Review
Medicine, Research & Experimental
Gabriela Lupusoru, Andreea Gabriella Andronesi, Mircea Lupusoru, Ioana Ailincai, Ruxandra Sfeatcu, Ileana Vacaroiu, Mihaela Banu, Camelia Achim, Gener Ismail
Summary: This study reported two cases of hemorrhagic fever with renal syndrome diagnosed in Romania, where the role of kidney needle biopsy in establishing the diagnosis was emphasized. The rarity of this infection in South-Eastern Europe and the difficulties encountered in diagnosing the disease were also highlighted. Furthermore, the key literature data on the epidemiology, pathogenesis, and management of this infection were reviewed.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2023)
Article
Oncology
Devrim Kahraman, Berkem Karakoyunlu, Ulker Karagece, Umit Ertas, Omer Gunhan
Summary: Desmoplastic fibroma (DF) is a common disease in the jawbones, with nonspecific clinical and radiological features. The immunohistochemical staining results may have limitations in diagnosing DF, suggesting a combined clinical, radiological, and histopathological analysis is essential for diagnosis and management.
JOURNAL OF BONE ONCOLOGY
(2021)
Article
Environmental Sciences
Catherine Allan, Robyn J. Watts
Summary: This paper analyzes interview-derived discourse in order to understand the framing of two trials related to environmental water in the Edward/Kolety-Wakool river system in Australia. The research identifies four different frames of environmental water, each focusing on expert practices and potentially marginalizing other ways of understanding the river system. The study suggests that participants in social learning/adaptive management should be open to exploring alternate framings of situations.
Review
Immunology
Elena Sophia Fratini, Maddalena Migliavacca, Federica Barzaghi, Claudia Fossati, Stefania Giannelli, Ilaria Monti, Miriam Casiraghi, Francesca Ferrua, Salvatore Recupero, Giulia Consiglieri, Valeria Calbi, Francesca Tucci, Vera Gallo, Maria Ester Bernardo, Sabina Cenciarelli, Monica Palmoni, Margherita Moni, Luca Galimberti, Marzia Duse, Lucia Leonardi, Elena Sieni, Elena Soncini, Fulvio Porta, Lucia Dora Notarangelo, Raffaella De Santis, Saverio Ladogana, Alessandro Aiuti, Maria Pia Cicalese
Summary: This article reports two cases of ADA-SCID patients who developed HIS. The first patient developed HIS during enzyme replacement therapy and achieved remission with corticosteroids and immunoglobulin therapy. The second patient developed HIS 2 years after hematopoietic stem cell gene therapy and responded to immunosuppressive therapy. These cases highlight the importance of early identification and varying degrees of immunosuppressive treatment in ADA-SCID patients, with allogeneic HSCT required only in refractory cases.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Construction & Building Technology
B. Ozarisoy, H. Altan
Summary: This paper systematically reviews the existing literature on bio-climatic design systems, exploring how specific passive cooling design strategies can be customized to adapt to local conditions. The study finds that traditional passive cooling design strategies are still effective in current building practices, but some are gradually disappearing due to changes in construction technology.
ENERGY AND BUILDINGS
(2021)
Review
Medicine, General & Internal
Francesco Fabozzi, Silvia Ceccanti, Antonella Cacchione, Giovanna Stefania Colafati, Andrea Carai, Alessandro Crocoli, Angela Mastronuzzi, Denis A. Cozzi
Summary: Primary central nervous system tumors, specifically ependymomas, are the most common solid tumors in childhood, but occurrence outside the CNS is extremely rare. This study presents two cases of extra-CNS myxopapillary ependymomas originating in the sacrococcygeal region, highlighting the challenges in diagnosis, treatment, and follow-up of this rare disease.
Review
Medicine, Research & Experimental
Ying Dai, Tao Sun
Summary: Oguchi's disease is a rare form of congenital stationary night blindness with light-dependent golden fundus discoloration. The characteristic features include metallic sheen on the retina which disappears after dark adaptation, as well as specific changes on electroretinogram confirming the diagnosis. Further research on genes involved in phototransduction and light adaptation is necessary to understand the pathogenesis of this rare disease.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2021)
Review
Oncology
Yongsheng Tang, Xianyu Chen, Xu Lu, Zenan Yuan, Yang Yang, Chunhui Qiu, Hua Li
Summary: This study found that a combination of serological, radiological, and immunohistochemical examinations can aid in the diagnosis of primary hepatic neuroendocrine tumors (PHNETs). Additionally, it was determined that transarterial embolization (TAE) combined with drug therapy could be an effective method for controlling PHNET progression. Regular postoperative follow-ups are important for monitoring the prognosis and tumor progression status of patients with PHNET.
FRONTIERS IN ONCOLOGY
(2023)
Article
Hematology
Yaquine Mechelfekh, Audrey Pontrucher, Jerome Paillassa, Marie Temple, Roch Houot
Summary: Two cases of acute thrombocytopenia after treatment with Obinutuzumab were reported, emphasizing the importance of early detection and treatment of this life-threatening complication.
BRITISH JOURNAL OF HAEMATOLOGY
(2023)
Article
Immunology
Angela Berkhout, Vishal Kapoor, Claire Heney, Cheryl A. Jones, Julia E. Clark, Vikram L. Vaska, Melissa Lai, Clare Nourse
Summary: The incidence of neonatal HSV disease in QLD is almost 3 times the national reported incidence. The study showed that most HSV cases occurred in neonates, presenting with a variety of clinical manifestations. Further research is needed to understand the reasons behind this increase and its implications for medical practice.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Article
Pediatrics
Dan Zhao, Ming Liu, Huafang Jiang, Tianyu Song, Chaolong Xu, Xin Duan, Ruoyu Duan, Han Xu, Zhimei Liu, Fang Fang
Summary: Thiamine pyrophosphokinase (TPK) deficiency is a rare autosomal recessive disorder caused by variants in the TPK1 gene, leading to obstacles in the thiamine metabolic pathway. This study describes two cases of TPK deficiency with different phenotypes and therapeutic effects, and retrospectively reviews 26 previously reported cases to enhance our understanding of the clinical and genetic features of the disease. Patients with TPK deficiency present with various neurological dysfunctions. Different gene variants may result in distinct clinical features and therapeutic effects. Gene analysis is important for the diagnosis of TPK deficiency caused by TPK1 variants, and thiamine supplementation remains the mainstay of treatment for TPK deficiency.
FRONTIERS IN PEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Jiexia Guan, Chang Zhao, Hengming Li, Wenjing Zhang, Weizhen Lin, Luying Tang, Jianning Chen
Summary: Adenomatoid tumors are rare benign neoplasms of mesothelial origin, typically found in the male and female genital tracts. Two new cases were reported in male patients aged 30 and 31, with no distant metastasis observed.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Medicine, General & Internal
Li Li, Guang-Yu Ying, Ya-Juan Tang, Hemmings Wu
Summary: Intradural osteomas located in the subdural or subarachnoid space are rare and lack specificity in clinical manifestations and imaging features. Surgery and pathological examination are essential for diagnosis and craniotomy is a safe and effective treatment.
WORLD JOURNAL OF CLINICAL CASES
(2021)
Review
Chemistry, Multidisciplinary
Aviad Sapir, Daniel M. Kaplan, Benzion Samueli, Rosa Novoa, Ohad Hilly, Sabri El-Saied
Summary: This article summarizes the findings of cases involving mastoid bone in IgG4-related disease (IgG4-RD). Common symptoms include hearing deterioration, tinnitus, and otalgia, with most cases being restricted to otologic manifestations. The diagnosis and treatment of this condition are challenging and require a multidisciplinary team approach.
APPLIED SCIENCES-BASEL
(2022)
Review
Dermatology
Yujing Zhang, Jianzhong Zhang, Cheng Zhou
Summary: Perinevoid alopecia (PA) is a rare type of alopecia areata (AA) that is associated with a pigmented nevus in the center. Two cases of PA were reported in this study, and a review of 14 cases from 11 previous studies was conducted. In one of the cases, PA was found to be combined with a halo nevus, and white terminal hairs were spared in the area of hair loss, which is rarely reported in the literature. It is suggested that antigens from melanocytes may be involved in the development of AA in PA.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2023)
Article
Veterinary Sciences
B. Orr, R. Malik, M. E. Westman, J. M. Norris
Summary: This study found a high seropositivity rate of Coxiella burnetii in pig-hunting dogs above the Tropic of Capricorn in Queensland, with neutered dogs more likely to test positive. A survey of the dogs' owners revealed some had been vaccinated against Q fever and most were aware of potential sources of the pathogen. The findings underscore the importance of awareness among pig hunters about the risk of Q fever exposure and the role their dogs may play in transmitting the disease.
AUSTRALIAN VETERINARY JOURNAL
(2022)
Article
Ecology
Elliot B. Webb, Clare McArthur, Laura Woolfenden, Damien P. Higgins, Mark B. Krockenberger, Valentina S. A. Mella
Summary: Providing wildlife with supplementary water can have positive impacts, but potential negative effects such as predation and disease transmission should be assessed. This study found that koalas, brushtail possums, and foxes visited water stations for longer periods during hot, dry weather, indicating benefits for both native and invasive species. However, the presence of pathogens at the water stations, particularly in summer, poses a potential risk of disease transmission.
Article
Infectious Diseases
Bronwyn Orr, Mark E. Westman, Richard Malik, Auriol Purdie, Scott B. Craig, Jacqueline M. Norris
Summary: The study revealed that approximately one quarter of unvaccinated pig-hunting dogs were seropositive for leptospirosis. The wet tropics region of Far North Queensland was identified as a high-risk area for human exposure to leptospirosis. There was minimal overlap between the serovars dogs were exposed to and those causing disease in humans.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Review
Veterinary Sciences
M. E. Westman, S. J. Coggins, M. van Dorsselaer, J. M. Norris, R. A. Squires, M. Thompson, R. Malik
Summary: Despite the ongoing debate among feline experts about the importance of feline immunodeficiency virus (FIV) on the health and longevity of infected domestic cats, it is recommended that Australian and New Zealand veterinarians take steps to minimize the exposure of cats to FIV. This can be achieved by keeping pet cats indoors or providing secure outdoor access, and testing in-contact cats for FIV. Individual housing of adult cats in animal holding facilities is also advised to limit the spread of FIV infection. Point-of-care (PoC) FIV antibody tests are available, and a dual subtype FIV vaccine offers another avenue for disease prevention. Early detection and treatment of FIV-infected cats is crucial for improving their quality of life and life expectancy.
AUSTRALIAN VETERINARY JOURNAL
(2022)
Article
Environmental Sciences
Patrizia Danesi, Matteo Petini, Christian Falcaro, Michela Bertola, Elisa Mazzotta, Tommaso Furlanello, Mark Krockenberger, Richard Malik
Summary: Pneumocystis, an atypical fungus found in the pulmonary parenchyma of mammals, including humans and dogs, was detected in the bronchoalveolar lavage fluid of 9% of dogs with respiratory distress and/or chronic cough. This suggests that Pneumocystis might play a role as a co-pathogen in some dogs with lower respiratory disease.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Alex Kan, Laura J. Schmertmann, Clare McArthur, Valentina S. A. Mella, Mathew S. Crowther, Luisa Miranda, Richard Malik, Wieland Meyer, Mark B. Krockenberger
Summary: Cryptococcosis caused by Cryptococcus gattii is more prevalent in koalas in Australia, possibly due to their close association with Eucalyptus species. This study investigates the link between nasal colonisation by C. gattii in koalas and the presence of the pathogen in tree hollows.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Behavioral Sciences
Mathew S. Crowther, Adrian Rus, Valentina S. A. Mella, Mark B. Krockenberger, Jasmine Lindsay, Ben D. Moore, Clare McArthur
Summary: This study examines how food quality, shelter availability, and habitat fragmentation influence the tree reuse behavior of koalas. The researchers found that koalas prefer to revisit isolated trees with high leaf nitrogen and spend more time in trees with higher leaf nitrogen and larger size. Tree connectivity reduces travel costs between patches. Food quality and shelter are the main factors driving koalas to revisit specific trees.
BEHAVIORAL ECOLOGY
(2022)
Article
Veterinary Sciences
Eva Spada, Paola Galluzzo, Alessandra Torina, Guido R. Loria, Roberta Perego, Francesca Grippi, Valeria Blanda, Luciana Baggiani, Alessia D'Amico, Maria G. Pennisi, Chris R. Helps, Richard Malik, Mark Westman, Barbara Gandolfi, Sarah Spencer, Daniela Proverbio, Severine Tasker
Summary: This study combines data from two studies and finds an association between the feline AB blood group system and haemoplasma infection. Cats with the Ab genotype have a higher likelihood of haemoplasma infection.
Article
Veterinary Sciences
C. C. Kneipp, A. M. Rose, J. Robson, R. Malik, A. T. Deutscher, A. K. Wiethoelter, S. M. Mor
Summary: This case series describes the presentations, diagnosis, and clinical management of Brucella suis infection in three dogs, including unique features such as the detection of B. suis from milk and isolation from lymph nodes of canine patients. All three dogs showed a favourable clinical response to combination antibiotic therapy with rifampicin and doxycycline.
AUSTRALIAN VETERINARY JOURNAL
(2023)
Article
Veterinary Sciences
M. K. Wun, E. Leister, T. King, R. Korman, R. Malik
Summary: This study describes instances of NSAID-associated acute kidney injury (AKI) in cats and investigates the use of NSAIDs in acute settings among Australian veterinarians. The study recommends against subcutaneous administration of meloxicam in cats, particularly in situations where concurrent complications may occur.
AUSTRALIAN VETERINARY JOURNAL
(2023)
Article
Veterinary Sciences
Laura C. Setyo, Shannon L. Donahoe, Patrick L. Shearer, Penghao Wang, Mark B. Krockenberger
Summary: This study found that tyrosine kinases, including VEGFR2 and PDGFR-beta, are present in canine urothelial carcinomas (UCs). The expression of CDK4 in UC cells is weaker compared to normal and cystitis bladder samples. The overexpression of VEGFR2 suggests that it may serve as a potential therapeutic target in UC.
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION
(2023)
Article
Ecology
Laszlo Irinyi, Michael Roper, Richard Malik, Wieland Meyer
Summary: Yeast species in the Candida haemulonii complex and closely related species are of significant public health concern worldwide. Little is known about their natural habitat. Identifying key environmental habitats is important to understand the emergence of new fungal pathogens.
Article
Virology
Mark E. Westman, Juliana Giselbrecht, Jacqueline M. Norris, Richard Malik, Jennifer Green, Elle Burton-Bradley, Ashley Cheang, Theres Meili, Marina L. Meli, Katrin Hartmann, Regina Hofmann-Lehmann
Summary: This study evaluated the field performance of a new rapid point-of-care test kit in determining different feline leukemia virus (FeLV) infection outcomes, as well as its performance in detecting feline immunodeficiency virus (FIV) infection status. The results showed that the test kit was unable to accurately determine different FeLV infection outcomes in field samples and improvements are needed.
Article
Microbiology
Michaela Henry, Richard Malik, Jan Slapeta, Rogan Lee
Summary: By administering an anthelmintic combination orally to rats, this study effectively prevented the migration of Angiostrongylus cantonensis larvae in the central nervous system, thus preventing pulmonary infections.
Article
Microbiology
Laszlo Irinyi, Richard Malik, Wieland Meyer
Summary: Candida auris is currently the most talked about multidrug-resistant emerging fungal pathogen, posing serious challenges to public health authorities due to its highly contagious nature and difficult-to-control nosocomial outbreaks worldwide. It shows high levels of multidrug-resistance and extreme tolerance to conditions that usually limit fungal transmission. Recently, it has been found in India associated with coastal aquatic environments.
MICROBIOLOGY AUSTRALIA
(2022)