Expression of Senescence-Associated microRNAs and Target Genes in Cellular Aging and Modulation by Tocotrienol-Rich Fraction

MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence

(2016) Bernard S. Marasa et al.   Aging-US

miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells

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Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts

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MicroRNAs and their roles in aging

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MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis

(2012) Alberto Izzotti et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

MicroRNAs as a novel cellular senescence regulator

(2011) Feng-Jiao Liu et al.   AGEING RESEARCH REVIEWS

MicroRNAs and the cell cycle

(2011) María José Bueno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan

(2011) John R. Speakman et al.   BIOESSAYS

Control of cell proliferation pathways by microRNAs

(2011) María José Bueno et al.   CELL CYCLE

MiR-34, SIRT1, and p53: The feedback loop

(2011) Munekazu Yamakuchi et al.   CELL CYCLE

Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts

(2011) Suzana Makpol et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

(2011) Na Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

miR-449 inhibits cell proliferation and is down-regulated in gastric cancer

(2011) Tony Bou Kheir et al.   Molecular Cancer

TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support

(2011) T. Vergoulis et al.   NUCLEIC ACIDS RESEARCH

Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study

(2011) Siok-Fong Chin et al.   Nutrition & Metabolism

Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence

(2011) Joseph M. Dhahbi et al.   PLoS One

microRNA and aging: A novel modulator in regulating the aging network

(2010) Li-Hsin Chen et al.   AGEING RESEARCH REVIEWS

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

(2010) Matthias Hackl et al.   AGING CELL

Effect of experimental treatment on GAPDH mRNA expression as a housekeeping gene in human diploid fibroblasts

(2010) Azalina Zainuddin et al.   BMC MOLECULAR BIOLOGY

MicroRNA Regulation of Ionizing Radiation-Induced Premature Senescence

(2010) Yong Wang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

microRNA Expression Patterns Reveal Differential Expression of Target Genes with Age

(2010) Nicole Noren Hooten et al.   PLoS One

p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC

(2009) N R Christoffersen et al.   CELL DEATH AND DIFFERENTIATION

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A

(2009) X. Yang et al.   GENES & DEVELOPMENT

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

(2009) Ashish Lal et al.   MOLECULAR CELL

Dicer is regulated by cellular stresses and interferons

(2009) Jennifer L. Wiesen et al.   MOLECULAR IMMUNOLOGY

p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence

(2009) Kaori Fujita et al.   NATURE CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

(2008) Fang Sun et al.   FEBS LETTERS

A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation

(2008) Zuoren Yu et al.   JOURNAL OF CELL BIOLOGY

MicroRNAs in the miR-106b Family Regulate p21/CDKN1A and Promote Cell Cycle Progression

(2008) I. Ivanovska et al.   MOLECULAR AND CELLULAR BIOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression

(2008) M T Pickering et al.   ONCOGENE

p16INK4a Translation Suppressed by miR-24

(2008) Ashish Lal et al.   PLoS One

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time PCR quantification of precursor and mature microRNA

(2007) Thomas D. Schmittgen et al.   METHODS

Reduction of DNA damage in older healthy adults by Tri E® Tocotrienol supplementation

(2007) Siok-Fong Chin et al.   NUTRITION