Calcitonin gene-related peptide as a regulator of neuronal CaMKII–CREB, microglial p38–NFκB and astroglial ERK–Stat1/3 cascades mediating the development of tolerance to morphine-induced analgesia

Ca2+/Calmodulin-Dependent Protein Kinase II  Is Required for the Initiation and Maintenance of Opioid-Induced Hyperalgesia

(2010) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Cell-type specific activation of p38 and ERK mediates calcitonin gene-related peptide involvement in tolerance to morphine-induced analgesia

(2009) Zhiyong Wang et al.   FASEB JOURNAL

EphB receptor signaling in mouse spinal cord contributes to physical dependence on morphine

(2008) Wen-Tao Liu et al.   FASEB JOURNAL

Mechanisms Mediating the Enhanced Gene Transcription of P2X3Receptor by Calcitonin Gene-related Peptide in Trigeminal Sensory Neurons

(2008) Manuela Simonetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat

(2008) Elisa Dominguez et al.   JOURNAL OF NEUROCHEMISTRY

Morphine suppresses intracellular interferon-α expression in neuronal cells

(2008) Qi Wan et al.   JOURNAL OF NEUROIMMUNOLOGY

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1 , Interleukin-6, and Tumor Necrosis Factor-  in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

(2008) Y. Kawasaki et al.   JOURNAL OF NEUROSCIENCE

Activation of TRPV1 Contributes to Morphine Tolerance: Involvement of the Mitogen-Activated Protein Kinase Signaling Pathway

(2008) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

(2008) Tony W Ho et al.   LANCET