Article
Multidisciplinary Sciences
Marcel Reis Queiroz, Maria Elizangela Ramos Junqueira, Alejandra Andrea Roman Lay, Eliana de Aquino Bonilha, Mariane Furtado Borba, Celia Maria Castex Aly, Roberto Aparecido Moreira, Carmen Simone Grilo Diniz
Summary: This study aims to assess neonatal mortality in term liveborn infants in Sao Paulo, Brazil from 2012 to 2017. The study found that neonatal mortality rate is higher in preterm infants and is influenced by hospital type and obstetric interventions.
Article
Nutrition & Dietetics
Vishwajeet Kumar, Aarti Kumar, Shambhavi Mishra, Peiyi Kan, Sana Ashraf, Shambhavi Singh, Keona J. H. Blanks, Michael Baiocchi, Mika Limcaoco, Amit Kumar Ghosh, Alok Kumar, Raghav Krishna, David K. Stevenson, Lu Tian, Gary L. Darmstadt
Summary: The study in rural Uttar Pradesh, India, demonstrated that sunflower seed oil massage for newborn infants led to better weight gain and reduced rates of illnesses, showing the potential benefits of this practice at the population level.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Medicine, General & Internal
Qingning Wang, Veryan Codd, Zahra Raisi-Estabragh, Crispin Musicha, Vasiliki Bountziouka, Stephen Kaptoge, Elias Allara, Emanuele Di Angelantonio, Adam S. Butterworth, Angela M. Wood, John R. Thompson, Steffen E. Petersen, Nicholas C. Harvey, John N. Danesh, Nilesh J. Samani, Christopher P. Nelson
Summary: The study suggests that shorter leukocyte telomere length is associated with a higher risk of adverse COVID-19 outcomes, independent of major risk factors including age. Further research is needed to determine whether this association reflects causality.
Article
Public, Environmental & Occupational Health
Grace Irimu, Jalemba Aluvaala, Lucas Malla, Sylvia Omoke, Morris Ogero, George Mbevi, Mary Waiyego, Caroline Mwangi, Fred Were, David Gathara, Ambrose Agweyu, Samuel Akech, Mike English
Summary: This study analyzed data of neonatal and pediatric admissions in Kenyan public hospitals, highlighting high mortality rates among neonates and significant variations in mortality across hospitals, indicating preventable causes of death.
Article
Pediatrics
Alka Dev, Michelucia Casseus, Wilhermine Jean Baptiste, Emma LeWinter, Patrice Joseph, Peter Wright
Summary: Haiti has the highest rate of neonatal mortality in the Latin America and Caribbean region. Despite the increasing rate of facility births, maternal and neonatal mortality rates have not significantly improved. Little data is available on the clinical characteristics of complications and morbidities among newborns requiring hospitalization after birth and their impact on neonatal mortality. This study found that with modest investments, the mortality rate in a neonatal unit in Haiti was halved.
Article
Environmental Sciences
Esther lvarez-Silvares, Tania Fernandez-Cruz, Monica Bermudez-Gonzalez, Paula Rubio-Cid, Agostinho Almeida, Edgar Pinto, Teresa Seoane-Pillado, Elena Martinez-Carballo
Summary: Placental development plays a crucial role in the progression of pregnancy, and exposure to environmental toxicants, including metals, can have an impact on placenta and subsequently affect pregnancy outcomes. This study investigates the correlation between placental levels of 14 essential and non-essential elements and neonatal weight. The findings suggest that certain metal concentrations in the placenta may influence fetal growth, with cobalt and strontium associated with higher newborn weight, while lithium, molybdenum, and selenium associated with lower newborn weight.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Multidisciplinary Sciences
Hanna Muhlrad, Evelina Bjorkegren, Philip Haraldson, Nina Bohm-Starke, Helena Kopp Kallner, Sophia Brismar Wendel
Summary: This study assessed the association between interpregnancy interval (IPI) and maternal and neonatal morbidity. The findings suggest that in a high-income country, shorter IPIs than what is recommended by the World Health Organization (at least 24-29 months) are associated with lower maternal morbidity and unaffected neonatal morbidity, while longer IPIs are associated with increased maternal and neonatal morbidity.
