Amyloid Beta: Multiple Mechanisms of Toxicity and Only Some Protective Effects?

Mitochondrion-Derived Reactive Oxygen Species Lead to Enhanced Amyloid Beta Formation

(2012) Kristina Leuner et al.   ANTIOXIDANTS & REDOX SIGNALING

Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory

(2012) Daniela Puzzo et al.   NEUROBIOLOGY OF AGING

Inhibition of AMPA receptor trafficking at hippocampal synapses by β-amyloid oligomers: the mitochondrial contribution

(2012) Yanfang Rui et al.   Molecular Brain

Curcumin activates Wnt/β-catenin signaling pathway through inhibiting the activity of GSK-3β in APPswe transfected SY5Y cells

(2011) Xiong Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Tau Protein Is Required for Amyloid  -Induced Impairment of Hippocampal Long-Term Potentiation

(2011) O. A. Shipton et al.   JOURNAL OF NEUROSCIENCE

Epidemiology of Alzheimer disease

(2011) Christiane Reitz et al.   Nature Reviews Neurology

Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices

(2011) Gerhard Rammes et al.   NEUROPHARMACOLOGY

Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory

(2010) Daniela Puzzo et al.   ANNALS OF NEUROLOGY

Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

(2010) Elena Alberdi et al.   CELL CALCIUM

The Wnt /β-catenin signaling pathway in the adult neurogenesis

(2010) Lin Zhang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

β-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease

(2010) Li Wan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of Extrasynaptic, But Not Synaptic, NMDA Receptors Modifies Amyloid Precursor Protein Expression Pattern and Increases Amyloid-  Production

(2010) K. Bordji et al.   JOURNAL OF NEUROSCIENCE

Loss of  7 Nicotinic Receptors Enhances  -Amyloid Oligomer Accumulation, Exacerbating Early-Stage Cognitive Decline and Septohippocampal Pathology in a Mouse Model of Alzheimer's Disease

(2010) C. M. Hernandez et al.   JOURNAL OF NEUROSCIENCE

The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects

(2010) Kristel Sleegers et al.   TRENDS IN GENETICS

Non-fibrillar amyloid-β peptide reduces NMDA-induced neurotoxicity, but not AMPA-induced neurotoxicity

(2009) Tetsuhiro Niidome et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aβ-mediated ROS production by Cu ions: Structural insights, mechanisms and relevance to Alzheimer's disease

(2009) Christelle Hureau et al.   BIOCHIMIE

Amyloid-β fibrillogenesis: Structural insight and therapeutic intervention

(2009) Kevin A. DaSilva et al.   EXPERIMENTAL NEUROLOGY

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

 -Amyloid Monomers Are Neuroprotective

(2009) M. L. Giuffrida et al.   JOURNAL OF NEUROSCIENCE

Amyloid beta mediates memory formation

(2009) A. Garcia-Osta et al.   LEARNING & MEMORY

The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events

(2009) Kiran Bhaskar et al.   Molecular Neurodegeneration

Meta-analysis of linkage studies for Alzheimer's disease—A web resource

(2009) Amy W. Butler et al.   NEUROBIOLOGY OF AGING

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

(2009) G. Pigino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic transmission block by presynaptic injection of oligomeric amyloid beta

(2009) H. Moreno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt signaling in Alzheimer's disease: Up or down, that is the question

(2008) Rick A.C.M. Boonen et al.   AGEING RESEARCH REVIEWS

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

Structure-Function Implications in Alzheimers Disease: Effect of Aβ Oligomers at Central Synapses

(2008) Waldo Cerpa et al.   Current Alzheimer Research

Processing of Amyloid Precursor Protein and Amyloid Peptide Neurotoxicity

(2008) Pierrot Nathalie et al.   Current Alzheimer Research

A Closer Look at α-Secretase

(2008) Rolf Postina   Current Alzheimer Research

Metal effects on the membrane interactions of amyloid-β peptides

(2008) John D. Gehman et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

β-amyloid and glutamate receptors

(2008) Laura Gasparini et al.   EXPERIMENTAL NEUROLOGY

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

(2008) Sung-Chun Tang et al.   EXPERIMENTAL NEUROLOGY

Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling

(2008) Margaret H. Magdesian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

(2008) Hyoung-gon Lee et al.   NEUROCHEMISTRY INTERNATIONAL

The amyloid  -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

(2008) C. A. Hansson Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE

Amyloid beta peptides and glutamatergic synaptic dysregulation

(2007) Kodeeswaran Parameshwaran et al.   EXPERIMENTAL NEUROLOGY

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL