin-Garcia, Nuria Planas, Lola Llobat
Summary: This article reviews the detection methods, prevalence, and control measures of Toxoplasma gondii in the food industry. T. gondii is a common parasite that causes infection through food contamination, but standardized detection methods are currently lacking in the industry. The main detection methods include bioassays, cell culture, molecular and microscopic techniques, and serological methods. Due to the high prevalence of T. gondii in many food products, standardized detection methods and control measures are necessary.
Article
Immunology
Mohammad Mahdi Jafari, Zahra Azimzadeh Tabrizi, Mohammad Saaid Dayer, Nazanin Atieh Kazemi-Sefat, Mahshid Mohtashamifard, Rahimeh Mohseni, Atefeh Bagheri, Saeed Bahadory, Amir Karimipour-Saryazdi, Fatemeh Ghaffarifar
Summary: Toxoplasma gondii infection is associated with immune response, which can be used as prognosis markers. Immunotherapy has become a new approach for toxoplasmosis treatment.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Article
Microbiology
Rina Ikeda, Nanako Ushio, Ahmed M. Abdou, Hidefumi Furuoka, Yoshifumi Nishikawa
Summary: The study found that TLR2(-/-) mice are less susceptible to abnormal pregnancy induced by Toxoplasma gondii infection compared to wild-type mice. While there were no significant differences in parasite numbers and histological changes between the two groups, the expression of certain cytokines in the placentas of infected wild-type mice was affected by T. gondii infection, while TLR2(-/-) mice showed no such changes. Serum interferon-gamma levels were significantly lower in infected TLR2(-/-) mice, indicating a potential role of TLR2 signaling in immune response and placental function during late pregnancy.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Samuel Cota Teixeira, Marina Paschoalino, Guilherme de Souza, Alessandra Monteiro Rosini, Joed Pires de Lima Junior, Luana Carvalho Luz, Aryani Felixa Fajardo Martinez, Rosiane Nascimento Alves, Marcos Paulo Oliveira Almeida, Jaqueline Lopes Damasceno, Francesca Ietta, Bellisa Freitas Barbosa, Eloisa Amalia Vieira Ferro, Carlos Henrique Gomes Martins
Summary: This study found that the natural polyphenol Rottlerin has anti-parasitic activity against Toxoplasma gondii infection. Rottlerin impairs the infection and proliferation of the parasite in human trophoblastic cells and villous explants. Its mode of action includes direct effects on the parasite and modulation of host cell components, offering a promising tool for preventing and/or treating congenital toxoplasmosis.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Parasitology
Jiaofeng Huang, Jiaolong Zheng, Bang Liu, Lingling Lu, Haicong Wu, Su Lin, Dongliang Li
Summary: This study found that Toxoplasma gondii infection is associated with higher mortality in the general population, and this association is related to age and sex. This suggests that Toxoplasma gondii infection may be an important public health issue.
PARASITES & VECTORS
(2022)
Article
Immunology
Guilherme de Souza, Samuel Cota Teixeira, Aryani Felixa Fajardo Martinez, Rafaela Jose Silva, Luana Carvalho Luz, Joed Pires de Lima Junior, Alessandra Monteiro Rosini, Natalia Carine Lima dos Santos, Rafael Martins de Oliveira, Marina Paschoalino, Matheus Carvalho Barbosa, Rosiane Nascimento Alves, Angelica Oliveira Gomes, Claudio Vieira da Silva, Eloisa Amalia Vieira Ferro, Bellisa Freitas Barbosa
Summary: In this study, the impact of T. cruzi and recombinant P21 on T. gondii infection was investigated in BeWo cells and human placental explants. The results showed that T. cruzi infection and rP21 can increase the invasion and decrease the intracellular proliferation of T. gondii in BeWo cells. In human placental villi, rP21 can either increase or decrease T. gondii proliferation, while T. cruzi infection increases T. gondii proliferation. These findings highlight the importance of neonatal screening for both diseases and suggest P21 as a potential therapeutic target for Chagas disease.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Syrian G. Sanchez, Emilie Bassot, Aude Cerutti, Hoa Mai Nguyen, Amel Aida, Nicolas Blanchard, Sebastien Besteiro
Summary: Toxoplasma gondii is responsible for toxoplasmosis, a disease that can be serious when contracted during pregnancy, but can also be a threat for immunocompromised individuals. The study finds that targeting the apicoplast in bradyzoites, the latent form of the parasite, leads to a loss of long-term viability, suggesting the apicoplast as a potential therapeutic target.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Multidisciplinary Sciences
Arwa Lachkhem, Lokman Galal, Ibtissem Lahmar, Karine Passebosc, Homayoun Riahi, Nicolas Plault, Marie-Laure Darde, Aurelien Mercier, Hamouda Babba
Summary: Isolation and genetic characterization of Toxoplasma gondii strains from domestic animals in Southern and coastal area of Tunisia revealed a large predominance of type II strains, followed by type III, and for the first time in Tunisia, an isolate of Africa 4 lineage. Analyses of population genetics also showed the presence of a divergent population of type II lineage in Tunisia, supporting limited recent migrations of strains between Tunisia and other countries.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Jorge Enrique Gomez-Marin, Juliana Munoz-Ortiz, Manuela Mejia-Oquendo, Jose Y. Arteaga-Rivera, Nicolas Rivera-Valdivia, Maria Cristina Boh, Stefany Velasco-Velasquez, Gabriela Castano-de-la-Torre, John Alejandro Acosta-Davila, Laura Lorena Garcia-Lopez, Elizabeth Torres-Morales, Monica Vargas, Juan David Valencia, Daniel Celis-Giraldo, Alejandra De-la-Torre
Summary: This study aimed to determine the frequency of retinochoroidal lesions caused by ocular toxoplasmosis and their relationships with risk factors in Armenia-Quindio, Colombia. The results showed that 10.5% of individuals had retinochoroidal scars suggestive of old inactive Toxoplasma gondii infection, and consumption of bottled water was found to be protective against T. gondii infection.
Article
Pediatrics
Jorge Enrique Gomez-Marin, Angela Liliana Londono, Nancy Cabeza-Acevedo, Elizabeth Torres, Leonidas Navarrete-Moncada, Oriana Bueno, Alejandro Nati, Pedro Nieto-Rodriguez, Stiven Ariza-Pardo, Karol Johana Isaza, Valeria Chacon-Alvarez, Stefany Andrea Romero-Delgado, Saray Grijalva-Plaza
Summary: This study reports the diagnosis, treatment, and evolution of ocular toxocariasis cases in a specialized consultation in Quindio, Colombia. No cases were observed between 2000 and 2017, but there was a rise in confirmed cases from November 2017 to March 2019, particularly among children under 15 years old. Epidemiological studies are necessary to establish the reasons for the increase in cases in this region.
JOURNAL OF TROPICAL PEDIATRICS
(2021)
Editorial Material
Immunology
Jorge Enrique Gomez-Marin, Alejandra de-la-Torre
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Parasitology
Deicy Munoz-Sanchez, Jessica Trivino-Valencia, Fabiana Lora-Suarez, Jorge Enrique Gomez-Marin
Summary: This study found that gastrointestinal symptoms in Colombian individuals with Blastocystis infection depend on the infecting subtype, with Subtype 2 showing a higher prevalence in symptomatic individuals. In vitro culture also revealed that Subtype 2 isolates had fewer total cells with dominant growth of vacuolar forms compared to Subtypes 1 and 3.
ACTA PARASITOLOGICA
(2021)
Article
Parasitology
Diego A. Molina, Gerardo A. Ramos, Alejandro Zamora-Velez, Gina M. Gallego-Lopez, Cristian Rocha-Roa, Jorge Enrique Gomez-Marin, Edwar Cortes
Summary: Current treatments for toxoplasmosis have shown side effects, prompting the search for new therapeutic agents. The synthesis of novel 2-hydrazono-4-thiazolidinones derivatives demonstrated potent growth inhibition against T. gondii, suggesting potential anti-parasitic drug properties. The combination of appropriate detection technologies, combinatorial chemistry, and computational biology appears to be an effective strategy for efficient drug discovery.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
(2021)
Article
Biotechnology & Applied Microbiology
Marynes Quintero, Lina M. Blandon, Oscar M. Vidal, Juan D. Guzman, Jorge E. Gomez-Marin, Albert D. Patino, Diego A. Molina, Gloria M. Puerto-Castro, Javier Gomez-Leon
Summary: This study evaluated the biological activity of extracts from marine bacteria cultures against Toxoplasma gondii and Mycobacterium tuberculosis. The Bacillus sp. INV FIR48 extract showed anti-T. gondii and anti-tuberculosis biological activity with low cytotoxicity, and peptide metabolites were detected in the extract. Marine bacteria are promising sources of natural products for anti-infective purposes, especially against prevalent diseases like toxoplasmosis and tuberculosis.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Infectious Diseases
Maria Ines Plazas, Jacqueline Salamanca-Marin, Elizabeth Torres-Morales, Juan Camilo Londono, Daniel Celis-Giraldo, Jorge Enrique Gomez-Marin
Summary: Interpretation of IgM anti-Toxoplasma can be problematic due to the presence of natural IgM. This study analyzed 1,503 sera and established natural and false-positive results. The concordance between ELISA and two semi-automatized systems was calculated, and it was found that ELISA had poor concordance. Automated assays are recommended for measuring IgM anti-Toxoplasma.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2022)
Article
Parasitology
Juan D. Valencia-Hernandez, John Alejandro Acosta-Davila, Juan Camilo Arenas-Garcia, Laura Lorena Garcia-Lopez, Diego Alejandro Molina-Lara, Ailan Farid Arenas-Soto, Diego A. Eraso-Ortiz, Jorge E. Gomez-Marin
Summary: This study developed a machine learning software called ApiPredictor UniQE V2.0 to predict adhesins proteins in Toxoplasma gondii. Using this software, a new adhesin protein called TgSRS12B was identified and its interaction with the membrane fractions of human cells was confirmed.
EXPERIMENTAL PARASITOLOGY
(2022)
Article
Microbiology
Shishir Singh, Mateo Murillo-Leon, Niklas Sebastian Endres, Ailan Farid Arenas Soto, Jorge Enrique Gomez-Marin, Florence Melbert, Thirumala-Devi Kanneganti, Masahiro Yamamoto, Claudia Campos, Jonathan Charles Howard, Gregory Alan Taylor, Tobias Steinfeldt
Summary: Toxoplasmosis is a common parasitic zoonosis caused by Toxoplasma gondii, which infects virtually all warm-blooded animals including humans. This study identifies a virulence effector, ROP39, in T. gondii that specifically targets Irgb10 to evade IRG-mediated control, increasing its pathogenicity. This finding contributes to our understanding of the coevolutionary relationship between T. gondii and mice, which are important for transmission.
Article
Psychiatry
Jennifer Nessim, Julio Cesar Luna-Ramirez, German Alberto Moreno-Gomez, Diana Milena Galvis-Soto, Jorge E. Gomez-Marin
Summary: There is strong evidence from meta-analysis indicating a relationship between toxoplasmosis and various psychiatric diseases including schizophrenia, bipolar disorder, and suicidal behavior. This study estimates the number of cases by assessing the attributable fraction of these diseases due to toxoplasmosis. The population attributable fraction for mental diseases associated with toxoplasmosis is 20.4% for schizophrenia, 27.3% for bipolar disorder, and 0.29% for suicidal behavior. The estimated number of individuals with mental diseases associated with toxoplasmosis ranges from 4,816,491 to 5,564,407 for schizophrenia, 6,348,946 to 7,510,118.82 for bipolar disorder, and 24,310 to 28,151 for self-harm. Globally, the lower estimated number is 11,189,748 and the upper estimated number is 13,102,678 for the year 2019. Geographic variations in the importance of risk factors for toxoplasmosis associated with mental diseases are observed, with water contamination being the most important risk factor in Africa and cooking conditions of meats being important in the European region. Given the potential impact of reducing this parasite on the general population, toxoplasmosis and mental health should be a research priority.
PSYCHIATRY RESEARCH
(2023)
Article
Pediatrics
Mariangela Soberon Felin, Kanix Wang, Aliya Moreira, Andrew Grose, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpetua Goodall, Morgan Michalowski, Mahmoud Ismail, Monica Christmas, Stephen Schrantz, Zuleima Caballero, Ximena Norero, Dora Estripeaut, David Ellis, Catalina Raggi, Catherine Castro, Claudia Rengifo-Herrera, Davina Moossazadeh, Margarita Ramirez, Abhinav Pandey, Kevin Ashi, Samantha Dovgin, Ashtyn Dixon, Xuan Li, Ian Begeman, Sharon Heichman, Joseph Lykins, Delba Villalobos-Cerrud, Lorena Fabrega, Jose Luis Sanchez Montalvo, Connie Mendivil, Mario R. Quijada, Silvia Fernandez-Pirla, Valli de La Guardia, Digna Wong, Mayrene Ladron de Guevara, Carlos Flores, Jovanna Borace, Anabel Garcia, Natividad Caballero, Maria Theresa Moreno de Saez, Michael Politis, Stephanie Ross, Mimansa Dogra, Vishan Dhamsania, Nicholas Graves, Marci Kirchberg, Kopal Mathur, Ashley Aue, Carlos M. Restrepo, Alejandro Llanes, German Guzman, Arturo Rebellon, Kenneth Boyer, Peter Heydemann, A. Gwendolyn Noble, Charles Swisher, Peter Rabiah, Shawn Withers, Teri Hull, David Frim, David McLone, Chunlei Su, Michael Blair, Paul Latkany, Ernest Mui, Daniel Vitor Vasconcelos-Santos, Alcibiades Villareal, Ambar Perez, Carlos Andres Naranjo Galvis, Monica Vargas Montes, Nestor Ivan Cardona Perez, Morgan Ramirez, Cy Chittenden, Edward Wang, Laura Lorena Garcia-Lopez, Juliana Munoz-Ortiz, Nicolas Rivera-Valdivia, Maria Cristina Bohorquez-Granados, Gabriela Castano de-la-Torre, Guillermo Padrieu, Juan David Valencia Hernandez, Daniel Celis-Giraldo, John Alejandro Acosta Davila, Elizabeth Torres, Manuela Mejia Oquendo, Jose Y. Arteaga-Rivera, Dan L. Nicolae, Andrey Rzhetsky, Nancy Roizen, Eileen Stillwaggon, Larry Sawers, Francois Peyron, Martine Wallon, Emanuelle Chapey, Pauline Levigne, Carmen Charter, Migdalia De Frias, Jose Montoya, Cindy Press, Raymund Ramirez, Despina Contopoulos-Ioannidis, Yvonne Maldonado, Oliver Liesenfeld, Carlos Gomez, Kelsey Wheeler, Samantha Zehar, James McAuley, Denis Limonne, Sandrine Houze, Sylvie Abraham, Raphael Piarroux, Vera Tesic, Kathleen Beavis, Ana Abeleda, Mari Sautter, Bouchra El Mansouri, Adlaoui El Bachir, Fatima Amarir, Kamal El Bissati, Ellen Holfels, Richard Penn, William Cohen, Alejandra de-la-Torre, Gabrielle Britton, Jorge Motta, Eduardo Ortega-Barria, Isabel Luz Romero, Paul Meier, Michael Grigg, Jorge Gomez-Marin, Jagannatha Rao Kosagisharaf, Xavier Saez Llorens, Osvaldo Reyes, Rima McLeod
Summary: This review examines the creation and evaluation of educational materials to reduce the disease burden of Toxoplasma infections, emphasizing the need for robust longitudinal studies and region-specific modifications of educational materials.
CURRENT PEDIATRICS REPORTS
(2022)
Article
Pediatrics
Mariangela Soberon Felin, Kanix Wang, Catalina Raggi, Aliya Moreira, Abhinav Pandey, Andrew Grose, Zuleima Caballero, Claudia Rengifo-Herrera, Margarita Ramirez, Davina Moossazadeh, Catherine Castro, Jose Luis Sanchez Montalvo, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpetua Goodall, Morgan Michalowski, Mahmoud Ismail, Monica Christmas, Stephen Schrantz, Ximena Norero, Dora Estripeaut, David Ellis, Kevin Ashi, Samantha Dovgin, Ashtyn Dixon, Xuan Li, Ian Begeman, Sharon Heichman, Joseph Lykins, Delba Villalobos-Cerrud, Lorena Fabrega, Connie Mendivil, Mario R. Quijada, Silvia Fernandez-Pirla, Valli de La Guardia, Digna Wong, Mayrene de LadronGuevara, Carlos Flores, Jovanna Borace, Anabel Garcia, Natividad Caballero, Maria Theresa Moreno de Saez, Michael Politis, Stephanie Ross, Mimansa Dogra, Vishan Dhamsania, Nicholas Graves, Marci Kirchberg, Kopal Mathur, Ashley Aue, Carlos M. Restrepo, Alejandro Llanes, German Guzman, Arturo Rebollon, Kenneth Boyer, Peter Heydemann, A. Gwendolyn Noble, Charles Swisher, Peter Rabiah, Shawn Withers, Teri Hull, Chunlei Su, Michael Blair, Paul Latkany, Ernest Mui, Daniel Vitor Vasconcelos-Santos, Alcibiades Villareal, Ambar Perez, Carlos Andres Naranjo Galvis, Monica Vargas Montes, Nestor Ivan Cardona Perez, Morgan Ramirez, Cy Chittenden, Edward Wang, Laura Lorena Garcia-Lopez, Juliana