NADPH Oxidase as a Therapeutic Target for Oxalate Induced Injury in Kidneys

The NADPH Oxidase Family and its Inhibitors

(2012) Paulina Kleniewska et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Antioxidants in Hypertension and Cardiovascular Disease

(2011) E. L. Schiffrin   MOLECULAR INTERVENTIONS

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

A Novel and Specific NADPH Oxidase-1 (Nox1) Small-Molecule Inhibitor Blocks the Formation of Functional Invadopodia in Human Colon Cancer Cells

(2010) Davide Gianni et al.   ACS Chemical Biology

Mutations in DHDPSL Are Responsible For Primary Hyperoxaluria Type III

(2010) Ruth Belostotsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cellular Maintenance and Repair of the Kidney

(2010) Jian-Kan Guo et al.   Annual Review of Physiology

NOX3 NADPH Oxidase Couples Transient Receptor Potential Vanilloid 1 to Signal Transducer and Activator of Transcription 1-Mediated Inflammation and Hearing Loss

(2010) Debashree Mukherjea et al.   ANTIOXIDANTS & REDOX SIGNALING

NOX2 Complex–Derived ROS as Immune Regulators

(2010) Outi Sareila et al.   ANTIOXIDANTS & REDOX SIGNALING

Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

(2010) S Wind et al.   BRITISH JOURNAL OF PHARMACOLOGY

Signaling by ROS drives inflammasome activation

(2010) Fabio Martinon   EUROPEAN JOURNAL OF IMMUNOLOGY

Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis

(2010) Ramona L. McCaffrey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis

(2010) Benoı̂t Laleu et al.   JOURNAL OF MEDICINAL CHEMISTRY

NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon

(2010) Nicolas Coant et al.   MOLECULAR AND CELLULAR BIOLOGY

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

(2010) Joon-Il Jun et al.   NATURE CELL BIOLOGY

Nitric oxide and oxidative stress in vascular disease

(2010) Ulrich Förstermann   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mechanisms and Function of DUOX in Epithelia of the Lung

(2009) Horst Fischer   ANTIOXIDANTS & REDOX SIGNALING

Targeting and Regulation of Reactive Oxygen Species Generation by Nox Family NADPH Oxidases

(2009) Thomas L. Leto et al.   ANTIOXIDANTS & REDOX SIGNALING

Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells

(2009) Alicia N. Lyle et al.   CIRCULATION RESEARCH

Kidney Stones and the Risk for Chronic Kidney Disease

(2009) A. D. Rule et al.   Clinical Journal of the American Society of Nephrology

Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?

(2009) Kenneth McMartin   CLINICAL TOXICOLOGY

Oxidative stress in renal dysfunction: mechanisms, clinical sequelae and therapeutic options

(2009) M P C Kao et al.   JOURNAL OF HUMAN HYPERTENSION

NADPH Oxidase NOX2 Mediates Rapid Cellular Oxidation following ATP Stimulation of Endotoxin-Primed Macrophages

(2009) S. F. Moore et al.   JOURNAL OF IMMUNOLOGY

The primary hyperoxalurias

(2009) Bernd Hoppe et al.   KIDNEY INTERNATIONAL

Nephrocalcinosis: new insights into mechanisms and consequences

(2009) B. A. Vervaet et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Dual oxidases and hydrogen peroxide in a complex dialogue between host mucosae and bacteria

(2009) Abdelmounaaïm Allaoui et al.   TRENDS IN MOLECULAR MEDICINE

Phenotypic and Functional Analysis of Human SLC26A6 Variants in Patients With Familial Hyperoxaluria and Calcium Oxalate Nephrolithiasis

(2008) Carla G. Monico et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Radical-free biology of oxidative stress

(2008) Dean P. Jones   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities

(2008) Shane R. Thomas et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells

(2008) Srikanth Pendyala et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes

(2008) Katrin Schröder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells

(2008) Desmond B. Jay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production

(2008) S DIKALOV et al.   FREE RADICAL BIOLOGY AND MEDICINE

Apocynin: Molecular Aptitudes

(2008) J. Stefanska et al.   MEDIATORS OF INFLAMMATION

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition

(2008) Stavros Selemidis et al.   PHARMACOLOGY & THERAPEUTICS

Nox enzymes in immune cells

(2008) William M. Nauseef   Seminars in Immunopathology

The Primary Hyperoxalurias

(2008) Amy E. Bobrowski et al.   SEMINARS IN NEPHROLOGY

Oxalate in renal stone disease: the terminal metabolite that just won't go away

(2008) Susan R Marengo et al.   Nature clinical practice. Nephrology