Nrf2 Deficiency Exaggerates Doxorubicin-Induced Cardiotoxicity and Cardiac Dysfunction

A method to measure cardiac autophagic flux in vivo

(2014) Eri Iwai-Kanai et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Doxorubicin induces protein ubiquitination and inhibits proteasome activity during cardiotoxicity

(2013) Balindiwe J.N. Sishi et al.   TOXICOLOGY

Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection

(2012) Martin Štěrba et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy upregulation promotes survival and attenuates doxorubicin-induced cardiotoxicity

(2012) Balindiwe J.N. Sishi et al.   BIOCHEMICAL PHARMACOLOGY

Prior starvation mitigates acute doxorubicin cardiotoxicity through restoration of autophagy in affected cardiomyocytes

(2012) Tomonori Kawaguchi et al.   CARDIOVASCULAR RESEARCH

Effects of doxorubicin cancer therapy on autophagy and the ubiquitin-proteasome system in long-term cultured adult rat cardiomyocytes

(2012) Polychronis Dimitrakis et al.   CELL AND TISSUE RESEARCH

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Up-regulation of p27kip1 contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy

(2011) Jinqing Li et al.   CARDIOVASCULAR RESEARCH

Overexpression of Nrdp1 in the Heart Exacerbates Doxorubicin-Induced Cardiac Dysfunction in Mice

(2011) Yuan Zhang et al.   PLoS One

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

(2011) K.-i. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy During Cardiac Stress: Joys and Frustrations of Autophagy

(2010) Roberta A. Gottlieb et al.   Annual Review of Physiology

Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes

(2010) Paola Marambio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Genetic and Pharmacologic Hydrogen Sulfide Therapy Attenuates Ischemia-Induced Heart Failure in Mice

(2010) John W. Calvert et al.   CIRCULATION

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy in Hypertensive Heart Disease

(2010) Zhao V. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy, Redox Signaling, and Ventricular Remodeling

(2009) Narasimman Gurusamy et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2 Protects Against Maladaptive Cardiac Responses to Hemodynamic Stress

(2009) Jinqing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP

(2009) Craig W. Younce et al.   BIOCHEMICAL JOURNAL

Targeting the Nrf2 pathway against cardiovascular disease

(2009) Jinqing Li et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Transcription Factor GATA4 Inhibits Doxorubicin-induced Autophagy and Cardiomyocyte Death

(2009) Satoru Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome

(2008) Jinbao Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection

(2008) Hua Yuan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure

(2008) Lihe Lu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA