Polypharmacological Profiles Underlying the Antitumor Property of Salvia miltiorrhiza Root (Danshen) Interfering with NOX-Dependent Neutrophil Extracellular Traps

Citrullinated histone H3, a biomarker of neutrophil extracellular trap formation, predicts the risk of venous thromboembolism in cancer patients

(2018) L.-M. Mauracher et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Danshen improves survival of patients with colon cancer and dihydroisotanshinone I inhibit the proliferation of colon cancer cells via apoptosis and skp2 signaling pathway

(2017) Yin-Yin Lin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Comparative Analysis of the Major Chemical Constituents in Salvia miltiorrhiza Roots, Stems, Leaves and Flowers during Different Growth Periods by UPLC-TQ-MS/MS and HPLC-ELSD Methods

(2017) Huiting Zeng et al.   MOLECULES

Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

(2017) Robert D Gray et al.   THORAX

Danshen improves survival of patients with advanced lung cancer and targeting the relationship between macrophages and lung cancer cells

(2017) Ching-Yuan Wu et al.   Oncotarget

Gene expression of NOX family members and their clinical significance in hepatocellular carcinoma

(2017) Hyuk Soo Eun et al.   Scientific Reports

Tumor-Induced NETosis as a Risk Factor for Metastasis and Organ Failure

(2016) J. Cedervall et al.   CANCER RESEARCH

Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress

(2016) Samer Tohme et al.   CANCER RESEARCH

Pleiotropic effects of herbs characterized with blood-activating and stasis-resolving functions on angiogenesis

(2016) Li Tao et al.   Chinese Journal of Integrative Medicine

NOX2-dependent regulation of inflammation

(2016) K. L. Singel et al.   CLINICAL SCIENCE

Neutrophil extracellular traps: protagonists of cancer progression?

(2016) L Erpenbeck et al.   ONCOGENE

Roles of Reactive Oxygen Species in Anticancer Therapy withSalvia miltiorrhiza Bunge

(2016) Yu-Chiang Hung et al.   Oxidative Medicine and Cellular Longevity

Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps

(2016) J. Park et al.   Science Translational Medicine

Danshen and the Cardiovascular System: New Advances for an Old Remedy

(2016) Nicola Mascolo et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Neutrophil extracellular traps in health and disease

(2016) P Hasler et al.   SWISS MEDICAL WEEKLY

A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination

(2016) Maximilian F. Konig et al.   Frontiers in Immunology

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

(2015) Huw D Lewis et al.   Nature Chemical Biology

Evidence for traditional Chinese medication to treat cardiovascular disease

(2015) Pan-Pan Hao et al.   Nature Reviews Cardiology

SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

(2015) David Nobuhiro Douda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenolcarboxylic acids from medicinal herbs exert anticancer effects through disruption of COX-2 activity

(2014) Li Tao et al.   PHYTOMEDICINE

A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

(2014) A. L. Robertson et al.   Science Translational Medicine

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones

(2013) Colin Longstaff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

(2013) Jonathan Cools-Lartigue et al.   JOURNAL OF CLINICAL INVESTIGATION

The Anticancer Properties of Salvia Miltiorrhiza Bunge (Danshen): A Systematic Review

(2013) Xiuping Chen et al.   MEDICINAL RESEARCH REVIEWS

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

(2013) K. Martinod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release

(2013) Indira Neeli et al.   Frontiers in Immunology

Comprehension of the Unique Characteristics of Traditional Chinese Medicine

(2012) Stevenson Xutian et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Tanshinone IIA reduces apoptosis induced by hydrogen peroxide in the human endothelium-derived EA.hy926 cells

(2012) Lian-qun Jia et al.   JOURNAL OF ETHNOPHARMACOLOGY

Acute and sub-chronic toxicity studies of Danshen injection in Sprague-Dawley rats

(2012) Meng Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Impact of Various Reactive Oxygen Species on the Formation of Neutrophil Extracellular Traps

(2012) Tina Kirchner et al.   MEDIATORS OF INFLAMMATION

Influences of Chloride and Hypochlorite on Neutrophil Extracellular Trap Formation

(2012) Kathryn Akong-Moore et al.   PLoS One

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

(2012) M. Demers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

(2010) K. D. Metzler et al.   BLOOD

Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice

(2010) Yi Gong et al.   INTERNATIONAL JOURNAL OF CANCER

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease

(2010) Sarah Fox et al.   Journal of Innate Immunity