Article
Radiology, Nuclear Medicine & Medical Imaging
Shadi Ebrahimian, Ramandeep Singh, Arjunlokesh Netaji, Kumble Seetharama Madhusudhan, Fatemeh Homayounieh, Andrew Primak, Felix Lades, Sanjay Saini, Mannudeep K. Kalra, Sanjay Sharma
Summary: This study compared the effectiveness of DECT quantitative metrics and radiomics in differentiating pancreatic lesions. Results showed high AUC values for both DECT quantitative metrics and radiomics at two different hospitals.
ACADEMIC RADIOLOGY
(2022)
Article
Oncology
Baptiste Camus, Anna Pellat, Alexandre Rouquette, Ugo Marchese, Anthony Dohan, Arthur Belle, Einas Abou Ali, Stanislas Chaussade, Romain Coriat, Maximilien Barret
Summary: This study assessed the diagnostic yield of a second EUS FNB after an initial negative one. The results showed that the second puncture enabled histological diagnosis in 74% of cases, making it an efficient procedure in this situation. The rate of benign diagnoses after a negative first puncture was 26%, suggesting the importance of a second puncture rather than surgery.
Article
Multidisciplinary Sciences
Kwadwo Antwi, Patricia Wiesner, Elmar M. Merkle, Christoph J. Zech, Daniel T. Boll, Damian Wild, Emanuel Christ, Tobias Heye
Summary: This study analyzed 49 patients with symptoms of endogenous hyperinsulinemic hypoglycemia using MRI and PET/CT imaging, revealing that most PICTs present with atypical signal characteristics and are difficult to detect. A multiparametric approach, including factors like lesion size and different sequence characteristics, is necessary for accurate PICT detection.
Review
Medicine, General & Internal
Claudia Irina Puscasu, Mihai Rimbas, Radu Bogdan Mateescu, Alberto Larghi, Victor Cauni
Summary: Pancreatic cystic lesions are a heterogeneous group of lesions that range from benign to malignant. The prevalence of these lesions has increased in recent years due to advancements in imaging techniques, increased awareness, and an aging population. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is crucial for appropriate treatment and follow-up. Endoscopic ultrasound is a superior diagnostic technique that can identify potentially malignant lesions with high resolution imaging and allows for cyst fluid sampling.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jiayan Huang, Jie Yang, Jianming Ding, Jing Zhou, Rui Yang, Jiawu Li, Yan Luo, Qiang Lu
Summary: The study aims to identify the diagnostic ability of precontrast and contrast-enhanced ultrasound (CEUS) in differentiating between malignant and benign solid pancreatic lesions and develop an easy-to-use diagnostic nomogram. The results show that hypoenhancement in all phases of CEUS, hyperenhancement/isoenhancement followed by washout, an ill-defined border, and a dilated main pancreatic duct are independent risk factors for malignant solid pancreatic lesions. The nomogram constructed based on these predictors has good performance in diagnosing malignant solid pancreatic lesions.
EUROPEAN RADIOLOGY
(2022)
Article
Gastroenterology & Hepatology
Andrea Lisotti, Anna Cominardi, Maria Cristina Conti Bellocchi, Stefano Francesco Crino, Alberto Larghi, Antonio Facciorusso, Paolo Giorgio Arcidiacono, Claudio De Angelis, Francesco Maria Di Matteo, Carlo Fabbri, Helga Bertani, Thomas Togliani, Gianenrico Rizzatti, Mario Brancaccio, Antonino Grillo, Alberto Fantin, Alessandro Pezzoli, Francesca D'Errico, Arnaldo Amato, Filippo Antonini, Amedeo Montale, Antonio Pisani, Edoardo Forti, Mauro Manno, Silvia Carrara, Maria Chiara Petrone, Cecilia Binda, Rocco Maurizio Zagari, Pietro Fusaroli, REUBIO Study Grp
Summary: Repeated EUS-guided tissue acquisition (rEUS-FNB) allows optimal diagnostic performance after nondiagnostic or inconclusive results. Patients' referral to high-volume centers improved diagnostic accuracy, and the use of second-generation FNB needles significantly improved sample adequacy.
DIGESTIVE ENDOSCOPY
(2023)
Article
Oncology
Oscar Paredes, Yoshikuni Kawaguchi, Carlos Luque-Vasquez, Ivan Chavez, Eduardo Payet, Eloy Ruiz, Juan Celis, Francisco Berrospi, Kori Paredes
Summary: Solid pseudopapillary neoplasm (SPN) is frequently diagnosed in young women and has a good overall prognosis after R0 surgical resection, even in cases of recurrence. Age ≥ 28 years, tumor diameter ≥ 10 cm, invasion of adjacent organs, lymph node metastasis (pN +), and AJCC Stage III were identified as predictors for recurrence in resected SPN.
