Article
Peripheral Vascular Disease
Michal Schafer, Lorna P. Browne, Uyen Truong, Petter Bjornstad, Shoshana Tell, Janet Snell-Bergeon, Amy Baumgartner, Kendall S. Hunter, Jane E. B. Reusch, Alex J. Barker, Kristen J. Nadeau, Irene E. Schauer
Summary: In this study, researchers tested whether BCQR could improve vascular health in youth with T1D. The results showed that compared to placebo, BCQR could lower blood pressure and improve aortic stiffness and pressure hemodynamics. Therefore, BCQR may help improve arterial stiffness in youth with T1D and longer-term studies are needed to confirm these findings.
Article
Cardiac & Cardiovascular Systems
Oludamilola Akinmolayemi, Denizhan Ozdemir, Philippe Pibarot, Yanglu Zhao, Jonathon Leipsic, Pamela S. Douglas, Wael A. Jaber, Neil J. Weissman, Philipp Blanke, Rebecca T. Hahn
Summary: This study aimed to assess the expected normal echocardiographic hemodynamics of the balloon-expandable transcatheter heart valve (THV) group based on stroke volume index (SVI) in different flow states. The results showed that flow state affects THV hemodynamics, and baseline and follow-up SVI should be considered when predicting THV hemodynamics before and after valve implantation.
JACC-CARDIOVASCULAR IMAGING
(2023)
Review
Critical Care Medicine
Anousone Daulasim, Antoine Vieillard-Baron, Guillaume Geri
Summary: Recent studies suggest that individualized adaptation of hemodynamic management is crucial for septic shock patients, with focus on fluid management and myocardial evaluation. Statistical approaches and machine learning can aid in developing precision medicine and predicting disease progression. Regular assessment of dynamic changes in hemodynamic phenotypes is necessary for optimal patient care.
CURRENT OPINION IN CRITICAL CARE
(2021)
Review
Medicine, General & Internal
Marius Keller, Harry Magunia, Peter Rosenberger, Michael Koeppen
Summary: Hemodynamic disturbances are common and risky in critically ill patients, and invasive monitoring is often necessary but carries complications. Transthoracic echocardiography (TTE) or transesophageal echocardiography (TEE) can provide similar hemodynamic parameters with lower risks. Training in these techniques can help intensivists assess the hemodynamic profile comprehensively.
Article
Oncology
Chang-Lung Lee, Jessica W. Lee, Andrea R. Daniel, Matt Holbrook, Stephanie Hasapis, Ato O. Wright, Jeremy Brownstein, Lorraine Da Silva Campos, Yan Ma, Lan Mao, Dennis Abraham, Cristian T. Badea, David G. Kirsch
Summary: A mouse model of radiation-induced heart disease simulating RT for breast cancer was developed. Noninvasive imaging modalities found no evidence of decreased myocardial perfusion and cardiac dysfunction, but PV loop analysis revealed subtle changes in cardiac function in ApoE(-/-) mice. PV loop analysis may be useful for future preclinical studies of radiation-induced heart disease.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Multidisciplinary Sciences
Dan Zhu, Weiyu Chen, Yuchen Pan, Tingcui Li, Ming Cui, Baoxia Chen
Summary: The study found that maternal age and parity have an impact on cardiac diastolic function, with older pregnant women having a higher probability of impaired diastolic function. Additionally, impaired diastolic function is significantly correlated with the occurrence rate of pre-eclampsia in mid-gestation.
SCIENTIFIC REPORTS
(2021)
Review
Oncology
Haoxiang Jiang, Lu Qiu, Juan Song, Dandan Xu, Lei Sun, Yinbo Feng, Jun Zhao, Jun Qian, Zhiwei Yu, Jin Peng
Summary: Diffuse leptomeningeal glioneuronal tumors are rare neoplasms with unique pathological characteristics and radiological findings, commonly found in children. There is a correlation between imaging classification and pathological findings, emphasizing the importance of early integration of clinical, pathological, and radiological data for appropriate management and prognosis.