SCIENTIFIC REPORTS
(2022)
Article
Nutrition & Dietetics
Elaine K. McCarthy, Deirdre M. Murray, Jonathan O'B Hourihane, Louise C. Kenny, Alan D. Irvine, Mairead E. Kiely
Summary: The study found lasting behavioral consequences of neonatal iron deficiency in high-risk children, but no cognitive effects in generally healthy, low-risk populations.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Obstetrics & Gynecology
Vendela Fuxe, Sophia Brismar Wendel, Nina Bohm-Starke, Hanna Muhlrad
Summary: This study examines the association between delivery mode and severe maternal and neonatal morbidity in singleton term breech births. The results show that compared to prelabor cesarean section, vaginal delivery and intrapartum cesarean section have higher odds for maternal morbidity, while vaginal delivery has higher odds for neonatal morbidity.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2022)
Article
Pediatrics
Elizabeth Heiny, Sarah Wolf, Margaux Collins, Polly Durant Kellner, Roberta Pineda
Summary: The study investigated the relationship between infant medical and sociodemographic factors and enrolment in early therapy services following NICU discharge. Results showed that 82% of families enrolled in early therapy services, with factors such as public insurance, maternal psychiatric diagnosis, and having other children at home influencing the decision to enrol. 18% of families declined therapy services despite reduced barriers to access, indicating a need for targeted interventions to increase enrolment rates among this population.
Article
Obstetrics & Gynecology
Nuran Ustun, Meryem Hocaoglu, Abdulkadir Turgut, Sertac Arslanoglu, Fahri Ovali
Summary: The administration of antenatal corticosteroids (ACS) to women at risk for late preterm delivery significantly reduces the incidence of neonatal respiratory morbidity but increases the risk of neonatal hypoglycemia.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Xue Yu, Chunhua He, Yanping Wang, Leni Kang, Lei Miao, Jian Chen, Qihui Zhao, Xiaona Huang, Jun Zhu, Juan Liang, Qi Li, Meixian Wang, Hanmin Liu
Summary: This study analyzed the epidemic characteristics of neonatal mortality due to preterm birth at 28-36 weeks gestation in different regions of China from 2009 to 2018. The study found that preterm birth was the main cause of neonatal deaths, with a significant downward trend in preterm neonatal mortality rates, and there were regional differences in the proportion of preterm neonatal deaths, as well as in the delivery patterns of preterm neonates among different regions.
Article
Public, Environmental & Occupational Health
Ruoqing Chen, Arvid Sjolander, Stefan Johansson, Donghao Lu, Neda Razaz, Kristina Tedroff, Eduardo Villamor, Sven Cnattingius
Summary: The study revealed an inverse dose-response relationship between gestational age and risk of CP, with neurological-related neonatal diseases being the main mediator of CP risk. As gestational age increases, the proportion of CP risk mediated by neonatal morbidity decreases.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Obstetrics & Gynecology
Moti Gulersen, Cynthia Gyamfi-Bannerman, Michelle Greenman, Erez Lenchner, Burton Rochelson, Eran Bornstein
Summary: The timing of antenatal corticosteroid administration in late preterm birth is associated with neonatal outcomes. Giving birth within <2 days after administration increases the risks of transient tachypnea of the newborn and respiratory distress syndrome, while delivering >7 days later reduces the risk of hypoglycemia.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Nursing
Chinemerem Eleke, Sabinah Obele Ngbala-Okpabi, Daprim Ogaji, Ifeyinwa S. Agu, Esther N. Bempong-Eleke
Summary: The study found that in oil-polluted areas, there is a higher risk of preterm birth, slower newborn growth, and higher morbidity rates at 6 weeks postpartum. Efforts should be made to remediate the environment in polluted regions and prevent oil pollution. Further research should investigate the mechanisms of toxicological effects observed and the protection of vulnerable groups in oil-polluted communities.
JOURNAL OF NURSING RESEARCH
(2021)
Article
Geriatrics & Gerontology
Fred B. Ketchum, Jessica Monsees, Alice J. Kim, Tim Schmachtenberg, Amy Kind, Manish Shah, Wolfgang Hoffmann, Jochen Rene Thyrian, Andrea Gilmore-Bykovskyi
Summary: The objective of this study is to identify barriers and facilitators to the use of formal dementia services among underserved and minority groups in the United States and Germany. Through qualitative interviews with caregivers, it was found that limited knowledge, challenges in interacting with healthcare systems, and the alignment of formal services with cultural or ethnic/racial identity were important factors influencing the utilization of dementia care services.
AGING & MENTAL HEALTH
(2023)
Review
Geriatrics & Gerontology
Clarissa Giebel, Katarzyna M. Lion, Klara Lorenz-Dant, Aida Suarez-Gonzalez, Catherine Talbot, Emily Wharton, Jacqueline Cannon, Hilary Tetlow, Jochen Rene Thyrian
Summary: This systematic review examines the impact of the COVID-19 pandemic on people with dementia living in the community or in residential care. The findings indicate that the pandemic has had negative effects on the cognition, physical functioning, and behavior of people with dementia, as well as limited access to care and poorer mental and social health.
AGING & MENTAL HEALTH
(2023)
Review
Geriatrics & Gerontology
Clarissa Giebel, Catherine V. Talbot, Emily Wharton, Klara Lorenz-Dant, Aida Suarez-Gonzalez, Jacqueline Cannon, Hilary Tetlow, Katarzyna M. Lion, Jochen Rene Thyrian
Summary: This study aimed to comprehensively evaluate the early impacts of the COVID-19 pandemic on unpaid dementia carers worldwide. The findings indicated that the pandemic had negative effects on the caregiving tasks, burden, and well-being of unpaid dementia carers. Policy initiatives should focus on providing better mental health support and formal care services for unpaid carers and their relatives with dementia, and further research is needed to explore the long-term implications of carer needs in light of care home restrictions and care delivery.
AGING & MENTAL HEALTH
(2023)
Article
Geriatrics & Gerontology
Jan Dreyer, Johannes Michael Bergmann, Kerstin Koehler, Iris Hochgraeber, Christiane Pinkert, Martina Roes, Jochen Rene Thyrian, Henrik Wiegelmann, Bernhard Holle
Summary: This study analyzed 320 care arrangements for persons with dementia and identified the underlying structures and types of these arrangements. The results contribute to a better understanding of informal dementia home care and can guide the development of tailored support for persons with dementia and their families.
Article
Medicine, General & Internal
Flora Wendel, Alexander Bauer, Iris Blotenberg, Christian Brettschneider, Maresa Buchholz, David Czock, Juliane Doehring, Catharina Escales, Thomas Frese, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans-Helmut Koenig, Margrit Loebner, Melanie Luppa, Rosemarie Schwenker, Jochen Rene Thyrian, Marina Weissenborn, Birgitt Wiese, Isabel Zollinger, Steffi G. Riedel-Heller, Jochen Gensichen
Summary: This study describes the associations between social network, social participation, and depressive symptoms in older individuals at risk for dementia in Germany. The findings suggest that depressive symptoms are associated with smaller social networks and less social participation. Sufficient non-family contacts and weekly social activities play an important role in maintaining mental health among elderly primary care patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Bernhard Michalowsky, Adel Afi, Bernhard Holle, Jochen Rene Thyrian, Wolfgang Hoffmann
Summary: The study aims to describe the characteristics, financing structures, and challenges of regional dementia care networks and the usage of regional financial network support according to SGB XI. The results show that regional dementia networks are highly diverse in structure, and certain factors significantly affect the number of partners and funding sources. The implementation of the amendment may increase the utilization of regional network funding.