Review
Surgery
Anna Caterina Milanetto, Anna-Lea Gais Zurcher, Lorenzo Macchi, Alina David, Claudio Pasquali
Summary: Pancreatic solid pseudopapillary neoplasm (pSPN) is a rare exocrine tumor that can also occur in male patients. The average age of male patients with pSPN is 34.3 years, with most patients presenting as asymptomatic despite having an average tumor size of 6.3 cm. The majority of surgical treatments are standard pancreatic resections, and the prognosis is generally favorable.
UPDATES IN SURGERY
(2021)
Review
Medicine, General & Internal
Ana Veron Sanchez, Nuria Santamaria Guinea, Silvia Cayon Somacarrera, Ilias Bennouna, Martina Pezzullo, Maria Antonietta Bali
Summary: There are various solid lesions in the pancreas, with pancreatic ductal adenocarcinoma (PDAC) being the most common. However, there are also rare solid pancreatic lesions that have different origins and behaviors. Accurate diagnosis is crucial for optimal patient management.
Review
Medicine, General & Internal
Christopher Kloth, Benedikt Haggenmueller, Annika Beck, Martin Wagner, Marko Kornmann, Jochen P. Steinacker, Nora Steinacker-Stanescu, Daniel Vogele, Meinrad Beer, Markus S. Juchems, Stefan A. Schmidt
Summary: The increasing use of cross-sectional imaging techniques and new technical possibilities has led to a rapid increase in incidentally detected cystic lesions of the pancreas. It is essential to precisely and rapidly classify these lesions for targeted therapeutic considerations. The new European guideline provides recommendations on conservative management and indications for surgery. Radiology plays a crucial role in accurately diagnosing and classifying cystic pancreatic lesions and guiding further treatment.
Review
Medicine, General & Internal
Akashi Fujita, Shomei Ryozawa, Masafumi Mizuide, Yuki Tanisaka, Tomoya Ogawa, Masahiro Suzuki, Hiromune Katsuda, Yoichi Saito, Tomoaki Tashima, Kazuya Miyaguchi, Eiichi Arai, Tomonori Kawasaki, Yumi Mashimo
Summary: Endoscopic ultrasound (EUS) has significant advantages in diagnosing pancreatic solid lesions, subepithelial lesions, and lymph nodes, enabling echostructure assessment in lesions with <1 cm diameter and high resolution imaging. EUS plays an important role in diagnosing these lesions and planning treatment strategies, with future developments expected to further enhance its diagnostic capabilities.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Margaret G. Keane, Elham Afghani
Summary: Pancreatic cystic lesions, including precursors of pancreatic cancer, are increasingly common. Approximately 8% of pancreatic cancers arise from these lesions, emphasizing the importance of careful surveillance and timely surgery for early curative resection. New diagnostic tests and technologies show promise in improving accuracy for managing pancreatic cysts.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
In Rae Cho, Seok-Hoo Jeong, Huapyong Kang, Eui Joo Kim, Yeon Suk Kim, Soyoung Jeon, Jae Hee Cho
Summary: This study aimed to determine the optimal strain ratio (SR) value in endoscopic ultrasound-elastography (EUS-EG) for the differential diagnosis of solid pancreatic lesions (SPLs). Retrospective investigation and comparison of patient demographics, SPL characteristics, and EUS-EG revealed that an increased SR value was significantly associated with pancreatic ductal adenocarcinoma (PDAC). The optimal cut-off value for differential diagnosis was confirmed as 17.14 after propensity score matching. EUS-EG can serve as a supplementary diagnostic method for SPLs.
Article
Surgery
Giovanni Marchegiani, Andrea Caravati, Stefano Andrianello, Tommaso Pollini, Giulia Bernardi, Marco Biancotto, Giuseppe Malleo, Claudio Bassi, Roberto Salvia
Summary: Based on the study of the management of presumed SCNs, we found that SCNs still represent an indication for surgery in the real-life scenario, particularly when the tumor is large and symptomatic. Additionally, younger individuals and patients with body/tail lesions are more likely to receive resection. However, there is an urgent need to establish evidence-based consensus on appropriate indications for surgery to guide clinical practice.
Article
Radiology, Nuclear Medicine & Medical Imaging
Pankaj Gupta, Pratyaksha Rana, Yashi Marodia, Jayanta Samanta, Vishal Sharma, Saroj K. Sinha, Harjeet Singh, Vikas Gupta, Thakur Deen Yadav, Radhika Sreenivasan, Kim Vaiphei, Arvind Rajwanshi, Rakesh Kochhar, Manavjit Sandhu
Summary: Contrast-enhanced ultrasound (CEUS) plays an important role in the evaluation of solid pancreatic head lesions (SPHL) and can be used to differentiate pancreatic ductal adenocarcinoma (PDAC) from non-PDAC lesions.
EUROPEAN RADIOLOGY
(2022)