FRONTIERS IN ONCOLOGY
(2022)
Article
Pediatrics
Yingping Deng, Xiang Cao, Luc L. Mertens, Patrick J. McNamara
Summary: This study investigated the attitudes, training, and accreditation regarding targeted neonatal echocardiography (TnEcho) among Chinese neonatologists. The survey revealed that 35.1% of respondents used TnEcho in their neonatal intensive care units (NICUs). Most respondents valued the role of TnEcho in providing timely and longitudinal hemodynamic information. However, the lack of experienced practitioners and accredited training programs were perceived as major barriers to implementation.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Cardiac & Cardiovascular Systems
Christopher M. Janson, Maully J. Shah, Kevin F. Kennedy, V. Ramesh Iyer, Tammy L. Sweeten, Andrew C. Glatz, James M. Steven, Michael L. O'Byrne
Summary: A comparison study of anesthesia strategies for pediatric ablation procedures found that there was no significant difference in the rate of negative EPS in patients with supraventricular tachycardia and ectopic atrial tachycardia, regardless of whether GA or MAC was used. However, in patients with premature ventricular contractions/ventricular tachycardia, a higher rate of negative EPS was observed under GA, leading to a higher rate of nonablation.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2021)
Review
Medicine, General & Internal
Massimiliano Cantinotti, Colin Joseph McMahon, Pietro Marchese, Martin Koestenberger, Marco Scalese, Eliana Franchi, Giuseppe Santoro, Nadia Assanta, Xander Jacquemyn, Shelby Kutty, Raffaele Giordano
Summary: The aim of this review is to assess the strengths and limitations of echocardiographic parameters and scores used to predict favorable outcome in complex congenital heart diseases (CHDs) with a borderline right ventricle. A systematic search was conducted in the National Library of Medicine and 22 studies were analyzed. The studies showed variability in the echocardiographic parameters and cutoff values used, making it difficult to determine the recommended measures. Despite these limitations, certain scores and measurements, such as TV/MV ratios and RV end-diastolic area, were found to be accurate predictors of successful repair in larger studies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Taku Omori, Goki Uno, Shunsuke Shimada, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: This study evaluated the impact of a new TR grading scheme on patient outcomes and hemodynamics, showing that VC >= 14 mm was significantly associated with cardiovascular events and poorer hemodynamic parameters. The new hemodynamic subset classification based on cardiac index and right atrial pressure predicted cardiovascular events in severe TR patients, providing additional prognostic value.
CIRCULATION-CARDIOVASCULAR IMAGING
(2021)
Article
Biotechnology & Applied Microbiology
Melissa Baiocchi, Shirley Barsoum, Seyedvahid Khodaei, Jose M. de la Torre Hernandez, Sydney E. Valentino, Emily C. Dunford, Maureen J. MacDonald, Zahra Keshavarz-Motamed
Summary: Due to high individual differences in anatomy and pathophysiology of patients, planning individualized treatment requires patient-specific diagnosis. A new less invasive intervention is transcatheter aortic valve replacement (TAVR), while a computational mechanics framework C3VI-DE also shows promise.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Emergency Medicine
Hong-pei Li, Kun-peng Liu, Lan Yao
Summary: The combinational use of dexmedetomidine and ketamine (DEX-KET) for pediatric sedation shows better sedation outcomes compared to using DEX or KET alone. It shortens the onset and recovery times of sedation, maintains hemodynamic and respiratory stability, and results in a low incidence of adverse events.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Engineering, Biomedical
Stefano Pidello, Simone Frea, Matteo Attisani, Vittoria Lodo, Andrea Baronetto, Lucia Savi, Marco Cingolani, Andrea Rinaudo, Massimo Boffini, Mauro Rinaldi, Gaetano Maria De Ferrari
Summary: Persistent heart failure symptoms or suboptimal hemodynamics are common in LVAD carriers and associated with adverse outcomes. Our group validated a noninvasive echocardiographic protocol to evaluate hemodynamics in LVAD patients. This study aimed to investigate its utility and prognostic role in clinical practice.
Article
Multidisciplinary Sciences
Sjoerd Bouwmeester, Tim van Loon, Meike Ploeg, Thomas P. Mast, Nienke J. Verzaal, Lars B. van Middendorp, Marc Strik, Frans A. van Nieuwenhoven, Lukas R. Dekker, Frits W. Prinzen, Joost Lumens, Patrick Houthuizen
Summary: This study aimed to investigate the mechanisms underlying the progressive changes in left atrial structure and function following mitral regurgitation through experimental canine models and computer simulations. The results showed that acute mitral regurgitation increased left atrial strain without significant dilation, but over time, left atrial strain gradually decreased with dilation. Histology and computer simulations indicated a correlation with progressive eccentric remodeling and fibrosis of the left atrium.