Munoz-Ortiz, Nicolas Rivera-Valdivia, Maria Cristina Bohorquez-Granados, Gabriela Castano de-la-Torre, Guillermo Padrieu, Juan David Valencia Hernandez, Daniel Celis-Giraldo, John Alejandro Acosta Davila, Elizabeth Torres, Manuela Mejia Oquendo, Jose Y. Arteaga-Rivera, Dan Nicolae, Andrey Rzhetsky, Nancy Roizen, Eileen Stillwaggon, Larry Sawers, Francois Peyron, Martine Wallon, Emanuelle Chapey, Pauline Levigne, Carmen Charter, Migdalia De Frias, Jose Montoya, Cindy Press, Raymund Ramirez, Despina Contopoulos-Ioannidis, Yvonne Maldonado, Oliver Liesenfeld, Carlos Gomez, Kelsey Wheeler, Ellen Holfels, David Frim, David McLone, Richard Penn, William Cohen, Samantha Zehar, James McAuley, Denis Limonne, Sandrine Houze, Sylvie Abraham, Raphael Piarroux, Vera Tesic, Kathleen Beavis, Ana Abeleda, Mari Sautter, Bouchra El Mansouri, Adlaoui El Bachir, Fatima Amarir, Kamal El Bissati, Alejandra de-la-Torre, Gabrielle Britton, Jorge Motta, Eduardo Ortega-Barria, Isabel Luz Romero, Paul Meier, Michael Grigg, Jorge Gomez-Marin, Jagannatha Rao Kosagisharaf, Xavier Saez Llorens, Osvaldo Reyes, Rima McLeod
Summary: This review examines the rates of toxoplasmosis in Panama and Colombia, and explores the relationship between the infection rates and factors such as poverty and proximity to water sources. The study utilizes screening maps, seroprevalence maps, and risk factor mathematical models to identify regions that would benefit from comprehensive, preventive healthcare campaigns.
CURRENT PEDIATRICS REPORTS
(2022)
Article
Immunology
Madiha Sana, Muhammad Rashid, Imran Rashid, Haroon Akbar, Jorge E. Gomez-Marin, Isabelle Dimier-Poisson
Summary: Cytokines play a key role in the immune system and are essential for resisting infections like toxoplasmosis. The balance between pro-inflammatory and anti-inflammatory cytokines is crucial, as excessive production of pro-inflammatory cytokines can lead to tissue damage and enhance the proliferation of Toxoplasma. Immunosuppressed patients are more susceptible to toxoplasmosis. Studying the mechanisms of cytokine secretion and action could provide insights for the treatment and prevention of Toxoplasma infection.
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
(2022)
Article
Health Care Sciences & Services
Manuela Mejia-Oquendo, Elizabeth Marulanda-Ibarra, Jorge Enrique Gomez-Marin
Summary: The world's first evidence-based guidelines for congenital toxoplasmosis was implemented in Colombia in 2013, with positive impacts observed on early diagnosis and treatment of prenatal toxoplasmosis. At the referral centre, all mothers were diagnosed during pregnancy after the implementation of clinical practice guidelines, leading to fewer symptoms with prenatal treatment. In 2018, all mothers at the primary health care centre were diagnosed and treated according to the national guideline.
LANCET REGIONAL HEALTH-AMERICAS
(2021)
Article
Multidisciplinary Sciences
Jorge Enrique Gomez-Marin, Juliana Munoz-Ortiz, Manuela Mejia-Oquendo, Jose Y. Arteaga-Rivera, Nicolas Rivera-Valdivia, Maria Cristina Boh, Stefany Velasco-Velasquez, Gabriela Castano-de-la-Torre, John Alejandro Acosta-Davila, Laura Lorena Garcia-Lopez, Elizabeth Torres-Morales, Monica Vargas, Juan David Valencia, Daniel Celis-Giraldo, Alejandra De-la-Torre
Summary: This study aimed to determine the frequency of retinochoroidal lesions caused by ocular toxoplasmosis and their relationships with risk factors in Armenia-Quindio, Colombia. The results showed that 10.5% of individuals had retinochoroidal scars suggestive of old inactive Toxoplasma gondii infection, and consumption of bottled water was found to be protective against T. gondii infection.
Article
Ophthalmology
Stefany Velasco-Velasquez, Daniel Celis-Giraldo, Andrea Botero Hincapie, Diego Alejandro Hincapie Erira, Sara Sofia Cordero Lopez, Nathalia Marulanda Orozco, Jorge Enrique Gomez-Marin
Summary: This study found that low socioeconomic level was associated with bigger lesions, congenital infection was related with higher frequency of bilateral OT, and intake of boiled water was related to a lower recurrence index of OT.
OPHTHALMIC EPIDEMIOLOGY
(2021)