Article
Health Care Sciences & Services
Tim Schmachtenberg, Jessica Monsees, Jochen Rene Thyrian
Summary: This study examines the current state and gaps in dementia-specific care in 17 European countries, identifying differences between countries and suggesting the need for transnational concepts and guidelines to address structural inequalities and establish minimum standards in dementia care.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Neurosciences
Roaa Zayed Atef, Bernhard Michalowsky, Anika Raedke, Moritz Platen, Wiebke Mohr, Franka Muehlichen, Jochen Rene Thyrian, Wolfgang Hoffmann
Summary: Hearing loss is common in people with dementia and can lead to social isolation and depression. This study suggests that the use of hearing aids may be associated with improvements in cognitive function, depression, and health-related quality of life in dementia patients.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Clinical Neurology
Emrah Duezel, Jochen Rene Thyrian
Summary: It is important to combine treatment and preventive measures for Alzheimer's disease to maintain cognitive functions as long as possible. However, there are challenges in developing and researching treatment concepts. The use of mobile everyday-life digital technologies can help address these challenges by coordinating prevention efforts and focusing on cognitive health and safety. Relevant digital technologies include mobile apps for recording cognitive functions, coaching lifestyle changes, reducing treatment risks, and improving health competence. These medical products are at different stages of development.
Article
Clinical Neurology
Jochen Rene Thyrian
Summary: Background: Aging healthily and prevention of diseases are national health targets, and there is compelling evidence on modifiable risk factors suitable for preventive measures. Objective: This article defines terms, presents the roots of prevention in laws, strategies, and guidelines, and outlines the risk factors for dementia and effective preventive measures. Material and methods: The available evidence on risk factors, health behavior, and preventive measures is analyzed, and a multimodal intervention and the impact of motivation on behavior change are discussed.
Article
Public, Environmental & Occupational Health
Felix G. Wittmann, Andrea Zuelke, Alexander Pabst, Melanie Luppa, Jochen Rene Thyrian, Anika Kaestner, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Juliane Doehring, Catharina Escales, Jochen Gensichen, Isabel Zoellinger, Robert Philipp Kosilek, Birgitt Wiese, Anke Oey, Hans-Helmut Koenig, Christian Brettschneider, Thomas Frese, Steffi G. G. Riedel-Heller
Summary: This study analyzed the impact of perceived restriction due to government measures on depressive symptoms in older adults at increased risk for dementia in Germany. The results showed that feeling restricted due to COVID-19 measures was associated with higher levels of depressive symptoms, and this association was mediated by perceived stress.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Maria Isabel Cardona, Jessica Monsees, Tim Schmachtenberg, Anna Gruenewald, Jochen Rene Thyrian
Summary: Despite the health benefits of physical activity for people with dementia, their engagement remains low. Previous research has not used implementation science frameworks to explore the barriers and facilitators of physical activity initiatives in this population. Therefore, a more comprehensive understanding of these mediating factors is needed.
Article
Medicine, General & Internal
Isabel Zoellinger, Alexander Bauer, Iris Blotenberg, Christian Brettschneider, Maresa Buchholz, David Czock, Juliane Doehring, Catharina Escales, Thomas Fankhaenel, Thomas Frese, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans-Helmut Koenig, Melanie Luppa, Anke Oey, Alexander Pabst, Linda Sanftenberg, Jochen Rene Thyrian, Julian Weiss, Flora Wendel, Birgitt Wiese, Steffi G. Riedel-Heller, Jochen Gensichen, Piotr Galecki
Summary: In order to develop effective dementia prevention strategies, it is important to understand the risk factors, associated factors, and early signs of dementia. This study found that depressive symptoms, sleeping problems, and higher education levels are significantly associated with subjective cognitive decline (SCD), which is an early form of dementia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Meeting Abstract
Public, Environmental & Occupational Health
F. Wittmann, D. Czock, T. Frese, J. Gensichen, W. Haefeli, W. Hoffmann, H. Kaduszkiewicz, H-H Koenig, J. R. Thyrian, B. Wiese, M. Luppa, S. G. Riedel-Heller
Meeting Abstract
Public, Environmental & Occupational Health
M. Claus, M. Luppa, D. Czock, T. Frese, J. Gensichen, W. Haefeli, W. Hoffmann, H. Kaduszkiewicz, H-H Koenig, B. Wiese, J. R. Thyrian, S. G. Riedel-Heller
