Genomic Structure and Variation of Nuclear Factor (Erythroid-Derived 2)-Like 2

NRF2 Mutation Confers Malignant Potential and Resistance to Chemoradiation Therapy in Advanced Esophageal Squamous Cancer

(2015) Tatsuhiro Shibata et al.   NEOPLASIA

Methylation of the KEAP1 gene promoter region in human colorectal cancer

(2012) Naoyuki Hanada et al.   BMC CANCER

Genetic Polymorphisms and Protein Expression of NRF2 and Sulfiredoxin Predict Survival Outcomes in Breast Cancer

(2012) J. M. Hartikainen et al.   CANCER RESEARCH

PM10-induced Hospital Admissions for Asthma and Chronic Obstructive Pulmonary Disease

(2012) Cristina Canova et al.   EPIDEMIOLOGY

The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops

(2012) Diána Papp et al.   FEBS LETTERS

Somatic mutations of the KEAP1 gene in common solid cancers

(2012) Nam Jin Yoo et al.   HISTOPATHOLOGY

Next-generation sequencing of experimental mouse strains

(2012) Binnaz Yalcin et al.   MAMMALIAN GENOME

Genetic Evidence of an Evolutionarily Conserved Role for Nrf2 in the Protection against Oxidative Stress

(2012) K. Mukaigasa et al.   MOLECULAR AND CELLULAR BIOLOGY

NCBI Epigenomics: What’s new for 2013

(2012) Ian M. Fingerman et al.   NUCLEIC ACIDS RESEARCH

Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers

(2012) T Yamadori et al.   ONCOGENE

Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation

(2011) Tin Oo Khor et al.   BIOCHEMICAL PHARMACOLOGY

Regulation ofKEAP1expression by promoter methylation in malignant gliomas and association with patient’s outcome

(2011) Lucia Anna Muscarella et al.   Epigenetics

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Association of Keap1 and Nrf2 Genetic Mutations and Polymorphisms With Endometrioid Endometrial Adenocarcinoma Survival

(2011) Tze Fang Wong et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Mutation of the Nrf2 gene in non-small cell lung cancer

(2011) Yi Hu et al.   MOLECULAR BIOLOGY REPORTS

Mouse genomic variation and its effect on phenotypes and gene regulation

(2011) Thomas M. Keane et al.   NATURE

Gain of Nrf2 Function in Non-Small-Cell Lung Cancer Cells Confers Radioresistance

(2010) Anju Singh et al.   ANTIOXIDANTS & REDOX SIGNALING

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease

(2010) Malin von Otter et al.   BMC Medical Genetics

Effect of NFE2L2 Genetic Polymorphism on the Association Between Oral Estrogen Therapy and the Risk of Venous Thromboembolism in Postmenopausal Women

(2010) J Bouligand et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Fine Mapping in 94 Inbred Mouse Strains Using a High-Density Haplotype Resource

(2010) A. Kirby et al.   GENETICS

Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma

(2010) Seif O. Shaheen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The NRF2 gene variant, -653G/A, is associated with nephritis in childhood-onset systemic lupus erythematosus

(2010) EJ Córdova et al.   LUPUS

Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract

(2010) Malin von Otter et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

(2010) P. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

NCBI Epigenomics: a new public resource for exploring epigenomic data sets

(2010) I. M. Fingerman et al.   NUCLEIC ACIDS RESEARCH

Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice

(2010) Siwang Yu et al.   PLoS One

Maternal Nrf2 and gluthathione-S-transferase polymorphisms do not modify associations of prenatal tobacco smoke exposure with asthma and lung function in school-aged children

(2010) A. J. Henderson et al.   THORAX

The rise of antioxidant signaling—The evolution and hormetic actions of Nrf2

(2010) Jonathan Maher et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin

(2009) Yoo Ri Kim et al.   JOURNAL OF PATHOLOGY

Genome Project Standards in a New Era of Sequencing

(2009) P. S. G. Chain et al.   SCIENCE

Nrf2 protects against airway disorders

(2009) Hye-Youn Cho et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues

(2008) Rui Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

The susceptibility to vitiligo is associated with NF-E2-related factor2 (Nrf2) gene polymorphisms: a study on Chinese Han population

(2008) Cui-Ping Guan et al.   EXPERIMENTAL DERMATOLOGY

Genetic Alteration of Keap1 Confers Constitutive Nrf2 Activation and Resistance to Chemotherapy in Gallbladder Cancer

(2008) Tatsuhiro Shibata et al.   GASTROENTEROLOGY

Accurate whole human genome sequencing using reversible terminator chemistry

(2008) David R. Bentley et al.   NATURE

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

(2007) W OSBURN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH